ChemicalBook >> CAS DataBase List >>Cbz-beta-Amino-L-alanine

Cbz-beta-Amino-L-alanine

Cbz-beta-Amino-L-alanine structure

CAS No.: 35761-26-3

Chemical Name:: Cbz-beta-Amino-L-alanine

Synonyms: Z-DAP-OH;CBZ-DAP;Cbz-Dap-OH;Z-L-DAP-OH;H-DAP(Z)-OH;3-Amino-N-Cbz-L-alanine;Z-L-DAP;Z-DPR-OH;Z-Dap-0H;CBZ-L-DAP

CBNumber:: CB5677483

Molecular Formula:: C11H14N2O4

Molecular Weight:: 238.24

MDL Number:: MFCD00237345

MOL File:: 35761-26-3.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-07-15 13:06:51

Request For Quotation

Cbz-beta-Amino-L-alanine Properties

Melting point	~240 °C (dec.)
alpha	-39 º (1%, 1N HCl)
Boiling point	463.8±45.0 °C(Predicted)
Density	1.303±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Soluble in dilute acid.
form	Solid
pka	2.86±0.16(Predicted)
color	White
optical activity	[α]20/D 39±1°, c = 1% in 1 M HCl
Sensitive	Hygroscopic
BRN	4486950
Major Application	peptide synthesis
InChI	InChI=1S/C11H14N2O4/c12-6-9(10(14)15)13-11(16)17-7-8-4-2-1-3-5-8/h1-5,9H,6-7,12H2,(H,13,16)(H,14,15)/t9-/m0/s1
InChIKey	FOXRXVSTFGNURG-VIFPVBQESA-N
SMILES	C(O)(=O)[C@H](CN)NC(OCC1=CC=CC=C1)=O
CAS DataBase Reference	35761-26-3(CAS DataBase Reference)
UNSPSC Code	12352200
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302-H315-H319-H335

Precautionary statements

P261-P305+P351+P338

PPE

Eyeshields, Gloves, type N95 (US)

Safety Statements

22-24/25

WGK Germany

HS Code

2922.49.3700

HazardClass

IRRITANT

Storage Class

11 - Combustible Solids

NFPA 704

	0
0		1

Cbz-beta-Amino-L-alanine price More Price(73)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	96085	Z-Dap-OH ≥98.0% (NT)	35761-26-3	5g	$382	2023-06-20	Buy
TCI Chemical	A2471	(S)-3-Amino-2-(carbobenzoxyamino)propionic Acid >98.0%(HPLC)(T)	35761-26-3	1g	$19	2024-03-01	Buy
TCI Chemical	A2471	(S)-3-Amino-2-(carbobenzoxyamino)propionic Acid >98.0%(HPLC)(T)	35761-26-3	5g	$48	2024-03-01	Buy
Usbiological	C1102-02	Na-Carbobenzyloxy-b-amino-L-alanine (CBZ-L-b-Aminoalanine)	35761-26-3	1g	$340	2026-06-03	Buy
Usbiological	273262	N(alpha)-Z-L-2,3-Diaminopropionic acid Asreported	35761-26-3	5g	$412	2026-06-03	Buy

Product number	Packaging	Price	Buy
96085	5g	$382	Buy
A2471	1g	$19	Buy
A2471	5g	$48	Buy
C1102-02	1g	$340	Buy
273262	5g	$412	Buy

Cbz-beta-Amino-L-alanine Chemical Properties, Uses, Production

Chemical Properties

White Solid

Uses

Nalpha-Benzyloxycarbonyl-L-2,3-diaminopropionic acid is a important building block for the synthesis of peptides containing DAP residues, e.g. bleomycins, edeines, tuberactinomycins.

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

16947-84-5

35761-26-3

The general procedure for the synthesis of N(alpha)-Z-L-2,3-diaminopropionic acid from (S)-2-(((benzyloxy)carbonyl)amino)-3-((tert-butoxycarbonyl)amino)propionic acid is as follows: 50 g of (S)-N-benzyloxycarbonyl-N'-tert-butoxycarbonyl-2,3-diaminopropionic acid was dissolved in 500 mL of methylene chloride, followed by 50 mL of trifluoroacetic acid. The reaction mixture was stirred at 50 °C for the reaction and subsequently left at room temperature overnight. Upon completion of the reaction, the reaction mixture was concentrated to dryness by rotary evaporator and the evaporation process was repeated to completely remove the solvent.

