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Diisopropyl phosphite

CAS No.
1809-20-7
Chemical Name:
Diisopropyl phosphite
Synonyms
DIISOPROPYL PHOSPHONATE;Diisopropylphosphine oxide;Phosphonic acid, bis(1-methylethyl) ester;3P-230;(iPrO)2P(O)H;O,O-DiisopropyL;isopropylphosphonate;DI-I-PROPYLPHOSPHITE;Diisopropyl phosphit;Isopropyl phosphonate
CBNumber:
CB5671052
Molecular Formula:
C6H15O3P
Molecular Weight:
166.16
MDL Number:
MFCD00117905
MOL File:
1809-20-7.mol
MSDS File:
SDS
Last updated:2026-05-28 01:21:16

Diisopropyl phosphite Properties

Boiling point 71 °C (8 mmHg)
Density 0.997
refractive index 1.4065-1.4085
Flash point 69°C
storage temp. Inert atmosphere,Room Temperature
solubility Chloroform (Sparingly), Methanol (Sparingly)
form Liquid
Specific Gravity 1
color Clear colorless
Water Solubility soluble
Sensitive Moisture Sensitive
InChI InChI=1S/C6H15O3P/c1-5(2)8-10(7)9-6(3)4/h5-6,10H,1-4H3
InChIKey BLKXLEPPVDUHBY-UHFFFAOYSA-N
SMILES P(=O)(OC(C)C)OC(C)C
CAS DataBase Reference 1809-20-7(CAS DataBase Reference)
FDA UNII 676G4RQ6ND
NIST Chemistry Reference Phosphonic acid, di-isopropyl ester(1809-20-7)
EPA Substance Registry System Phosphonic acid, bis(1-methylethyl) ester (1809-20-7)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xn
Risk Statements  36/37/38-22
Safety Statements  37/39-26
RIDADR  3265
RTECS  SZ7660000
TSCA  TSCA listed
HS Code  29209085
Toxicity guinea pig,LC50,inhalation,9010mg/m3 (9010mg/m3),LUNGS, THORAX, OR RESPIRATION: OTHER CHANGESGASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDSBEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD,Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 29(11), Pg. 51, 1985.
NFPA 704
1
2 0

Diisopropyl phosphite price More Price(61)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical P0629 Diisopropyl Phosphite >98.0%(GC) 1809-20-7 25g $29 2026-04-30 Buy
TCI Chemical P0629 Diisopropyl Phosphite >98.0%(GC) 1809-20-7 500g $183 2026-04-30 Buy
Strem Chemicals 93-1527 Di-i-propylphosphite, min. 98% min.98% 1809-20-7 50g $76 2026-04-30 Buy
Strem Chemicals 93-1527 Di-i-propylphosphite, min. 98% min.98% 1809-20-7 250g $295 2026-04-30 Buy
TRC TRC-D459370-1G Diisopropyl Phosphite 1809-20-7 1g $59 2026-06-03 Buy
Product number Packaging Price Buy
P0629 25g $29 Buy
P0629 500g $183 Buy
93-1527 50g $76 Buy
93-1527 250g $295 Buy
TRC-D459370-1G 1g $59 Buy

Diisopropyl phosphite Chemical Properties, Uses, Production

Chemical Properties

clear colourless liquid, corrosive, soluble in organic solvents such as ethanol.

Uses

Diisopropyl phosphite is used as antiwear lubricant additive together with triphenyl thiophosphate on T8 steel/Al2O3 ceramics.

Preparation

Diisopropyl phosphite is prepared by directly reacting isopropanol with phosphorus trichloride.
3(CH3)2CHOH+PCl3→[(CH3)2CHO]2POH+2HCl↑+(CH3)2CHCl
At a ratio of 3:1 (mol), continuously feed 215kg/h of isopropanol and 150kg/h of phosphorus trichloride. When mixed, this results in a violent reaction that generates hydrogen chloride gas. This gas is quickly removed from the mixing pot using vacuum mercury. The crude ester produced is then heated in a falling film type spinner deacidification device and further deacidified. The resulting product is then cooled to below 40°C and obtained with a content of 92%-95% and a yield of 95%~98%.

Synthesis Reference(s)

Tetrahedron Letters, 29, p. 3327, 1988 DOI: 10.1016/0040-4039(88)85153-0

67-63-0
1809-20-7
Synthesis of Diisopropyl phosphite from Isopropyl alcohol
Global Suppliers ( 248)
Supplier Tel Email Country ProdList Advantage
Nanjing Yihua Biotechnology Co., Ltd 13429882898; 13429882898 1096323105@qq.com China 291 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TAIYUAN RHF CO.,LTD. +86 351 7031519 sales@RHFChem.com China 2334 56
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 marketing@accelachem.com China 10972 64
Shanghai Longsheng chemical Co.,Ltd. 58099637 13585536065 sales@shlschem.com China 9880 59
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64

View Latest Price from Diisopropyl phosphite manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Diisopropyl phosphite   pictures 2026-08-07 Diisopropyl phosphite
1809-20-7
$1.00 1KG 99% 200000KG Shaanxi Dideu Medichem Co. Ltd
Diisopropyl phosphite pictures 2026-06-30 Diisopropyl phosphite
1809-20-7
1KG 98.5% 10000KGS Shaanxi Dideu New Materials Co. Ltd
Diisopropyl phosphite pictures 2025-04-04 Diisopropyl phosphite
1809-20-7
1KG 98% 1ton Henan Aochuang Chemical Co.,Ltd.
Diisopropyl hydrogen phosphonate Isopropyl phosphonate Isopropyl phosphonate ((C3H7O)2HPO) isopropylphosphonate O,O-Diisopropyl phosphonate o,o-diisopropylphosphite o,o-diisopropylphosphonate Phosphonic acid, bis(1-methylethyl) ester phosphonicacid,bis(1-methylethyl)ester PHOSPHOROUS ACID DIISOPROPYL ESTER PHOSPHONIC ACID DIISOPROPYL ESTER 3P-230 DIISOPROPYL PHOSPHITE DIISOPROPYL HYDROGEN PHOSPHITE DI-I-PROPYLPHOSPHITE Di-i-propylphosphite,min.98% Dipropan-2-yl hydrogen phosphite Di-i-propylphosphite, min. 98% Phosphonic acid bis(1-methylethyl) Phosphonic acid diisopropyl Diisopropyl phosphite,98% Diipropylphosphitemincolorlessliq Diisopropoxyphosphine Oxide Diisopropyl Phosphonate Phosphonic Acid Diisopropyl Ester Phosphorous Acid Diisopropyl Ester Bis(propan-2-yl) phosphonate Diisopropyl phosphit Bis(2-propyl) phosphite O,O-DiisopropyL oxo-di(propan-2-yloxy)phosphonium DiisopropylPhosphite> dipropan-2-yl phosphite Diisopropylphosphine oxide DIISOPROPYL PHOSPHONATE (iPrO)2P(O)H 1809-20-7 C16H15O3P C6H15O3P C3H7O2POH CH32CHO2POH organophosphorus compound Miscellaneous Reagents bc0001