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D-Ephedrine hydrochloride

D-Ephedrine hydrochloride structure

CAS No.: 24221-86-1

Chemical Name:: D-Ephedrine hydrochloride

Synonyms: (1S,2R)-(+)-EPHEDRINE HYDROCHLORIDE;CPDD 0048;d-Ephedrine HCl;(+)-Ephedrine.HCl;ErythromycinBaseUsp23;1S,2R(+)-Ephedrine HCl;D-(+)-EPHEDRINE HYDROCHLORIDE;(+)-Ephedrine (hydrochloride);2-MethylaMino-1-phenylpropan-2-ol;Ephedrine, hydrochloride, (+)- (8CI)

CBNumber:: CB5453027

Molecular Formula:: C10H16ClNO

Molecular Weight:: 201.69

MDL Number:: MFCD00064551

MOL File:: 24221-86-1.mol

MSDS File:: SDS

Last updated:2026-05-28 04:52:17

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D-Ephedrine hydrochloride Properties

Melting point	218-220 °C(lit.)
alpha	34.3 º (c=5, H2O)
Flash point	9℃
storage temp.	Refrigerator
solubility	DMF: 10 mg/ml; DMSO: 3 mg/ml; Ethanol: 10 mg/ml; PBS (pH 7.2): 5 mg/ml
form	A crystalline solid
optical activity	[α]23/D +34.3°, c = 5 in H2O
BRN	6118541
CAS DataBase Reference	24221-86-1(CAS DataBase Reference)
EPA Substance Registry System	Benzenemethanol, .alpha.-[(1R)-1-(methylamino)ethyl]-, hydrochloride, (.alpha.S)- (24221-86-1)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS02,GHS06,GHS08

Signal word

Danger

Hazard statements

H225-H301+H311+H331-H370

Precautionary statements

P210-P280-P301+P310+P330-P302+P352+P312-P304+P340+P311

Hazard Codes

Xn,T,F

Risk Statements

22-39/23/24/25-23/24/25-11

Safety Statements

22-25-45-36/37-16-7

RIDADR

UN1230 - class 3 - PG 2 - Methanol, solution

WGK Germany

RTECS

KB1925000

TSCA

TSCA listed

HS Code

29394100

NFPA 704

	0
2		0

D-Ephedrine hydrochloride price More Price(6)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	E-011	(1S,2R)-(+)-Ephedrine hydrochloride 1.0?mg/mL in methanol (as free base), ampule of 1?mL, certified reference material, Cerilliant?	24221-86-1	1mL	$28.4	2026-04-30	Buy
Sigma-Aldrich	857335	(1S,2R)-(+)-Ephedrine hydrochloride 99%	24221-86-1	25g	$80.2	2026-04-30	Buy
Cayman Chemical	14143	(+)-Ephedrine (hydrochloride) ≥98%	24221-86-1	1mg	$26	2026-04-30	Buy
Cayman Chemical	14143	(+)-Ephedrine (hydrochloride) ≥98%	24221-86-1	5mg	$64	2026-04-30	Buy
TRC	TRC-E575005-10MG	(1S,2R)-(+)-Ephedrine Hydrochloride	24221-86-1	10mg	$96	2026-06-03	Buy

Product number	Packaging	Price	Buy
E-011	1mL	$28.4	Buy
857335	25g	$80.2	Buy
14143	1mg	$26	Buy
14143	5mg	$64	Buy
TRC-E575005-10MG	10mg	$96	Buy

D-Ephedrine hydrochloride Chemical Properties, Uses, Production

Chemical Properties

white crystalline powder

Uses

α- and β-Adrenergic agonist. Bronchodilator.

Safety Profile

A poison by intraperitoneal, subcutaneous, and intravenous routes. When heated to decomposition it emits very toxic fumes of HCl and NOx. See also EPHEDRINE

Purification Methods

Recrystallise the hydrochloride from EtOH/Et2O. The free base crystallises from *C6H6 with m 40-41o (Skita et al. Chem Ber 66 974 1933]. [Beilstein 13 H 254, 13 II 375, 13 III 1721, 13 IV 1879.]