References

[1] Collection of Czechoslovak Chemical Communications, 1976, vol. 41, p. 2969 - 2977
[2] Patent: CN108452321, 2018, A. Location in patent: Paragraph 0113; 0114; 0115; 0116

Cbz-beta-Amino-L-alanine Preparation Products And Raw materials

Raw materials

L-N-Cbz-3-N-Boc-Amino-alanine Trifluoroacetic acid Dichloromethane

Preparation Products

Z-Dap(Fmoc)-OH

Cbz-beta-Amino-L-alanine Suppliers

Global Suppliers ( 261)

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Linray Pharma Co.,Ltd	13651678121	sales@linraypharma.com	China	69	58
Tianjin Jiayi Biotechnology Co., LTD	13261917876 13261917876	503591062@qq.com	China	494	58
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	4006356688 18621169109	market03@meryer.com	China	40202	62
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15813	69
ChemFuture PharmaTech (Jiangsu) Ltd	5108538618	suger.wang@chemfuture.com	China	832	65
Alfa Aesar	400-6106006	saleschina@alfa-asia.com	China	30103	84
TCI (Shanghai) Development Co., Ltd.	021-67121386	Sales-CN@TCIchemicals.com	China	24512	81
Energy Chemical	400-0056266	sales8178@energy-chemical.com	China	44850	61
Capot Chemical Co., Ltd	+86 (0) 571 85 58 67 18		China	18187	66

Supplier	Advantage
Shanghai Linray Pharma Co.,Ltd	58
Tianjin Jiayi Biotechnology Co., LTD	58
J & K SCIENTIFIC LTD.	76
Meryer (Shanghai) Chemical Technology Co., Ltd.	62
3B Pharmachem (Wuhan) International Co.,Ltd.	69
ChemFuture PharmaTech (Jiangsu) Ltd	65
Alfa Aesar	84
TCI (Shanghai) Development Co., Ltd.	81
Energy Chemical	61
Capot Chemical Co., Ltd	66

View Latest Price from Cbz-beta-Amino-L-alanine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-07-15	Cbz-beta-Amino-L-alanine 35761-26-3		1KG	98%	1000kgs	Shaanxi Dideu New Materials Co. Ltd
2025-04-04	Cbz-beta-Amino-L-alanine 35761-26-3		1kg	98%	1Ton	Henan Aochuang Chemical Co.,Ltd.
2019-07-06	Cbz-beta-Amino-L-alanine 35761-26-3	$3.00	1KG	98%	100kg	Career Henan Chemical Co

Cbz-beta-Amino-L-alanine
35761-26-3
$0.00
98%
Shaanxi Dideu New Materials Co. Ltd

Cbz-beta-Amino-L-alanine
35761-26-3
98%
Henan Aochuang Chemical Co.,Ltd.

Cbz-beta-Amino-L-alanine
35761-26-3
$3.00
98%
Career Henan Chemical Co

Cbz-beta-Amino-L-alanine Spectrum

Cbz-beta-Amino-L-alanine(35761-26-3)¹HNMR

35761-26-3 (Cbz-beta-Amino-L-alanine) Related Search:

L-N-Cbz-3-N-Boc-Amino-alanine Fmoc-Lys(Boc)-OH Boc-Dap-OH Ac-His-OH H2O (S)-3-Amino-2-Cbz-amino-propionic acid tert-butyl ester

Z-Dap(Fmoc)-OH DL-2-Aminopropionic anhydride 2,3-Diaminopropionic acid L-2,3-Diaminopropionic acid L-Alanine

Cbz-beta-Amino-L-alanine (S)-Methyl 2-N-Cbz-3-N-Boc-propanoate Cbz-beta-amino-D-alanine (S)-N-4-Boc-N-1-Cbz-2-piperazine carboxylic acid Z-L-Dap(Boc)-OBn

N-alpha-Benzyloxycarbonyl-N-beta-allyloxycarbonyl-L-2,3-diaminopropionic acid dicyclohexylamine Methyl 2-(S)-[N-carbobenzyloxy]amino-3-aminopropionate, hydrochloride (S)-(-)-2-Oxo-1,5-imidazolidinedicarboxylic acid 1-benzyl ester

