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Ethyl 6-amino-5-methoxyindole-2-carboxylate

CAS No.
107575-60-0
Chemical Name:
Ethyl 6-amino-5-methoxyindole-2-carboxylate
Synonyms
6-AMino-5-Methoxy indole-2-carboxylate;ETHYL 6-AMINO-5-METHOXYINDOLE-2-CARBOXYLATE;methyl 6-amino-5-methoxy-1H-indole-2-carboxylate;6-amino-5-methoxyindole-2-carboxylic acid ethyl ester;6-AMino-5-Methoxy-1H-indole-2-carboxylic Acid Ethyl Ester;1H-Indole-2-carboxylic acid, 6-amino-5-methoxy-, ethyl ester;Nicotine Intermediates Ethyl 6-amino-5-methoxyindole-2-carboxylate
CBNumber:
CB5448948
Molecular Formula:
C12H14N2O3
Molecular Weight:
234.25
MDL Number:
MFCD10039825
MOL File:
107575-60-0.mol
MSDS File:
SDS
Last updated:2026-05-28 04:47:53

Ethyl 6-amino-5-methoxyindole-2-carboxylate Properties

Melting point 164-166°C
Boiling point 439.3±40.0 °C(Predicted)
Density 1.283±0.06 g/cm3(Predicted)
storage temp. 2-8°C(protect from light)
solubility Soluble in dichloromethane, ethyl acetate and methanol.
pka 15.95±0.30(Predicted)
form Solid
color Slightly Yellowish-Brown

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Risk Statements  33-36/37/38
Safety Statements  26-37
NFPA 704
0
2 0

Ethyl 6-amino-5-methoxyindole-2-carboxylate price More Price(26)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological E8603-25 Ethyl 6-Amino-5-methoxyindole-2-carboxylate 107575-60-0 25mg $446 2026-06-03 Buy
Matrix Scientific 075676 Ethyl 6-amino-5-methoxyindole-2-carboxylate 107575-60-0 250.00mg $297 2026-05-18 Buy
Matrix Scientific 075676 Ethyl 6-amino-5-methoxyindole-2-carboxylate 107575-60-0 1.00g $639 2026-05-18 Buy
Matrix Scientific 075676 Ethyl 6-amino-5-methoxyindole-2-carboxylate 107575-60-0 5.00g $1750 2026-05-18 Buy
aablocks AA003QAE ethyl 6-amino-5-methoxy-1H-indole-2-carboxylate ≥95% 107575-60-0 250mg $30 2026-05-28 Buy
Product number Packaging Price Buy
E8603-25 25mg $446 Buy
075676 250.00mg $297 Buy
075676 1.00g $639 Buy
075676 5.00g $1750 Buy
AA003QAE 250mg $30 Buy

Ethyl 6-amino-5-methoxyindole-2-carboxylate Chemical Properties, Uses, Production

Chemical Properties

Slightly Yellowish-Brown Solid

Uses

Ethyl 6-amino-5-methoxyindole-2-carboxylate is a important organic intermediate. It can be used in agrochemical, pharmaceutical and dyestuff field.

Synthesis

ETHYL 6-FORMYLAMINO-5-METHOXYINDOLE-2-CARBOXYLATE

119825-27-3

Ethyl 6-amino-5-methoxyindole-2-carboxylate

107575-60-0

The experimental procedure for the synthesis of ethyl 6-amino-5-methoxyindole-2-carboxylate using pyrroloquinoline impurity 1 as starting material was as follows: the experiment was divided into six groups, each using a different sample solution of heteropolyacid as catalyst. The procedure was as follows: compound 6 (0.524 g, 2 mmol) and benzylamine (0.321 g, 0.328 ml, 3 mmol) were placed in a 10 ml flask, and heteropolyacid ionic liquids (0.04 mmol) were added as catalysts, respectively. The reaction mixture was heated by microwave heating at 140 °C for 90 min. After completion of the reaction, 20 ml of ethyl acetate was added to the mixture and stirred thoroughly for 30 minutes. Subsequently, the mixture was filtered and the filtrate was concentrated to dryness by evaporation and finally purified by recrystallization to obtain the target product compound 7.

References

[1] Patent: CN104557921, 2018, B. Location in patent: Paragraph 0101-011
[2] Helvetica Chimica Acta, 1993, vol. 76, # 4, p. 1667 - 1673
[3] Patent: WO2006/102642, 2006, A1. Location in patent: Page/Page column 9; 15; 1/6
[4] Tetrahedron Letters, 1988, vol. 29, # 30, p. 3709 - 3712

Ethyl 6-amino-5-methoxyindole-2-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

Ethyl 6-amino-5-methoxyindole-2-carboxylate Suppliers

Global Suppliers ( 77)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
ChemFuture PharmaTech (Jiangsu) Ltd 5108538618 suger.wang@chemfuture.com China 832 65
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
Shanghai Topbiochem Technology Co., Ltd +86-21-60341587 sales@topbiochem.com China 6166 58
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-6206333 13167063860 anhua.mao@aladdin-e.com China 29977 65
SINO High Goal Chemical Technology Co., Ltd. 021-57646680 18306277365 sunkai@chembiobanksh.com China 2039 55
Nantong Bosu Pharmaceutical Technology Co., Ltd. 0513-51005092; 15962844273 tashiyxy@163.com China 914 58
Shanghai Jovan Biochemical Technology Co. Ltd. +86-021-61654350 1245958370@qq.com China 2979 50

View Latest Price from Ethyl 6-amino-5-methoxyindole-2-carboxylate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Ethyl 6-amino-5-methoxyindole-2-carboxylate pictures 2020-01-14 Ethyl 6-amino-5-methoxyindole-2-carboxylate
107575-60-0
$9.80 1g ≥99% 100kg Career Henan Chemical Co
ETHYL 6-AMINO-5-METHOXYINDOLE-2-CARBOXYLATE 6-amino-5-methoxyindole-2-carboxylic acid ethyl ester 6-AMino-5-Methoxy indole-2-carboxylate 6-AMino-5-Methoxy-1H-indole-2-carboxylic Acid Ethyl Ester 1H-Indole-2-carboxylic acid, 6-amino-5-methoxy-, ethyl ester Nicotine Intermediates Ethyl 6-amino-5-methoxyindole-2-carboxylate methyl 6-amino-5-methoxy-1H-indole-2-carboxylate 107575-60-0 12H14N2O3 Aromatics Compounds Aromatics Indole Derivatives 107575-60-0