(4-Methoxybenzyloxy)acetic acid
- CAS No.
- 88920-24-5
- Chemical Name:
- (4-Methoxybenzyloxy)acetic acid
- Synonyms
- p-methoxybenzyloxy acetic acid;2-((4-Methoxybenzyl)oxy)acetic acid;(4-METHOXYBENZYLOXY)ACETIC ACID;Acetic acid, 2-[(4-methoxyphenyl)methoxy]-
- CBNumber:
- CB5479595
- Molecular Formula:
- C10H12O4
- Molecular Weight:
- 196.2
- MDL Number:
- MFCD01861881
- MOL File:
- 88920-24-5.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 2-((4-Methoxybenzyl)oxy)acetic Acid | TRC-M331513-50MG | 50mg | $65 |
| 2-((4-Methoxybenzyl)oxy)acetic Acid | TRC-M331513-500MG | 500mg | $193 |
| 2-((4-Methoxybenzyl)oxy)acetic Acid | TRC-M331513-100MG | 100mg | $78 |
| 2-((4-Methoxybenzyl)oxy)acetic acid 98% | OR939102 | 1g | $21 |
| 2-((4-Methoxybenzyl)oxy)acetic acid 98% | OR939102 | 5g | $71 |
| Melting point | 50.8-51.8 °C(Solv: ethyl ether (60-29-7); ligroine (8032-32-4)) |
|---|---|
| Boiling point | 367.4±22.0 °C(Predicted) |
| Density | 1.198±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 3.40±0.10(Predicted) |
| color | White to Off-White |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| HS Code | 2918999090 |
(4-Methoxybenzyloxy)acetic acid price More Price(60)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | TRC-M331513-50MG | 2-((4-Methoxybenzyl)oxy)acetic Acid | 88920-24-5 | 50mg | $65 | 2026-06-03 | Buy |
| TRC | TRC-M331513-500MG | 2-((4-Methoxybenzyl)oxy)acetic Acid | 88920-24-5 | 500mg | $193 | 2026-06-03 | Buy |
| TRC | TRC-M331513-100MG | 2-((4-Methoxybenzyl)oxy)acetic Acid | 88920-24-5 | 100mg | $78 | 2026-06-03 | Buy |
| Apolloscientific | OR939102 | 2-((4-Methoxybenzyl)oxy)acetic acid 98% | 88920-24-5 | 1g | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR939102 | 2-((4-Methoxybenzyl)oxy)acetic acid 98% | 88920-24-5 | 5g | $71 | 2026-06-04 | Buy |
(4-Methoxybenzyloxy)acetic acid Chemical Properties,Uses,Production
Synthesis
79-08-3
105-13-5
88920-24-5
4-Methoxybenzyl alcohol (1 eq.) and bromoacetic acid (1.2 eq.) were dissolved in anhydrous tetrahydrofuran at 0 °C. Sodium hydride (60% w/w, mineral oil dispersion, 3 eq.) was added in three batches. The reaction mixture was stirred at 70 °C for 4 hours. After cooling to room temperature, water was added and the resulting mixture was washed with hexane. The aqueous phase was acidified to pH 2 with 1N hydrochloric acid and subsequently extracted with ethyl acetate. The organic layers were combined, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure. Purification by silica gel column chromatography with hexane solution of 50% ethyl acetate as eluent gave (4-methoxybenzyloxy)acetic acid (0.51 g, 71% yield) as a colorless solid.1H NMR (500 MHz, CDCl3) δ 7.29 (m, 2H), 6.90 (m, 2H), 4.59 (s, 2H), 4.10 (s, 2H), 3.81 ( s, 3H).
References
[1] Bioorganic and medicinal chemistry letters, 2001, vol. 11, # 21, p. 2837 - 2841
[2] Synlett, 2012, vol. 23, # 19, p. 2845 - 2849
[3] Tetrahedron Letters, 2002, vol. 43, # 41, p. 7427 - 7429
[4] Patent: WO2014/144100, 2014, A2. Location in patent: Paragraph 00274
[5] Patent: WO2006/109729, 2006, A1. Location in patent: Page/Page column 138-139
(4-Methoxybenzyloxy)acetic acid Preparation Products And Raw materials
Raw materials
Preparation Products
(4-Methoxybenzyloxy)acetic acid Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 9976 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10236 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30224 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
| Sichuan Biosynce Pharmatech Co., Ltd. | +8619950309693 | diane@biosynce.com | China | 4871 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Shandong Liteng Biotechnology Co. , Ltd. | +86-18663721413 +86-15552573001 | rosy@litengpharm.com | China | 3280 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +86-15350571055 | Sibel@chuanghaibio.com | China | 6085 | 58 |
