5-Methoxy-2-methyl-3-indoleacetic acid

5-Methoxy-2-methyl-3-indoleacetic acid Suppliers list

Company Name:	Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel:	4006356688 18621169109
Email:	market03@meryer.com

Company Name:	Shanghai Hanhong Scientific Co.,Ltd.
Tel:	021-54306202 13764082696
Email:	info@hanhongsci.com

5-Methoxy-2-methyl-3-indoleacetic acid manufacturers

5-Methoxy-2-methyl-3-indoleacetic acid Basic information

Product Name:	5-Methoxy-2-methyl-3-indoleacetic acid
Synonyms:	5-METHOXY-2-METHYL INDOLE ACETIC ACID;Indomethacin impurity 1/5-methoxy-2-methyl-1H-Indole-3-acetic acid;Indomethacin EP Impurity B;Indometacin Impurit Ⅰ:5-Methoxy-2-Methyl-3-IndoleaceticAcid;Indomethacin USP RC A;5-METHOXY-2-METHYLINDOLE-3-ACETIC ACID;(5-METHOXY-2-METHYL-1H-INDOL-3-YL)-ACETIC ACID;5-methoxy-2-methylindol-3-ylacetic acid
CAS:	2882-15-7
MF:	C12H13NO3
MW:	219.24
EINECS:	220-734-7
Product Categories:	Heterocycles;Indole Derivatives;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Indoles and derivatives;Indoles;Heterocyclic Building Blocks;Building Blocks;Heterocyclic Compounds
Mol File:	2882-15-7.mol

5-Methoxy-2-methyl-3-indoleacetic acid Chemical Properties

Melting point	161-163 °C (lit.)
Boiling point	360.05°C (rough estimate)
density	1.1825 (rough estimate)
refractive index	1.5270 (estimate)
storage temp.	2-8°C
solubility	methanol: soluble
pka	4.22±0.30(Predicted)
form	Crystalline Powder
color	Off-white to light yellow or light beige
InChI	1S/C12H13NO3/c1-7-9(6-12(14)15)10-5-8(16-2)3-4-11(10)13-7/h3-5,13H,6H2,1-2H3,(H,14,15)
InChIKey	TXWGINUZLBAKDF-UHFFFAOYSA-N
SMILES	COc1ccc2[nH]c(C)c(CC(O)=O)c2c1
CAS DataBase Reference	2882-15-7(CAS DataBase Reference)

Safety Information

MSDS Information

Provider	Language
ACROS	English
SigmaAldrich	English

5-Methoxy-2-methyl-3-indoleacetic acid Usage And Synthesis

Chemical Properties	slightly yellow fine crystalline powder
Uses	A metabolite of Indomethacin.
Uses	Reactant for preparation of antimalarial agents Reactant for preparation of ndomethacin analogs as cyclooxygenase and lipoxygenase inhibitors with antiinflammatory activity Reactant for preparation of [123I]-indomethacin derivatives as COX-2 targeted imaging agents Reactant for preparation of histone deacetylase inhibitors Reactant for preparation of 2,N6,5′-substituted adenosine derivatives as ligands for A2B adenosine receptor Reactant for preparation of prostaglandin D2 receptor antagonist
Uses	5-Methoxy-2-methyl-3-indoleacetic acid was used for quantitative determination of indomethacin and its major impurities in suppository and capsule formulations by HPLC. 5-Methoxy-2-methyl-3-indoleacetic acid was used in a study to develop fast, sensitive and simultaneous determination of metabolites of serotonin using liquid chromatography with mass spectrometric detection.
Definition	ChEBI: N-Deschlorobenzoyl indomethacin is a member of indole-3-acetic acids.
General Description	5-Methoxy-2-methyl-3-indoleacetic acid is hydrolysis product of indomethacin.

5-Methoxy-2-methyl-3-indoleacetic acid Preparation Products And Raw materials

Preparation Products

Tag:5-Methoxy-2-methyl-3-indoleacetic acid(2882-15-7) Related Product Information

1-(4-CHLOROBENZOYL)-5-METHOXY-2-METHYL-3-INDOLEACETIC ACID 2-Methylindole 4-Chloro-N-(4-Methoxyphenyl)benzaMide, 97% 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-, 2-hydroxypropyl ester 4-Chloro-2-(4-chlorobenzoyl)-1-(4-Methoxyphenyl)hydrazide Benzoic Acid 4-Chlorobenzoic acid Benzoic acid, 4-chloro-, 2,3-dihydroxypropyl ester 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-Methoxy-2-Methyl-, ethyl ester IndoMethacin DiaMide methyl 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetate 1H-Indole-3-acetic acid, 1-(4-chlorobenzoyl)-5-methoxy-2-methyl-,2,3-d ihydroxypropyl ester Indometacin EP Impurity G Indometacin EP Impurity D Indometacin Impurity 17 Methanone, (4-chlorophenyl)[2,6-dichloro-4-(hydroxymethyl)phenyl]- Indometacin Impurity 18 1H-Indole-3-aceticacid,1-(3-chlorobenzoyl)-5-methoxy-2-methyl 2-(4-Methoxyphenyl)hydrazinesulfonic acid sodium salt monohydrate