ChemicalBook >> CAS DataBase List >>Fmoc-Lys(Boc)-OH

Fmoc-Lys(Boc)-OH

Fmoc-Lys(Boc)-OH structure

CAS No.: 71989-26-9

Chemical Name:: Fmoc-Lys(Boc)-OH

Synonyms: FMOC-LYS(BOC)-OH;FMOC-LYS(BOC);FMOC-L-LYS(BOC)-OH;FMOC-D-LYS(BOC);(S)-2-((((9H-Fluoren-9-yl)Methoxy)carbonyl)aMino)-6-((tert-butoxycarbonyl)aMino)hexanoic acid;FMOC-L-LYS(BOC);fmoc-lys(boc)-o;Fmoc-Lys(Boc)-0H;N6-(TERT-BUTOXYCARBONYL)-N2-((9H-FLUOREN-9-YLMETHOXY)CARBONYL)-L-LYSINE;L-LYSINE, N6-[(1,1-DIMETHYLETHOXY)CARBONYL]-N2-[(9H-FLUOREN-9-YLMETHOXY)CARBONYL]-

CBNumber:: CB1451227

Molecular Formula:: C26H32N2O6

Molecular Weight:: 468.54

MDL Number:: MFCD00037138

MOL File:: 71989-26-9.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-06-24 18:39:39

Request For Quotation

Fmoc-Lys(Boc)-OH Properties

Melting point	130-135 °C (dec.)
alpha	-12 º (c=2,DMF 24 ºC)
Boiling point	570.69°C (rough estimate)
Density	1.2301 (rough estimate)
refractive index	-12 ° (C=1, DMF)
storage temp.	Store below +30°C.
solubility	Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka	3.88±0.21(Predicted)
form	Powder
color	White
optical activity	[α]20/D 12±1°, c = 1% in DMF
Water Solubility	Slightly soluble in water.
BRN	4217767
Stability	Stable. Incompatible with strong oxidizing agents.
Major Application	peptide synthesis
InChIKey	UMRUUWFGLGNQLI-QFIPXVFZSA-N
SMILES	CC(C)(C)OC(=O)NCCCC[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O
CAS DataBase Reference	71989-26-9(CAS DataBase Reference)
FDA 21 CFR	582.5411
UNSPSC Code	12352209
NACRES	NA.26

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362+P364-P403+P233-P501c

PPE

Eyeshields, Gloves, type N95 (US)

Hazard Codes

Safety Statements

24/25-36/37/39-27-26

WGK Germany

HS Code

29224999

Storage Class

11 - Combustible Solids

REACH Registrations

Active

NFPA 704

	0
1		0

Fmoc-Lys(Boc)-OH price More Price(127)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	8.52012	Fmoc-Lys(Boc)-OH Novabiochem?	71989-26-9	25g	$94.8	2026-04-30	Buy
Sigma-Aldrich	8.52012	Fmoc-Lys(Boc)-OH Novabiochem?	71989-26-9	100g	$232	2026-04-30	Buy
Sigma-Aldrich	8.52012	Fmoc-Lys(Boc)-OH Novabiochem?	71989-26-9	250g	$501	2026-04-30	Buy
Sigma-Aldrich	8.52012	Fmoc-Lys(Boc)-OH Novabiochem^®	71989-26-9	500 g	$919	2026-04-30	Buy
Sigma-Aldrich	8.52012	Fmoc-Lys(Boc)-OH Novabiochem?	71989-26-9	1kg	$1650	2026-04-30	Buy

Product number	Packaging	Price	Buy
8.52012	25g	$94.8	Buy
8.52012	100g	$232	Buy
8.52012	250g	$501	Buy
8.52012	500 g	$919	Buy
8.52012	1kg	$1650	Buy

Fmoc-Lys(Boc)-OH Chemical Properties, Uses, Production

Description

Fmoc-Lys(Boc)-OH (Na-Fmoc-Ne-Boc-L-lysine) has emerged as the standard Fmoc-Lys derivative used in peptide synthesis. The Boc group on the side chain is stable under basic conditions and remains in place even through many Fmoc deprotection cycles. The Boc group of Fmoc-Lys(Boc)-OH is readily removed with trifluoroacetic acid (TFA) during cleavage of the peptide product from Wang resin or Rink amide resin. It could self-assemble to sphere like morphology in all conditions irrespective of concentration and heating. To prepare the FAPI-04 dimer complex, this compound could used as a linker to conjugate two FAPI-04 structures by an amide reaction. After further modification, the product can perform cancer theranostics[1-2].

