6-Amino-1-methyluracil
- CAS No.
- 2434-53-9
- Chemical Name:
- 6-Amino-1-methyluracil
- Synonyms
- 6-AMINO-1-METHYLPYRIMIDINE-2,4(1H,3H)-DIONE;1-METHYL-6-AMINOURACIL;Linaint-B;Compound 1530-0259;Valine Impurity 16;6-AMINO-1-METHYLURACI;LABOTEST-BB LT00080647;6-AMINO-1-METHYLURACIL;4-AMINO-3-METHYLURACIL;Ligagliptin Impurity 66
- CBNumber:
- CB5666867
- Molecular Formula:
- C5H7N3O2
- Molecular Weight:
- 141.13
- MDL Number:
- MFCD00075366
- MOL File:
- 2434-53-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| 6-Amino-1-methyluracil 97% | 346799 | 25g | $164 |
| 6-Amino-1-methyluracil >98.0%(HPLC)(T) | A2449 | 5g | $72 |
| 6-Amino-1-methyluracil >98.0%(HPLC)(T) | A2449 | 25g | $365 |
| 6-Amino-1-methyluracil ≥98%(HPLC) | 43749 | 5G | $125.39 |
| 6-Amino-1-methyluracil ≥98%(HPLC) | 43749 | 25G | $479.92 |
| More product size | |||
| Melting point | 300 °C |
|---|---|
| Density | 1.339±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Soluble in diluted sodium hydroxide solution. |
| form | powder to crystal |
| pka | 9.26±0.40(Predicted) |
| color | White to Almost white |
| BRN | 127771 |
| InChI | InChI=1S/C5H7N3O2/c1-8-3(6)2-4(9)7-5(8)10/h2H,6H2,1H3,(H,7,9,10) |
| InChIKey | GZLZRPNUDBIQBM-UHFFFAOYSA-N |
| SMILES | C1(=O)N(C)C(N)=CC(=O)N1 |
| CAS DataBase Reference | 2434-53-9(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P270-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| target organs | Respiratory system | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-36/37/38 | |||||||||
| Safety Statements | 26 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29335990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
|||||||||
| NFPA 704 |
|
6-Amino-1-methyluracil price More Price(53)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 346799 | 6-Amino-1-methyluracil 97% | 2434-53-9 | 25g | $164 | 2026-04-30 | Buy |
| TCI Chemical | A2449 | 6-Amino-1-methyluracil >98.0%(HPLC)(T) | 2434-53-9 | 5g | $72 | 2026-04-30 | Buy |
| TCI Chemical | A2449 | 6-Amino-1-methyluracil >98.0%(HPLC)(T) | 2434-53-9 | 25g | $365 | 2021-12-16 | Buy |
| Chem-Impex | 43749 | 6-Amino-1-methyluracil ≥98%(HPLC) | 2434-53-9 | 5G | $125.39 | 2026-05-19 | Buy |
| Chem-Impex | 43749 | 6-Amino-1-methyluracil ≥98%(HPLC) | 2434-53-9 | 25G | $479.92 | 2026-05-19 | Buy |
6-Amino-1-methyluracil Chemical Properties,Uses,Production
Chemical Properties
almost white to slightly beige crystalline powder
Uses
6-Amino-1-methyluracil is known to exert inhibitory effects towards DNA repair glycosylase. It is also known to be used as a flame retardant.
Uses
6-Amino-1-methyluracil may be used in the preparation of 1,1-di methyl-1H-spiro[pyrimido[4,5-b]quinoline-5,5-pyrrolo[2,3-d]pyrimidine]-2,2,4,4,6(1H,3H,3H,7H,1H)-pentaone, via reaction with isatin in the presence of catalytic p-toluene sulfonic acid.
General Description
6-Amino-1-methyluracil is an amino derivative of uracil and its standard molar enthalpy of combustion has been evaluated. Host-guest complexation of 6-amino-1-methyluracil with tetrapropoxycalix[4]arene has been reported.
Synthesis
105-56-6
598-50-5
2434-53-9
GENERAL METHOD: Ethyl cyanoacetate (0.1 mol) was mixed with N-methylurea (0.1 mol) in anhydrous ethanol (290 mL) containing sodium, and the reaction was carried out with reference to literature methods 26-34. The reaction mixture was refluxed for 10-12 hours and subsequently cooled to room temperature. Acidification was carried out by adjusting the pH to 6 with acetic acid. The resulting precipitate was washed with distilled water and dried in a desiccator overnight.
References
[1] Journal of Medicinal Chemistry, 1999, vol. 42, # 13, p. 2344 - 2350
[2] RSC Advances, 2015, vol. 5, # 28, p. 21464 - 21470
[3] Chemical and Pharmaceutical Bulletin, 2013, vol. 61, # 4, p. 477 - 482
[4] Journal of Chemical Research, 2016, vol. 40, # 12, p. 771 - 777
[5] Patent: EP3299371, 2018, A1. Location in patent: Paragraph 0587; 0588
6-Amino-1-methyluracil Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13901 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21588 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29815 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2950 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-173 9270 1263 | 1057@dideu.com | China | 4000 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9636 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 +8613506123987 | marketing1@neostarunited.com | China | 8828 | 58 |
View Lastest Price from 6-Amino-1-methyluracil manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-04 | 6-Amino-1-methyluracil
2434-53-9
|
US $0.00-0.00 / KG | 1KG | 98% | 1ton | Henan Aochuang Chemical Co.,Ltd. | |
 |
2020-05-15 | 6-AMino-1-Methyluracil
2434-53-9
|
US $1.00 / KG | 1KG | 99% | 20T | Shaanxi Dideu Medichem Co. Ltd | |
 |
2019-07-06 | 6-Amino-1-methyluracil
2434-53-9
|
US $1.00 / kg | 1kg | 99% | Customized | Career Henan Chemical Co |
-
- 6-Amino-1-methyluracil
2434-53-9
- US $0.00-0.00 / KG
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 6-AMino-1-Methyluracil
2434-53-9
- US $1.00 / KG
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- 6-Amino-1-methyluracil
2434-53-9
- US $1.00 / kg
- 99%
- Career Henan Chemical Co
