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DADPS Biotin Alykne

CAS No.
2241685-22-1
Chemical Name:
DADPS Biotin Alykne
Synonyms
DADPS Biotin Alykne;Biotin-PEG4-amino-t-Bu-DADPS-C3-alykne;4,7,10,13-Tetraoxa-16-azaheneicosanamide, 21-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-N-[2-methyl-2-[[(4-pentyn-1-yloxy)diphenylsilyl]oxy]propyl]-17-oxo-
CBNumber:
CB54849426
Molecular Formula:
C42H62N4O9SSi
Molecular Weight:
827.11
MDL Number:
MFCD31811445
MOL File:
2241685-22-1.mol
MSDS File:
SDS
Last updated:2025-07-16 09:55:30

DADPS Biotin Alykne Properties

Boiling point 947.0±65.0 °C(Predicted)
Density 1.19±0.1 g/cm3(Predicted)
storage temp. -20°C, protect from light, stored under nitrogen
form Oil
pka 13.90±0.40(Predicted)
color Colorless to off-white

DADPS Biotin Alykne price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0115872 Biotin-PEG4-amino-t-Bu-DADPS-C3-alykne ≥95% 2241685-22-1 5mg $412 2026-06-04 Buy
ChemScene CS-0115872 Biotin-PEG4-amino-t-Bu-DADPS-C3-alykne ≥95% 2241685-22-1 10mg $661 2026-06-04 Buy
ChemScene CS-0115872 Biotin-PEG4-amino-t-Bu-DADPS-C3-alykne ≥95% 2241685-22-1 25mg $1419 2026-06-04 Buy
BroadPharm bp-24301 DADPS Biotin Alkyne 2241685-22-1 5MG $347 2026-05-24 Buy
BroadPharm bp-24301 DADPS Biotin Alkyne 2241685-22-1 25MG $1024 2026-05-24 Buy
Product number Packaging Price Buy
CS-0115872 5mg $412 Buy
CS-0115872 10mg $661 Buy
CS-0115872 25mg $1419 Buy
bp-24301 5MG $347 Buy
bp-24301 25MG $1024 Buy

DADPS Biotin Alykne Chemical Properties, Uses, Production

Description

DADPS (dialkoxydiphenylsilane) Biotin Alkyne probes eliminate a major limitation of the streptavidin-biotin affinity purification. This reagent contains a biotin moiety and an azide reactive moiety. DADPS probe can be used in biomolecular labeling and proteomic studies.

Uses

Biotin-PEG4-amino-t-Bu-DADPS-C3-alykne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Biotin-PEG4-amino-t-Bu-DADPS-C3-alykne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

DADPS Biotin Alykne Preparation Products And Raw materials

Raw materials

Preparation Products

DADPS Biotin Alykne Suppliers

Global Suppliers ( 16)
Supplier Tel Email Country ProdList Advantage
Xi'an Confluore Biological Technology Co., Ltd. +86-156-80926068 +86-15680926068 1924344760@qq.com China 4229 58
Zhengzhou Acme Chemical Co., Ltd. 037163312495 13303845143 1416159398@qq.com China 10151 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Shanghai Haohong Pharmaceutical Co., Ltd. 400-8210725 4008210725 malulu@leyan.com China 54996 58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd 0431-80514535 19917294565 et@chemextension.com China 5061 58
Jilin Chinese Academy of Sciences-yanshen Technology 18143011203 ET-market@chemextension.com China 38904 58
Shandong Dayou Pharmaceutical Research and Development Co., Ltd. hanfangpharma@126.com 15165037910 hanfangpharma@126.com China 25800 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Henan Mengtai Pharmaceutical Technology Co., Ltd 17634413542 1959525201@qq.com China 9011 58
Shaanxi Xingbei Aike Biotechnology Co., Ltd 029-13572876172 13572876172 1299426101@qq.com China 3855 58

View Latest Price from DADPS Biotin Alykne manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
DADPS Biotin Alykne pictures 2025-06-07 DADPS Biotin Alykne
2241685-22-1
5mg >95.00% 5mg Xian confluore Biological Technology Co., Ltd.
DADPS Biotin Alykne Biotin-PEG4-amino-t-Bu-DADPS-C3-alykne 4,7,10,13-Tetraoxa-16-azaheneicosanamide, 21-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-N-[2-methyl-2-[[(4-pentyn-1-yloxy)diphenylsilyl]oxy]propyl]-17-oxo- 2241685-22-1