ChemicalBook >> CAS DataBase List >>Noscapine hydrochloride

Noscapine hydrochloride

Noscapine hydrochloride structure

CAS No.: 912-60-7

Chemical Name:: Noscapine hydrochloride

Synonyms: capvalhydrochloride;NOSCAPINEHCL;opianhydrochloride;noscapiniumchlorid;lyobexhydrochloride;nsc5366hydrochloride;vadebexhydrochloride;NOSCAPINE BASE / HCL;Noscapinhydrochlorid;longatinhydrochloride

CBNumber:: CB4168056

Molecular Formula:: C22H24ClNO7

Molecular Weight:: 449.88

MDL Number:: MFCD00082546

MOL File:: 912-60-7.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-09-12 18:52:28

Request For Quotation

Noscapine hydrochloride Properties

Melting point	221-223 °C(lit.)
storage temp.	2-8°C
solubility	Freely soluble in water and in ethanol (96 per cent). Aqueous solutions are slightly acid; the base may be precipitated when the solutions are allowed to stand.
form	Solid
color	Crystals
Merck	13,6752
Major Application	food and beverages
InChIKey	MFLVZFXCSKVCSH-FSKSRBAZNA-N
SMILES	C12=C(CCN(C)[C@@]1([H])[C@@]1([H])OC(=O)C3C(OC)=C(OC)C=CC1=3)C=C1OCOC1=C2OC.Cl \|&1:6,8,r\|
FDA UNII	TTN62ITH9I
NCI Drug Dictionary	noscapine hydrochloride
EPA Substance Registry System	1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-, hydrochloride, (3S)- (912-60-7)
UNSPSC Code	41116107
NACRES	NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H336

Precautionary statements

P301+P312+P330

target organs

Central nervous system

PPE

dust mask type N95 (US), Eyeshields, Gloves

Hazard Codes

Xn,Xi

Risk Statements

Safety Statements

RIDADR

1544

WGK Germany

RTECS

NP7225000

HS Code

2939.19.5000

HazardClass

6.1(b)

PackingGroup

III

Storage Class

11 - Combustible Solids

Hazard Classifications

Acute Tox. 4 Oral
STOT SE 3

Toxicity

cyt-ham:fbr 60 mg/L ESKHA5 96,55,78

NFPA 704

	0
1		0

Noscapine hydrochloride price More Price(36)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	N9007	Noscapine hydrochloride hydrate analytical standard	912-60-7	5g	$98.7	2026-04-30	Buy
Sigma-Aldrich	N9007	Noscapine hydrochloride hydrate analytical standard	912-60-7	25g	$391	2026-04-30	Buy
TCI Chemical	N0963	Noscapine Hydrochloride Hydrate >98.0%(HPLC)(T)	912-60-7	5g	$92	2026-04-30	Buy
Cayman Chemical	17255	Noscapine (hydrochloride) ≥98%	912-60-7	500mg	$41	2026-04-30	Buy
Cayman Chemical	17255	Noscapine (hydrochloride) ≥98%	912-60-7	1g	$62	2026-04-30	Buy

Product number	Packaging	Price	Buy
N9007	5g	$98.7	Buy
N9007	25g	$391	Buy
N0963	5g	$92	Buy
17255	500mg	$41	Buy
17255	1g	$62	Buy

Noscapine hydrochloride Chemical Properties, Uses, Production

Chemical Properties

White or almost white, crystalline powder or colourless crystals, hygroscopic.

Uses

topical fluoroquinolone antibiotic for acne

Uses

Anti-Tussive

Uses

Noscapine Hydrochloride is a bradykinin B and tubulin inhibitor. Anti-viral.

Biological Activity

Opioid alkaloid with several actions. Binds to tubulin, arresting cells in mitosis and inducing apoptosis. Also is an antagonist at bradykinin receptors (pA 2 = 6.68), inhibits carbachol-stimulated phosphoinositol turnover and enhances forskolin-stimulated increases in cAMP levels in CNS tissues. Clinically used antitussive agent.

Safety Profile

Poison by intravenous route.Moderately toxic by ingestion and subcutaneous routes.Mutation data reported. When heated to decomposition itemits very toxic fumes of HCl and NOx.

in vivo

Noscapine (300mg/kg; oral gavage; daily; for 15 days; athymic female mice) hydrochloride treatment reduces tumor growth in mice^[1].

Animal Model:	Athymic female mice (nu/nu) (8-week-old) injected with rat C6 glioma cells^[1]
Dosage:	300mg/kg
Administration:	Oral gavage; daily; for 15 days
Result:	Revealed a significant reduction of tumor volume.

Noscapine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Noscapine hydrochloride Suppliers

Global Suppliers ( 167)

Supplier	Tel	Email	Country	ProdList	Advantage
Qinghai Pharmaceutical Factory Co., Ltd.	--	xcf@qhzhiyao.com、sqj@qhzhiyao.com	China	9	58
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15813	69
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24512	81
LGM Pharma	1-(800)-881-8210	inquiries@lgmpharma.com	United States	2110	70
Tianjin heowns Biochemical Technology Co., Ltd.	400 638 7771	sales@heowns.com	China	14412	57
Spectrum Chemical Manufacturing Corp.	021-021-021-67601398-809-809-809 15221380277	marketing_china@spectrumchemical.com	China	9643	60
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	9920	65
TOKYO CHEMICAL INDUSTRY CO., LTD.	03-36680489	Sales-JP@TCIchemicals.com	Japan	28364	80
TCI Europe	320-37350700	sales@tcieurope.eu	Europe	23654	75
TCI AMERICA	800-4238616	sales@tciamerica.com	Americas	23636	75

