4-Iodo-2-nitroaniline
- CAS No.
- 20691-72-9
- Chemical Name:
- 4-Iodo-2-nitroaniline
- Synonyms
- 4-Iodo-2-nitroaniline;4-IODO-2-NITROANILINE 97;4-Iodo-2-nitrophenylamine;4-Iodo-2-nitrobenzenamine;4-Iodo-2-nitroaniline 98%;2-Amino-5-iodonitrobenzene;Benzenamine, 4-iodo-2-nitro-;4-
Iodo- 2- nitroaniline;4-Iodo-2-nitroaniline ISO 9001：2015 REACH
- CBNumber:
- CB5498903
- Molecular Formula:
- C6H5IN2O2
- Molecular Weight:
- 264.02
- MDL Number:
- MFCD06808526
- MOL File:
- 20691-72-9.mol
- MSDS File:
- SDS
| Melting point | 120-123 °C (lit.) |
|---|---|
| Boiling point | 352.9±27.0 °C(Predicted) |
| Density | 2.101±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | -1.19±0.10(Predicted) |
| color | Dark Red to Dark Brown |
| Stability | Air Sensitive |
| InChI | InChI=1S/C6H5IN2O2/c7-4-1-2-5(8)6(3-4)9(10)11/h1-3H,8H2 |
| InChIKey | QVCRSYXVWPPBFJ-UHFFFAOYSA-N |
| SMILES | C1(N)=CC=C(I)C=C1[N+]([O-])=O |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H317 | |||||||||
| Precautionary statements | P280-P301+P312+P330-P302+P352 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-43 | |||||||||
| Safety Statements | 36/37 | |||||||||
| WGK Germany | 2 | |||||||||
| HS Code | 2921490090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Skin Sens. 1 |
|||||||||
| NFPA 704 |
|
4-Iodo-2-nitroaniline price More Price(53)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 654108 | 4-Iodo-2-nitroaniline 97% | 20691-72-9 | 10g | $404 | 2023-06-20 | Buy |
| TCI Chemical | I1029 | 4-Iodo-2-nitroaniline >98.0%(GC) | 20691-72-9 | 1g | $29 | 2026-04-30 | Buy |
| TCI Chemical | I1029 | 4-Iodo-2-nitroaniline >98.0%(GC) | 20691-72-9 | 5g | $100 | 2026-04-30 | Buy |
| TRC | TRC-I737143-50MG | 4-Iodo-2-nitroaniline | 20691-72-9 | 50mg | $72 | 2026-06-03 | Buy |
| TRC | TRC-I737143-10MG | 4-Iodo-2-nitroaniline | 20691-72-9 | 10mg | $59 | 2026-06-03 | Buy |
4-Iodo-2-nitroaniline Chemical Properties, Uses, Production
Uses
4-Iodo-2-nitroaniline can be used in organic synthesis.
Synthesis
88-74-4
20691-72-9
The general procedure for the synthesis of 4-iodo-2-nitroaniline from 2-nitroaniline is as follows: iodination in the presence of Na2SO3 (typical procedure). To a 100 mL round bottom flask was added a solution of 3 mmol 2-nitroaniline in 10 mL acetic acid and a solution of KI3 and Na2SO3 prepared in advance by adding 3 mmol iodine and 3 mmol Na2SO3 to the solution. A solution of 3 mmol potassium iodide in 3 mL of water was quickly added. At the same time, a solution of 3 mmol NaIO4 in 5 mL of water was added and 0.5 mL of sulfuric acid was quickly added using a pressure-balanced dropping funnel. The reaction mixture was stirred at 25 °C and the reaction progress was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the mixture was poured into ice-cold water and the solid product, 4-iodo-2-nitroaniline, was isolated by vacuum filtration, washed twice with deionized water and dried under appropriate conditions.
References
[1] Monatshefte fur Chemie, 2002, vol. 133, # 10, p. 1325 - 1330
[2] Tetrahedron Letters, 2006, vol. 47, # 28, p. 4793 - 4796
[3] Russian Journal of Organic Chemistry, 2016, vol. 52, # 3, p. 433 - 436
[4] Zh. Org. Khim., 2016, vol. 52, # 3, p. 433 - 436,4
[5] Tetrahedron, 2003, vol. 59, # 14, p. 2497 - 2518
4-Iodo-2-nitroaniline Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
1of2
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Hongle Biotechnology Co., Ltd | 021-56145923; 4001631568 | sales@honglebiotech.com | China | 1036 | 58 |
| Shanghai Boyle Chemical Co., Ltd. | 021-50182298 021-50180596 | sales@boylechem.com | China | 2202 | 55 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 | |
| Zhangjiagang Specom Biochemical Co., Ltd. | 512-0512-58992291,58992287 18606280718 | admin@spbiochem.com | China | 306 | 62 |
| Beijing Yisiyan Technology Research Center | 010-56645598 13366904824; | bjkaida@163.com | China | 1596 | 59 |
| Shanghai T&W Pharmaceutical Co., Ltd. | +86 21 61551611 | China | 9874 | 58 |
View Latest Price from 4-Iodo-2-nitroaniline manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-14 | 2-Iodo-4-nitroaniline
20691-72-9
|
10g | 99% | 50mt/year | Jinan Finer Chemical Co., Ltd | ||
 |
2019-12-26 | 4-Iodo-2-nitroaniline
20691-72-9
|
$6.60 | 1KG | 97%-99% | 1kg-1000kg | Career Henan Chemical Co |
-
- 2-Iodo-4-nitroaniline
20691-72-9
- $0.00
- 99%
- Jinan Finer Chemical Co., Ltd
-
- 4-Iodo-2-nitroaniline
20691-72-9
- $6.60
- 97%-99%
- Career Henan Chemical Co
