DADPS Biotin Alykne manufacturers
- DADPS Biotin Alykne
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2025-06-07
- CAS:2241685-22-1
- Min. Order: 5mg
- Purity: >95.00%
- Supply Ability: 5mg
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| | DADPS Biotin Alykne Basic information |
| Product Name: | DADPS Biotin Alykne | | Synonyms: | DADPS Biotin Alykne;Biotin-PEG4-amino-t-Bu-DADPS-C3-alykne;4,7,10,13-Tetraoxa-16-azaheneicosanamide, 21-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-N-[2-methyl-2-[[(4-pentyn-1-yloxy)diphenylsilyl]oxy]propyl]-17-oxo- | | CAS: | 2241685-22-1 | | MF: | C42H62N4O9SSi | | MW: | 827.11 | | EINECS: | | | Product Categories: | | | Mol File: | 2241685-22-1.mol |  |
| | DADPS Biotin Alykne Chemical Properties |
| Boiling point | 947.0±65.0 °C(Predicted) | | density | 1.19±0.1 g/cm3(Predicted) | | storage temp. | -20°C, protect from light, stored under nitrogen | | form | Oil | | pka | 13.90±0.40(Predicted) | | color | Colorless to off-white |
| | DADPS Biotin Alykne Usage And Synthesis |
| Description | DADPS (dialkoxydiphenylsilane) Biotin Alkyne probes eliminate a major limitation of the streptavidin-biotin affinity purification. This reagent contains a biotin moiety and an azide reactive moiety. DADPS probe can be used in biomolecular labeling and proteomic studies. | | Uses | Biotin-PEG4-amino-t-Bu-DADPS-C3-alykne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Biotin-PEG4-amino-t-Bu-DADPS-C3-alykne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | DADPS Biotin Alykne Preparation Products And Raw materials |
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