5-Bromo-2-thiopheneglyoxal hydrate
- CAS No.
- 852619-28-4
- Chemical Name:
- 5-Bromo-2-thiopheneglyoxal hydrate
- Synonyms
- (5-Bromothien-2-yl)glyoxal hydrate;5-Bromo-2-thiopheneglyoxal hydrate;(5-Bromothien-2-yl)glyoxalhydrate95%;(5-Bromothien-2-yl)glyoxal hydrate 95%;5-BROMO-2-THIOPHENEGLYOXAL HYDRATE, 95+%;Ethanone, 1-(5-bromo-2-thienyl)-2,2-dihydroxy-;1-(5-bromo-2-thiophenyl)-2,2-dihydroxyethanone;1-(5-BroMothiophen-2-yl)-2,2-dihydroxyethanone;(5-Bromothien-2-yl)(oxo)acetaldehyde hydrate, 1-(5-Bromothien-2-yl)-2,2-dihydroxyethan-1-one
- CBNumber:
- CB5482711
- Molecular Formula:
- C6H5BrO3S
- Molecular Weight:
- 237.07
- MDL Number:
- MFCD05864647
- MOL File:
- 852619-28-4.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Hazard Codes | Xi |
| Hazard Note | Irritant |
| HS Code | 2934999090 |
5-Bromo-2-thiopheneglyoxal hydrate price More Price(23)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Matrix Scientific | 071652 | 5-Bromo-2-thiopheneglyoxal hydrate | 852619-28-4 | 1.00g | $231 | 2026-05-18 | Buy |
| Matrix Scientific | 071652 | 5-Bromo-2-thiopheneglyoxal hydrate | 852619-28-4 | 5.00g | $599 | 2026-05-18 | Buy |
| Matrix Scientific | 071652 | 5-Bromo-2-thiopheneglyoxal hydrate | 852619-28-4 | 10.00g | $857 | 2026-05-18 | Buy |
| Crysdot | CD11045635 | 1-(5-Bromothiophen-2-yl)-2,2-dihydroxyethanone 95+% | 852619-28-4 | 10g | $242 | 2026-05-26 | Buy |
| Chemenu | CM199222 | 1-(5-Bromothiophen-2-yl)-2,2-dihydroxyethanone 95% | 852619-28-4 | 10g | $228 | 2026-05-26 | Buy |
5-Bromo-2-thiopheneglyoxal hydrate Chemical Properties, Uses, Production
Synthesis
5370-25-2
852619-28-4
General procedure for the synthesis of 1-(5-bromo-2-thienyl)-2,2-dihydroxyacetophenone from 2-acetyl-5-bromothiophene: A mixture of selenium dioxide (8.66 g, 78 mmol), water (2.8 mL), and 1,4-dioxane (75 mL) was heated to reflux until all the solids were completely dissolved (about 15 min). Subsequently, 2-acetyl-5-bromothiophene (8 g, 39 mmol) was added to the reaction system in batches. The reaction mixture was continued to be stirred under reflux conditions for 15 h. Then, it was cooled to room temperature, filtered through a diatomaceous earth pad (1.5 in. x 3 in. dia.) and the filter cake was washed well with ether. The filtrate was concentrated under reduced pressure to give a yellow residue. Kugelrohr distillation (150°C/1 Torr) was carried out on this residue, which was collected to give glyoxal as a yellow oil and immediately added to boiling water. By recrystallization from water, filtration and drying at 37°C and 5 Torr, 1-(5-bromo-2-thienyl)-2,2-dihydroxyacetophenone hydrate was finally obtained as white to pink acicular crystals (6.723 g, 73% yield). The structure of the product was determined by 1H NMR (300 MHz, DMSO-d6) δ 5.43 (t, J = 6.1 Hz, 1H), 6.93 (d, J = 6.1 Hz, 2H), 7.37 (d, J = 4.1 Hz, 1H), 7.81 (d, J = 4.1 Hz, 1H) and 13C NMR (300 MHz, DMSO-d6) δ 90.28, 122.32, 132.23, 135.73, 141.15, 189.6 were confirmed.
References
[1] Patent: WO2005/49611, 2005, A1. Location in patent: Page/Page column 14
[2] Patent: WO2005/49612, 2005, A1. Location in patent: Page/Page column 15-16
[3] Journal of Organic Chemistry, 2016, vol. 81, # 15, p. 6402 - 6408
5-Bromo-2-thiopheneglyoxal hydrate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Shanghai Ennopharm Co., Ltd. | +86 (21) 6435-5022 | China | 4263 | 65 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| Aikon International Limited | 025-58851090 13913916777 | sales01@aikonchem.com | China | 15947 | 58 |
| Shanghai Jizhi Biochemical Technology Co. Ltd. | 021-4009004166/18616739031 18616739031 | 3007523370@qq.com | China | 40000 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52593 | 58 |
| Baoji Guokang Healthchem Co., Ltd. | +86-0917-3909592 +86-13892490616 | gksales1@gk-bio.com | China | 9035 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +86-13203830695 | laboratory@coreychem.com | China | 30203 | 58 |
View Latest Price from 5-Bromo-2-thiopheneglyoxal hydrate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-07-13 | 5-BROMO-2-THIOPHENEGLYOXAL HYDRATE
852619-28-4
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2021-07-10 | 5-BROMO-2-THIOPHENEGLYOXAL HYDRATE
852619-28-4
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-
- 5-BROMO-2-THIOPHENEGLYOXAL HYDRATE
852619-28-4
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 5-BROMO-2-THIOPHENEGLYOXAL HYDRATE
852619-28-4
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