Supplier	Advantage
Qinghai Pharmaceutical Factory Co., Ltd.	58
3B Pharmachem (Wuhan) International Co.,Ltd.	69
TCI (Shanghai) Development Co., Ltd.	81
LGM Pharma	70
Tianjin heowns Biochemical Technology Co., Ltd.	57
Spectrum Chemical Manufacturing Corp.	60
BOC Sciences	65
TOKYO CHEMICAL INDUSTRY CO., LTD.	80
TCI Europe	75
TCI AMERICA	75

View Latest Price from Noscapine hydrochloride manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-08-20	NOSCAPINE HYDROCHLORIDE USP/EP/BP 912-60-7	$1.10	1g	99.9%	100Tons min	Dideu Industries Group Limited
2020-11-16	Noscapine Hydrochloride Hydrate 912-60-7	$200.00	1KG	99%	20 Tons	Longyan Tianhua Biological Technology Co., Ltd
2019-07-12	NOSCAPINE HYDROCHLORIDE 912-60-7	$1.00	1KG	99%	1ton	Career Henan Chemical Co

NOSCAPINE HYDROCHLORIDE USP/EP/BP
912-60-7
$1.10
99.9%
Dideu Industries Group Limited

Noscapine Hydrochloride Hydrate
912-60-7
$200.00
99%
Longyan Tianhua Biological Technology Co., Ltd

NOSCAPINE HYDROCHLORIDE
912-60-7
$1.00
99%
Career Henan Chemical Co

Noscapine hydrochloride Spectrum

NOSCAPINE HYDROCHLORIDE(912-60-7)¹HNMR

912-60-7 (Noscapine hydrochloride) Related Search:

3-[(1S)-1-(Dimethylaminoethyl)]phenol (+)-B-HYDRASTINE HCL Methyl 3-methoxysalicylate (S)-1,2,3,4-tetrahydro-1-[(3-hydroxy-4-methoxyphenyl)methyl]-6-methoxy-2-methylisoquinolin-7-ol dioxifedrine

3-Methoxysalicylic acid Ethyl 2-hydroxybenzoate (S)-1-(2-Methoxyphenyl)ethylamine 2-(1-Aminoethyl)-4-hydroxybenzyl alcohol hydrochloride (1S,2R)-2-Amino-1,2-diphenylethanol

Bis(tert-butyldioxyisopropyl)benzene tert-Butyl 1-benzhydryl-3-azetidinylcarbamate Triadimenol A 1-Pyrrolidinobutyronitrile Noscapine hydrochloride

5-Hydroxydopamine hydrochloride 7-Methoxy-1,2,3,4-tetrahydro-isoquinoline hydrochloride (S)-7-Methoxy-1-methyl-1,2,3,4-tetrahydro-isoquinolin-6-ol

1of4

NARCOTINE HYDROCHLORIDE ,3-dioxolo(4,5-g)isoquinolin-5-yl)-,hydrochloride,(s-(r*,s*))- 1(3h)isobenzofuranone,6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1 1-alpha-narcotinehydrochloride capvalhydrochloride coscopinhydrochloride coscotabshydrochloride key-tusscapinehydrochloride longatinhydrochloride lyobexhydrochloride methoxyhydrastinehydrochloride narcomprenhydrochloride narcosinehydrochloride nectadonhydrochloride nsc5366hydrochloride opianhydrochloride opianinehydrochloride terbenolhydrochloride tusscapinehydrochloride vadebexhydrochloride NOSCAPINE EP STANDARD NOSCAPINE USP STANDARD NOSCAPINEHCL (3S)-6,7-DIMETHOXY-3-[(5R)-5,6,7,8-TETRAHYDRO-4-METHOXY-6-METHYL-1,3-DIOXOLO[4,5-G]ISOQUINOLIN-5-YL]-1(3H)-ISOBENZOFURANONE HYDROCHLORIDE 1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-(5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl)-, hydrochloride, [S-(R*,S*)]- 1(3H)-Isobenzofuranone, 6,7-dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-, hydrochloride, (3S)- (9CI) l-Narcotine hydrochloride Narcotine, hydrochloride (7CI, 8CI) NOSCAPINE BASE / HCL Noscapine hydrate hydrochloride 6,7-Dimethoxy-3-(4-methoxy-6-methyl-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]isoquinolin-5-yl)-3H-2-benzofuran-1-one hydrochloride (3S)-6,7-Dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]-1(3H)-isobenzofuranonehydrochloride Noscapine hydrochloride hydrate,Narcotine hydrochloride Narcotine HCl((S,R)-Noscapine) Noscapine HCl(Nectodon) NoscapineHydrochlorideMonohydrate> NOSCAPINE HYDROCHLORIDE USP/EP/BP Noscapinhydrochlorid Papaverine hydrochloride impurity A （NACOTINE HYDROCHLORIDE） noscapiniumchlorid Noscapine hydrochloride solution Noscapine.HCl (Narcotine), 1mg/ml in Methanol (as free base) Noscapine.HCl (Narcotine) Noscapine hydrochloride 912-60-7 C22H23NO7ClH C22H23NO7HCl C22H23NO7HClxH2O C23H23NO7HCl Analytical Standards Analytical Chromatography Product Catalog Alphabetic Chiral Building Blocks Asymmetric Synthesis Complex Molecules NJ - NZ Inhibitors