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Diisopropyl phosphite

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Diisopropyl phosphite Basic information
Product Name:Diisopropyl phosphite
Synonyms:Diisopropyl hydrogen phosphonate;Isopropyl phosphonate;Isopropyl phosphonate ((C3H7O)2HPO);isopropylphosphonate;O,O-Diisopropyl phosphonate;o,o-diisopropylphosphite;o,o-diisopropylphosphonate;Phosphonic acid, bis(1-methylethyl) ester
CAS:1809-20-7
MF:C6H15O3P
MW:166.16
EINECS:217-317-7
Product Categories:organophosphorus compound;Miscellaneous Reagents;bc0001
Mol File:1809-20-7.mol
Diisopropyl phosphite Structure
Diisopropyl phosphite Chemical Properties
Boiling point 71 °C (8 mmHg)
density 0.997
refractive index 1.4065-1.4085
Fp 69°C
storage temp. Inert atmosphere,Room Temperature
solubility Chloroform (Sparingly), Methanol (Sparingly)
form Liquid
Specific Gravity1
color Clear colorless
Water Solubility soluble
Sensitive Moisture Sensitive
InChIInChI=1S/C6H15O3P/c1-5(2)8-10(7)9-6(3)4/h5-6,10H,1-4H3
InChIKeyBLKXLEPPVDUHBY-UHFFFAOYSA-N
SMILESP(=O)(OC(C)C)OC(C)C
CAS DataBase Reference1809-20-7(CAS DataBase Reference)
NIST Chemistry ReferencePhosphonic acid, di-isopropyl ester(1809-20-7)
EPA Substance Registry SystemPhosphonic acid, bis(1-methylethyl) ester (1809-20-7)
Safety Information
Hazard Codes Xn
Risk Statements 36/37/38-22
Safety Statements 37/39-26
RIDADR 3265
RTECS SZ7660000
TSCA TSCA listed
HS Code 29209085
Toxicityguinea pig,LC50,inhalation,9010mg/m3 (9010mg/m3),LUNGS, THORAX, OR RESPIRATION: OTHER CHANGESGASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDSBEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD,Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 29(11), Pg. 51, 1985.
MSDS Information
ProviderLanguage
Diisopropyl phosphite English
ACROS English
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Diisopropyl phosphite Usage And Synthesis
Chemical Propertiesclear colourless liquid, corrosive, soluble in organic solvents such as ethanol.
UsesDiisopropyl phosphite is used as antiwear lubricant additive together with triphenyl thiophosphate on T8 steel/Al2O3 ceramics.
PreparationDiisopropyl phosphite is prepared by directly reacting isopropanol with phosphorus trichloride.
3(CH3)2CHOH+PCl3→[(CH3)2CHO]2POH+2HCl↑+(CH3)2CHCl
At a ratio of 3:1 (mol), continuously feed 215kg/h of isopropanol and 150kg/h of phosphorus trichloride. When mixed, this results in a violent reaction that generates hydrogen chloride gas. This gas is quickly removed from the mixing pot using vacuum mercury. The crude ester produced is then heated in a falling film type spinner deacidification device and further deacidified. The resulting product is then cooled to below 40°C and obtained with a content of 92%-95% and a yield of 95%~98%.
Synthesis Reference(s)Tetrahedron Letters, 29, p. 3327, 1988 DOI: 10.1016/0040-4039(88)85153-0
Tag:Diisopropyl phosphite(1809-20-7) Related Product Information
Triethyl phosphite Isopropyl chloroformate Triisopropyl phosphite Isopropyl acetate Isopropyl myristate Titanium tetraisopropanolate Triphenyl phosphite Isopropyl laurate Phosphorous acid tri-o-cresyl ester Di-tert-butyl phosphite Dibenzyl phosphite Diethyl phosphite Dimethyl phosphite GLYOXAL SODIUM BISULFITE Glycol sulfite Diphenyl phosphite Sodium phosphite-5-hydrate Monopotassium phosphite