Chemical Properties

white to light yellow crystal powde

Uses

Fmoc-Lys(Boc)-OH can be used for:

The solid-phase synthesis of pentasubstituted dihydroimidazolylbutyl dihydroimidazol-3-ium salts by coupling with p-methylbenzhydrylamine (MBHA) resin.
Fmoc-based peptide synthesis of bis-naphthalene diimide, a threading intercalator.
Synthesis of ε-Boc-ε-(3,5-bis-trifluoromethyl-benzyl)-α-Fmoc-L-Lysine to be used as ¹⁹F NMR based screening tool.

Uses

Fmoc-Lys(Boc)-OH is used to prepare dimeric RGD peptide-paclitaxel conjugate as model for integrin-targeted drug delivery. It is also used to synthesize DOTA-conjugated multivalent cyclic-RGD peptide dendrimers for tumor targeting and imaging use.

reaction suitability

reaction type: Fmoc solid-phase peptide synthesis

References

[1] Gour N, et al. Controlled aggregation properties of modified single amino acids. ChemRxiv, 2021; 46.
[2] Zhong X, et al. Synthesis and Preclinical Evaluation of a Novel FAPI-04 Dimer for Cancer Theranostics. Molecular Pharmaceutics, 2023; 20: 2402–2414.

Fmoc-Lys(Boc)-OH Preparation Products And Raw materials

Raw materials

Preparation Products

Fmoc-Lys(Teoc)-OH Fmoc-L-HomoArg(Pbf)-OH Fmoc-Lys(biotin)-OH Fmoc-L-Lys(Dde)-OH Copper Peptide

(S)-2-(allyloxycarbonylaMino)-6-(tert-butoxycarbonylaMino)hexanoic acid Fmoc-Lys(Boc)-OPfp

1of2

Fmoc-Lys(Boc)-OH Suppliers

Global Suppliers ( 604)

Supplier	Tel	Email	Country	ProdList	Advantage
Suzhou Highfine Biotech Co., Ltd	0512-69209928 18796809688	zhouyingxiang@highfine.com	China	1846	58
Gansu Province Baishixing Pharmaceutical Co.,Ltd	15008395229 15008395229	zhangqing@gs-bsx.com	China	50	58
GL Biochem (Shanghai) Ltd	21-61263452 13641803416	ymbetter@glbiochem.com	China	9981	64
Lavem Chine Pharm Company	028-62070218 18190869852	sales@lavemc.com	China	214	67
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.	025-66113011 13913916777	cfzhang@aikonchem.com	China	19902	55
Chengdu Tachem Co., Ltd	028-61682518; 19983060238	sales@tachem.cn	China	102	58
shanghai Yanfeng biochemical technology Co.,LTD	17721070236 13611955358	yanfen2023@126.com	China	2995	58
Nanjing Machido Pharmaceutical Technology Co., Ltd.	19556085883	sales@machidopharma.com	China	393	58
GenChem & GenPharm (Changzhou) Co., Ltd.	0519-85720003 18861157602	410649415@qq.com	China	111	58
Zhangjiagang Specom Biochemical Co., Ltd.	512-0512-58992291,58992287 18606280718	admin@spbiochem.com	China	306	62

Supplier	Advantage
Suzhou Highfine Biotech Co., Ltd	58
Gansu Province Baishixing Pharmaceutical Co.,Ltd	58
GL Biochem (Shanghai) Ltd	64
Lavem Chine Pharm Company	67
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.	55
Chengdu Tachem Co., Ltd	58
shanghai Yanfeng biochemical technology Co.,LTD	58
Nanjing Machido Pharmaceutical Technology Co., Ltd.	58
GenChem & GenPharm (Changzhou) Co., Ltd.	58
Zhangjiagang Specom Biochemical Co., Ltd.	62

