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tyclopyrazoflor

tyclopyrazoflor Structure
tyclopyrazoflor structure
CAS No.
1477919-27-9
Chemical Name:
tyclopyrazoflor
Synonyms
tyclopyrazoflor;Propanamide, N-[3-chloro-1-(3-pyridinyl)-1H-pyrazol-4-yl]-N-ethyl-3-[(3,3,3-trifluoropropyl)thio]-
CBNumber:
CB54813632
Molecular Formula:
C16H18ClF3N4OS
Molecular Weight:
406.85
MDL Number:
MFCD31746909
MOL File:
1477919-27-9.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-31 15:25:14
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tyclopyrazoflor Properties

Boiling point 517.3±50.0 °C(Predicted)
Density 1.36±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
form Solid
pka 2.55±0.12(Predicted)
color White to off-white
FDA UNII SJ5CFR2SPH
EPA Substance Registry System Propanamide, N-[3-chloro-1-(3-pyridinyl)-1H-pyrazol-4-yl]-N-ethyl-3-[(3,3,3-trifluoropropyl)thio]- (1477919-27-9)

tyclopyrazoflor price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth CJC91927 Tyclopyrazoflor 1477919-27-9 50mg $3186 2026-06-04 Buy
Biosynth CJC91927 Tyclopyrazoflor 1477919-27-9 0.5g $10525.6 2026-06-04 Buy
ChemScene CS-0069895 Tyclopyrazoflor 98.21% 1477919-27-9 5mg $157 2026-06-04 Buy
ChemScene CS-0069895 Tyclopyrazoflor 98.21% 1477919-27-9 10mg $249 2026-06-04 Buy
ChemScene CS-0069895 Tyclopyrazoflor 98.21% 1477919-27-9 25mg $498 2026-06-04 Buy
Product number Packaging Price Buy
CJC91927 50mg $3186 Buy
CJC91927 0.5g $10525.6 Buy
CS-0069895 5mg $157 Buy
CS-0069895 10mg $249 Buy
CS-0069895 25mg $498 Buy

tyclopyrazoflor Chemical Properties,Uses,Production

Uses

Tyclopyrazoflor is an anthranilamide compound with pesticidal activity.

Definition

ChEBI: Tyclopyrazoflor is a member of the class of pyrazoles that is 1H-pyrazole which is substituted at positions 1, 3 and 4 by a pyridin-3-yl group, chloro group and an ethyl{3-[(3,3,3-trifluoropropyl)sulfanyl]propanoyl}nitrilo group, respectively. It is an insecticide from Dow AgroSciences LLC. It has a role as an insecticide. It is an organofluorine compound, a member of pyrazoles, a member of pyridines, a tertiary carboxamide, an organic sulfide and an organochlorine compound.

Production Methods

Tyclopyrazoflor is produced commercially through a process that begins with a [3+2] cyclization of 3-hydrazinopyridine hydrochloride and methyl acrylate to form a pyrazolidinone, followed by chlorination and oxidation to a disubstituted pyrazole. Regioselective nitration, reduction to the aminopyrazole, and acylation with 3-((3,3,3-trifluoropropyl)thio)propanoyl chloride yield a secondary amide intermediate, which is then alkylated to the final product. Key innovations include a thiol-ene reaction for the trifluoropropyl thioester precursor, achieving high regioselectivity using a benzoyl peroxide/N,N-dimethylaniline initiator system at low temperatures in semibatch mode, and an Ullmann coupling of N-(3-chloro-1H-pyrazol-4-yl)acetamide with 3-bromopyridine, catalysed by copper(I) chloride and 1,2-dimethylethylenediamine.

Mechanism of action

Unclear but thought to interfer with an insect's nervous system, specifically its neurotransmission, interacting with the chordotonal TRPV channels

References

[1] WO 2017140563 A1.

Pesticide Type

Insecticide

tyclopyrazoflor Preparation Products And Raw materials

Raw materials

Preparation Products

tyclopyrazoflor Suppliers

Global( 10)Suppliers
Supplier Tel Email Country ProdList Advantage
Madision Biomedical Co., Ltd. 028-87439248 19150327610;15114076748 553691721@qq.com China 64 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Shanghai Youde Chemical Technology Co., Ltd. 021-37910267 15821801668 sales@udchem.com China 1216 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Zibo Biopolar Rongchuang Pharmaceutical Co. Ltd. 0533-6092686 13371592196 ddliu@bio-polar.cn China 2876 58
Afflon Pharmaceutical (Sichuan) Co., Ltd. 17336178085 1684779048@qq.com China 2263 58
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58
TargetMol Chemicals Inc. +1-781-999-5354; support@targetmol.com United States 38999 58
Supplier Advantage
Madision Biomedical Co., Ltd. 58
TargetMol Chemicals Inc. 58
Shanghai Youde Chemical Technology Co., Ltd. 58
TargetMol Chemicals Inc. 58
Zibo Biopolar Rongchuang Pharmaceutical Co. Ltd. 58
Afflon Pharmaceutical (Sichuan) Co., Ltd. 58
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58

Related articles

View Lastest Price from tyclopyrazoflor manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Tyclopyrazoflor pictures 2026-04-21 Tyclopyrazoflor
1477919-27-9
 $524.00-838.00 10g TargetMol Chemicals Inc.
Tyclopyrazoflor pictures 2025-08-22 Tyclopyrazoflor
1477919-27-9
 $1520.00-2500.00 10g TargetMol Chemicals Inc.

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tyclopyrazoflor Propanamide, N-[3-chloro-1-(3-pyridinyl)-1H-pyrazol-4-yl]-N-ethyl-3-[(3,3,3-trifluoropropyl)thio]- 1477919-27-9 C16H18ClF3N4OS