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PF-06860932

PF-06860932 Structure
PF-06860932 structure
CAS No.
2226970-01-8
Chemical Name:
PF-06860932
Synonyms
PF-06860932;CFTR corrector 6;7H-Pyrrolo[2,3-d]pyrimidine-6-carbonitrile, 4-amino-7-[[1-(2-fluorophenyl)-1H-pyrazol-4-yl]methyl]-5-[2-(trifluoromethyl)-5-pyrimidinyl]-;4-amino-7-{[1-(2-fluorophenyl)pyrazol-4-yl]methyl}-5-[2-(trifluoromethyl)pyrimidin-5-yl]pyrrolo[2,3-d]pyrimidine-6-carbonitrile - [AC78157]
CBNumber:
CB54667293
Molecular Formula:
C22H13F4N9
Molecular Weight:
479.39
MDL Number:
MFCD34470807
MOL File:
2226970-01-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-16 07:06:08
Request For Quotation

PF-06860932 Properties

Boiling point 697.4±55.0 °C(Predicted)
Density 1.60±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
pka 3.23±0.30(Predicted)
form Solid
color White to off-white

PF-06860932 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0135420 CFTR corrector 6 98.15% 2226970-01-8 5mg $401 2026-06-04 Buy
ChemScene CS-0135420 CFTR corrector 6 98.15% 2226970-01-8 10mg $650 2026-06-04 Buy
ChemScene CS-0135420 CFTR corrector 6 98.15% 2226970-01-8 25mg $1300 2026-06-04 Buy
ChemScene CS-0135420 CFTR corrector 6 98.15% 2226970-01-8 50mg $2080 2026-06-04 Buy
Synthonix AC78157 4-amino-7-{[1-(2-fluorophenyl)pyrazol-4-yl]methyl}-5-[2-(trifluoromethyl)pyrimidin-5-yl]pyrrolo[2,3-d]pyrimidine-6-carbonitrile 98% 2226970-01-8 5mg $469.92 2026-05-06 Buy
Product number Packaging Price Buy
CS-0135420 5mg $401 Buy
CS-0135420 10mg $650 Buy
CS-0135420 25mg $1300 Buy
CS-0135420 50mg $2080 Buy
AC78157 5mg $469.92 Buy

PF-06860932 Chemical Properties,Uses,Production

Uses

CFTR corrector 6 is a potent potentiator of Cystic Fibrosis Transmembrane conductance Regulator (CFTR). CFTR corrector 6 has the potential for cystic fibrosis (CF) and other CFTR associated disorders research[1].

Biological Activity

CFTR corrector 6 is a potent potentiator of Cystic Fibrosis Transmembrane conductance Regulator (CFTR). CFTR corrector 6 has the potential for cystic fibrosis (CF) and other CFTR associated disorders research[1]. CFTR corrector 6 (Example 27) has EC50s of 1.25 nM and 1.27 nM for primary cystic fibrosis human bronchial epithelial (CF hBE) cells and fischer rat thyroid (FRT) cell lines[1].

References

[1]. Joseph Walter Strohbach, et al. Pyrrolopyrimidines as cftr potentiators. WO2018094137A1

PF-06860932 Preparation Products And Raw materials

Raw materials

Preparation Products

PF-06860932 Suppliers

Global( 12)Suppliers
Supplier Tel Email Country ProdList Advantage
Kaixin Chemical (Hong Kong) Limited 010-88886666-01 13112345678 loyson@qq.com China 589 55
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
NINGBOBENKANGJS PHARMTECHCO., LTD +8615990591583 15990591583 CHINA 2028 58
Ningbo Benkang jishi Pharmaceutical Technology Co., Ltd. 15990591583 China 6129 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd 4000862158 18117107507 vip@med-life.cn China 4999 58
RD International Technology Co., Limited 18024082417 market@ubiochem.com China 9831 58
Guangzhou Ruidi Biotechnology Co., Ltd. 020-82099279 18988941402 sales@ubiochem.com China 10000 58
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58
Supplier Advantage
Kaixin Chemical (Hong Kong) Limited 55
BOC Sciences 58
NINGBOBENKANGJS PHARMTECHCO., LTD 58
Ningbo Benkang jishi Pharmaceutical Technology Co., Ltd. 58
TargetMol Chemicals Inc. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
Shanghai?Medlife?Pharm-Tech?Co.,?Ltd 58
RD International Technology Co., Limited 58
Guangzhou Ruidi Biotechnology Co., Ltd. 58
TargetMol Chemicals Inc. 58

View Lastest Price from PF-06860932 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
CFTR corrector 6 pictures 2026-07-15 CFTR corrector 6
2226970-01-8
 $476.00-1990.00 10g TargetMol Chemicals Inc.

2226970-01-8(PF-06860932)Related Search:

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1of2

PF-06860932 CFTR corrector 6 7H-Pyrrolo[2,3-d]pyrimidine-6-carbonitrile, 4-amino-7-[[1-(2-fluorophenyl)-1H-pyrazol-4-yl]methyl]-5-[2-(trifluoromethyl)-5-pyrimidinyl]- 4-amino-7-{[1-(2-fluorophenyl)pyrazol-4-yl]methyl}-5-[2-(trifluoromethyl)pyrimidin-5-yl]pyrrolo[2,3-d]pyrimidine-6-carbonitrile - [AC78157] 2226970-01-8