alpha-(1-Naphthylmethyl)-2-tetrahydrofuranpropionic acid diethylaminoethyl ester oxalate
- CAS No.
- 3200-06-4
- Chemical Name:
- alpha-(1-Naphthylmethyl)-2-tetrahydrofuranpropionic acid diethylaminoethyl ester oxalate
- Synonyms
- ls121;Iridus;eu-1806;CLARANTIN;Acid oxalate;NAFRONYL OXALATE;naftidrofuryloxalate;Nafronyl acid oxalate;hylester,oxalate(1:1);NAFRONYL OXALATE SALT
- CBNumber:
- CB5426302
- Molecular Formula:
- C26H35NO7
- Molecular Weight:
- 473.56
- MDL Number:
- MFCD00079473
- MOL File:
- 3200-06-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 110-111° |
|---|---|
| Boiling point | 574°C (rough estimate) |
| Density | 1.2205 (rough estimate) |
| refractive index | 1.6000 (estimate) |
| storage temp. | Store at -20°C |
| solubility | Freely soluble in water, freely soluble or soluble in ethanol (96 per cent), slightly or sparingly soluble in acetone. |
| form | Solid |
| color | White to off-white |
| Major Application |
forensics and toxicology pharmaceutical (small molecule) |
| InChIKey | SSAJNPNVUYMUCI-UHFFFAOYSA-N |
| SMILES | OC(=O)C(O)=O.CCN(CC)CCOC(=O)C(CC1CCCO1)Cc2cccc3ccccc23 |
| FDA UNII | 5ADB8D9388 |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302+H312 |
| Precautionary statements | P264-P270-P280-P301+P312-P302+P352+P312-P362+P364 |
| PPE | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes | Xn,Xi |
| Risk Statements | 22 |
| Safety Statements | 36 |
| WGK Germany | 3 |
| RTECS | LU5805000 |
| HS Code | 29321900 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Dermal Acute Tox. 4 Oral |
| Toxicity | LD50 oral in rat: 711mg/kg |
alpha-(1-Naphthylmethyl)-2-tetrahydrofuranpropionic acid diethylaminoethyl ester oxalate price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | N1391 | Nafronyl oxalate salt analytical standard | 3200-06-4 | 5G | $107 | 2026-04-30 | Buy |
| Sigma-Aldrich | BP362 | Naftidrofuryl oxalate British Pharmacopoeia (BP) Reference Standard | 3200-06-4 | 100MG | $242 | 2026-04-30 | Buy |
| ChemScene | CS-4704 | Naftidrofuryl oxalate 99.94% | 3200-06-4 | 100mg | $32 | 2026-06-04 | Buy |
| ApexBio Technology | A4798 | Naftidrofuryl oxalate | 3200-06-4 | 100mg | $55 | 2026-05-06 | Buy |
| aablocks | AA00I5ZL | Naftidrofuryl oxalate 98+% | 3200-06-4 | 1g | $14 | 2026-05-29 | Buy |
alpha-(1-Naphthylmethyl)-2-tetrahydrofuranpropionic acid diethylaminoethyl ester oxalate Chemical Properties, Uses, Production
Chemical Properties
White solid
Originator
Dusodril,Roland,W. Germany,1968
Uses
antineoplastic
Manufacturing Process
30 grams (0.106 mol) of β-(1-naphthyl)-β'-tetrahydrofuryl isobutyric acid are
heated under reflux for 8 1/2 hours in 230 cc of isopropanol with 14 grams
(0.103 mol) of β-chloroethyl-N-diethylamine. After evaporation of the
isopropanol in vacuo, the syrupy residue is treated with a solution of K2CO3.
Extraction with ether is carried out after drying over Na2SO4.
Distillation of the extract yields 28.5 grams of a very viscous yellow liquid with
a BP0.95-1.09millibar = 198° to 202°C. The yield is 70.5% (theoretical quantity =
40.5 grams).1.3 grams (0.0103 mol) of dihydrated oxalic acid are dissolved
while being made tepid in 8 cc of acetone. The cooled solution has added
thereto 4 grams (0.0104 mol) of N-diethylaminoethyl-β-(1-naphthyl)-β'-
tetrahydrofuryl isobutyrate, obtained according to the process described above
and dissolved in 10 cc of acetone. The solution is brought to boiling point for
15 minutes. After cooling to ambient temperature, it is placed in a
refrigerator. Crystallization occurs after 2 hours, the crystals which have
formed are separated by centrifuging, and after washing in hexane and drying
in vacuo 3.5 grams of white crystals are obtained. After being recrystallized
three times, in alcohol and then in a mixture of alcohol and ethyl acetate, the
product is analytically pure and has a MP = 110° to 111°C (heating stage).
brand name
Praxilene (Lipha, S.A., France).
Therapeutic Function
Vasodilator
Biological Activity
Vasodilator
Clinical Use
Vasodilator:
Peripheral and cerebral vascular disease
Metabolism
Metabolised by plasma pseudo-cholinesterases to 3 active metabolites.
alpha-(1-Naphthylmethyl)-2-tetrahydrofuranpropionic acid diethylaminoethyl ester oxalate Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Spectrum Chemical Manufacturing Corp. | 021-021-021-67601398-809-809-809 15221380277 | marketing_china@spectrumchemical.com | China | 9643 | 60 |
| Haoyuan Chemexpress Co., Ltd. | 021-58950125 | info@chemexpress.com | China | 7545 | 61 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4853 | 58 |
| Hubei XinyuanShun Chemical Co., Ltd. | 13971561712, 13995564702, 027-50664929 | hbeixys2001@163.com | China | 3110 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Quality Control Solutions Ltd. | 0755-66853366 13670046396 | orders@qcsrm.com | China | 18188 | 56 |
| Chizhou Kailong Import and Export Trade Co., Ltd. | xg01_gj@163.com | China | 9413 | 50 | |
| Guangzhou QiYun Biotechnology Co., Ltd. | 020-61288194 61288195 | 505721671@qq.com | China | 3853 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
View Latest Price from alpha-(1-Naphthylmethyl)-2-tetrahydrofuranpropionic acid diethylaminoethyl ester oxalate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-20 | alpha-(1-Naphthylmethyl)-2-tetrahydrofuranpropionic acid diethylaminoethyl ester oxalate USP/EP/BP
3200-06-4
|
$1.10 | 1g | 99.9% | 100 Tons min | Dideu Industries Group Limited | |
 |
2026-07-27 | Naftidrofuryl oxalate
3200-06-4
|
$34.00-53.00 | 99.77% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-07-27 | Naftidrofuryl oxalate
3200-06-4
|
$34.00-53.00 | 99.77% | 10g | TargetMol Chemicals Inc. |
-
- alpha-(1-Naphthylmethyl)-2-tetrahydrofuranpropionic acid diethylaminoethyl ester oxalate USP/EP/BP
3200-06-4
- $1.10
- 99.9%
- Dideu Industries Group Limited
-
- Naftidrofuryl oxalate
3200-06-4
- $34.00-53.00
- 99.77%
- TargetMol Chemicals Inc.
-
- Naftidrofuryl oxalate
3200-06-4
- $34.00-53.00
- 99.77%
- TargetMol Chemicals Inc.
3200-06-4 (alpha-(1-Naphthylmethyl)-2-tetrahydrofuranpropionic acid diethylaminoethyl ester oxalate) Related Search:
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