1of4

L-ALANINE, 3-AMINO-N-[(PHENYLMETHOXY)CARBONYL]- Z-Dap-OH >=98.0% (NT) Nα-Z-L-2,3-diaminopropionic acid≥ 98% (Assay) CBZ-BETA-AMINO-L-ALANINE CBZ-L-B-AMINOALANINE CBZ-L-DAP-OH H-DAP(Z)-OH 3-AMINO-2-BENZYLOXYCARBONYLAMINO-PROPIONIC ACID Z-L-2,3-DIAMINOPROPIONIC ACID Z-DPR-OH Z-ALPHA,BETA-DIAMINOPROPIONIC ACID (S)-3-AMINO-2-BENZYLOXYCARBONYLAMINO-PROPIONIC ACID N-BETA-CARBOBENZOXY-L-ALPHA, BETA-DIAMINOPROPIONIC ACID NA-BENZYLOXYCARBONYL-L-2,3-DIAMIOPROPIONIC ACID NA-CARBOBENZYLOXY-B-AMINO-L-ALANINE N-ALPHA-CARBOBENZOXY-L-ALPHA,BETA-DIAMINOPROPIONIC ACID N-ALPHA-BENZYLOXYCARBONYL-L-2,3-DIAMINOPROPIONIC ACID N-ALPHA-CBZ-L-2,3-DIAMINOPROPIONIC ACID N-ALPHA-Z-L-2,3-DIAMINOPROPIONIC ACID (2S)-3-amino-2-{[(benzyloxy)carbonyl]amino}propanoic acid 3-Amino-N-benzyloxycarbonyl-L-alanine CBZ-L-DAP Cbz-beta-Amino-L-ala NALPHA-Z-L-ALPHA,BETA-DIAMINOPROPIONIC ACID 3-AMINO-2-N-CBZ-L-ALANINE NA-BENZYLOXYCARBONYL-L-2,3-DIAMINOPROPIONICACID Z-L-DAP-OH CBZ-L-2,3- DIAMINOPROPIONIC ACID Cbz-L-2,3-DiaminopropionicAcid Nalpha-Carbobenzyloxy-beta-amino-L-alanine N-A-CBZ-L-2,3-DIAMINOPROPIONICACID (S)-3-amino-2-N-Cbz-propanoic acid CBZ-L--Aminoalanine Z-Dpr-OH, Nα-Z-L-2,3-Diaminopropionic acid N_α-Z-L-2,3-Diaminopropionic acid Nα-L-α,β- diaminopropionic acid (S)-3-amino-2-(benzyloxycarbonylamino)propanoic acid Nα-Carbobenzyloxy-β-amino-L-alanine (S)-3-AMino-2-(carbobenzoxyaMino)propionic Acid (S)-2-(BenzyloxycarbonylaMino)-3-aMinopropionic Acid 3-AMino-N-[(phenylMethoxy)carbonyl]-L-alanine (S)-Nalpha-Cbz-2,3-diaminopropionic Acid 3-Amino-N-(carbobenzoxy)-L-alanine 3-Amino-N-Cbz-L-alanine Z-Dap-OH Z-Dpr-OH Cbz-β-aMino-L-alanine Z-Dap-OH(Na-Boc-2,3-DiaMinopropionic acid) Z-L-DAP (S)-3-Amino-2-(carbobenzoxyamino)propionic Acid > (S)-3-Amino-2-(benzyloxycarbonylamino)-propanoicaci (S)-Nalpha-Cbz-2,3-diaminopropionic Acid 3-Amino-N-(carbobenzoxy)-L-alanine Cbz-beta-Amino-L-alanine USP/EP/BP Nα-Benzyloxycarbonyl-L-2,3-diamiopropionic Acid Discontinued See: C176175 (2S)-3-azaniumyl-2-(phenylmethoxycarbonylamino)propanoate Nα-Z-L-2,3-diaminopropionic acid (2S)-3-amino-2-benzyloxycarbonylaminopropionic acid Nα-L-α，β-Diaminopropionic acid Nα-Carbobenzyloxy-β-amino-L-alanine Z-Dap-0H N-Carbobenzyloxy--amino-L-alanine 3-Amino-N-Cbz-L-alanine