D-Ephedrine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

D-Ephedrine hydrochloride Spectrum

D-Ephedrine hydrochloride(24221-86-1)¹HNMR D-Ephedrine hydrochloride(24221-86-1)Raman D-Ephedrine hydrochloride(24221-86-1)IR

24221-86-1 (D-Ephedrine hydrochloride) Related Search:

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chloramphenicol glucuronide (-)-BICUCULLINE METHOCHLORIDE (1S,2R)-(+)-Ephedrine-d3 HCl (N-methyl-d3) - drug precursor (R)-α,α-Bis(3,5-dichlorophenyl)-2-pyrrolidinemethanol hydrochloride (R)-α,α-Bis(3-chlorophenyl)-2-pyrrolidinemethanol hydrochloride

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1of4

2-MethylaMino-1-phenylpropan-2-ol D-(+)-EPHEDRINE HYDROCHLORIDE d-alpha-(1-methylaminoethyl)benzyl alcohol D-ALPHA-(1-METHYLAMINOETHYL)BENZYL ALCOHOL HYDROCHLORIDE alpha-(1-(methylamino)ethyl)-,hydrochloride,(s-(r*,s*))-benzenemethano alpha-[1-(methylamino)ethyl]-,hydrochloride,[s-(theta,s)]-benzenemethano (1S,2R)-(+)-ALPHA-(1-METHYLAMINOETHYL)BENZYL ALCOHOL HYDROCHLORIDE (1S,2R)-2-METHYLAMINO-1-PHENYL-1-PROPANOL HYDROCHLORIDE d-Ephedrine HCl 2-methylamino-1-phenylpropan-2-ol hydrochloride (1S,2R)-(+)-EPHEDRINE HYDROCHLORIDE 99% ErythromycinBaseUsp23 Benzenemethanol, .alpha.-(1R)-1-(methylamino)ethyl-, hydrochloride, (.alpha.S)- (1s,2r)-(+)-α-(1-methylaminoethyl)benzyl alcohol hydrochloride (1S,2R)-(+)-2-(Methylamino)-1-phenylpropan-1-ol hydrochloride Benzenemethanol, α-[(1R)-1-(methylamino)ethyl]-, hydrochloride, (αS)- Benzenemethanol, α-[1-(methylamino)ethyl]-, hydrochloride, [S-(R*,S*)]- CPDD 0048 Ephedrine, hydrochloride, (+)- (8CI) (1S,2R)-(+)-α-(1-Methylaminoethyl)benzyl alcohol hydrochloride, (1S,2R)-(+)-2-Methylamino-1-phenyl-1-propanol hydrochloride, D-α-(1-Methylaminoethyl)benzyl alcohol hydrochloride (1S,2R)-2-Methylamino-1-phenyl-1-propanol hydrochloride, D-α-(1-Methylaminoethyl)benzyl alcohol hydrochloride 1S,2R(+)-Ephedrine HCl (1S,2R)-2-Methylamino-1-phenylpropan-1-ol Benzenemethanol, alpha-(1-(methylamino)ethyl)-, hydrochloride, (S-(R*,S*))- (1S,2R)-(+)-Ephedrine hydrochloride,99% Methanol(Test 1S,2R(+)-Ephedrine HCl 1.0 mg/mL as free base) α-[1-(MethylaMino)ethyl]benzeneMethanol Hydrochloride (+)-Ephedrine (hydrochloride) (+)-Ephedrine.HCl (+)-Ephedrine.HCl, 1mg/ml in Methanol (as free base) (1S,2R)-(+)-Ephedrine Hydrochloride 1.0 mg/ml in Methanol (as free base) (1S,2R)-(+)-EPHEDRINE HYDROCHLORIDE 24221-86-1 AMINE Ephedrine Derivatives Asymmetric Synthesis Chiral Auxiliaries Amines Aromatics Chiral Reagents Intermediates & Fine Chemicals Pharmaceuticals Pharmaceutical Raw Materials