ChemicalBook >> CAS DataBase List >>KI-7

KI-7

CAS No.
1489263-00-4
Chemical Name:
KI-7
Synonyms
KI-7;KI-74;KI-7, 10 mM in DMSO;2-(1-Benzyl-1H-indol-3-yl)-2-oxo-N-phenylacetamide;1H-Indole-3-acetamide, α-oxo-N-phenyl-1-(phenylmethyl)-;potentiate,Runx2,Osterix,KI7,KI 7,Inhibitor,P1 receptor,inhibit,orthosteric,MSC,cAMP,accumulation,KI-7,Adenosine Receptor,allosteric
CBNumber:
CB54919734
Molecular Formula:
C23H18N2O2
Molecular Weight:
354.41
MDL Number:
MFCD34470323
MOL File:
1489263-00-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:21

KI-7 Properties

Density 1.18±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
pka 10.93±0.70(Predicted)
form Solid
color White to off-white

KI-7 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth PJC26300 KI-7 1489263-00-4 50mg $1077 2026-06-04 Buy
Biosynth PJC26300 KI-7 1489263-00-4 100mg $1496 2026-06-04 Buy
ChemScene CS-0120748 KI-7 99.16% 1489263-00-4 5mg $119 2026-06-04 Buy
ChemScene CS-0120748 KI-7 99.16% 1489263-00-4 10mg $203 2026-06-04 Buy
ChemScene CS-0120748 KI-7 99.16% 1489263-00-4 25mg $417 2026-06-04 Buy
Product number Packaging Price Buy
PJC26300 50mg $1077 Buy
PJC26300 100mg $1496 Buy
CS-0120748 5mg $119 Buy
CS-0120748 10mg $203 Buy
CS-0120748 25mg $417 Buy

KI-7 Chemical Properties, Uses, Production

Uses

KI-7 is an A2B adenosine receptor positive allosteric modulator. KI-7 potentiates the cAMP accumulation induced by the non-selective A2B adenosine receptor agonist NECA (EC50=445.8 nM). KI-7 also potentiates the cAMP accumulation induced by the selective A2B adenosine receptor agonist BAY 60-6583 as well as by adenosine with EC50s of 2390 nM and 2550 nM, respectively[1][2].

storage

Store at +4°C

References

[1] Trincavelli ML, et al. Allosteric modulators of human A2B adenosine receptor. Biochim Biophys Acta. 2014;1840(3):1194-1203. DOI:10.1016/j.bbagen.2013.12.021
[2] Trincavelli ML, et al. Osteoblast differentiation and survival: A role for A2B adenosine receptor allosteric modulators. Biochim Biophys Acta. 2014;1843(12):2957-2966. DOI:10.1016/j.bbamcr.2014.09.013

55654-68-7
62-53-3
1489263-00-4
Synthesis of KI-7 from 1H-Indole-3-acetyl chloride, α-oxo-1-(phenylmethyl)- and Aniline

KI-7 Preparation Products And Raw materials

KI-7 Suppliers

Global Suppliers ( 24)
Supplier Tel Email Country ProdList Advantage
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Shanghai Chaolan Chemical Technology Center QQ:65489617 13301690235 Sales@ATKchemical.com China 9729 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 400-920-5774 sales@glpbio.cn China 6705 58
Nanjing Digger Medical Technology Co. Ltd. 025-025-51191215 18013836722 2399235533@qq.com China 4932 58
Jingmo (Xiamen) Biotechnology Co., Ltd 13621943973; 13621943973 sales@jamxmpharmatech.com China 1191 58
Jinan Jiuli Biotechnology Co. , Ltd. 15865264761 486064515@qq.com China 5000 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 psaitong@jm-bio.com China 27626 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 59929 58
Beijing Biocreative Technology Co., Ltd. 15522676233 3007606172@qq.com China 1246 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58

KI-7 Spectrum

KI-7 1H-Indole-3-acetamide, α-oxo-N-phenyl-1-(phenylmethyl)- KI-74 potentiate,Runx2,Osterix,KI7,KI 7,Inhibitor,P1 receptor,inhibit,orthosteric,MSC,cAMP,accumulation,KI-7,Adenosine Receptor,allosteric 2-(1-Benzyl-1H-indol-3-yl)-2-oxo-N-phenylacetamide KI-7, 10 mM in DMSO 1489263-00-4