View Latest Price from Fmoc-Lys(Boc)-OH manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-17	N-Fmoc-N'-Boc-L-Lysine 71989-26-9	$5.00	1kg	≥99%	100mt/year	Jinan Finer Chemical Co., Ltd
2026-09-17	N-alpha-FMOC-Nepsilon-BOC-L-Lysine 71989-26-9		1KG	99.5%min	500KGS	WUHAN FORTUNA CHEMICAL CO., LTD
2026-09-17	Fmoc-L-Lys(Boc)-OH 71989-26-9		1kg	98%	1T	Sichuan HongRi Pharma-Tech Co.,Ltd

N-Fmoc-N'-Boc-L-Lysine
71989-26-9
$5.00
≥99%
Jinan Finer Chemical Co., Ltd

N-alpha-FMOC-Nepsilon-BOC-L-Lysine
71989-26-9
99.5%min
WUHAN FORTUNA CHEMICAL CO., LTD

Fmoc-L-Lys(Boc)-OH
71989-26-9
98%
Sichuan HongRi Pharma-Tech Co.,Ltd

Fmoc-Lys(Boc)-OH Spectrum

Fmoc-Lys(Boc)-OH(71989-26-9)¹HNMR Fmoc-Lys(Boc)-OH(71989-26-9)¹HNMR Fmoc-Lys(Boc)-OH(71989-26-9)FT-IR

71989-26-9 (Fmoc-Lys(Boc)-OH) Related Search:

9-Fluorenylmethyl chloroformate L-Lysine Fmoc-Aib-OH Cbz-beta-Amino-L-alanine Fmoc-OSu

Ac-His-OH H2O Di-tert-butyl ether FMOC-L-Methionine FMOC-L-Valine Fmoc-Asp(OtBu)-OH

FMOC-S-trityl-L-cysteine FMOC-Ala-OH FMOC-O-tert-Butyl-L-serine Fmoc-Gly-OH Fmoc-L-Tyr(propargyl)-OH

Fmoc-Asn(Trt)-OH Fmoc-tranexamic acid Fmoc-N-methyl-tranexamic acid

1of4

N^α-FMoc-N^ε-Boc-L-lysine N^e-Boc-N^a-FMoc-L-lysine, 98% ALPHA-FMOC-EPSILON-BOC-LYSINE Nα-Fmoc-Nε-Boc-L-lysine FMOC-D-LYSINE(BOC)-OH FMOC-L-LYS(TBOC)-OH FMOC-L-LYSINE(BOC) FMOC-L-LYSINE (TBOC) FMOC-N-EPSILON-BOC-D-LYSINE FMOC-N-EPSILON-BOC-L-LYSINE FMOC-LYS(BOC)-OH FMOC-LYSINE(BOC)-OH N_α-Fmoc-Nε-Boc-L-lysine Fmoc-(Boc)lysine Fmoc-Lys(Boc)-OH (N-Alpha-Fmoc-N-Epsilon-Boc-L-Lysine) N-alpha-FMOC-Nepsilo Nalpha-FMOC-Nepsilon-BOC-L-Lysine,99% L-LYSINE-ALPHA-N-FMOC, EPSILON-N-T-BOC Nepsilon-Boc-Nalpha-Fmoc-L-lysine Fmoc-Lys(Boc)-OH Fmoc-Iys(Boc)-OH (9H-Fluoren-9-yl)MethOxy]Carbonyl Lys(Boc)-OH Fomc-Lys(B ys(Boc)-OH FMoc-Lys(Boc)-OH >=98.0% (HPLC) Fmoc-Lys(Boc)-OH(CAS:71989-26-9) L-LYSINE-ALPHA-N-FMOC, EPSILON-N-T-BOC (13C6 L-LYSINE-ALPHA-N-FMOC, EPSILON-N-T-BOC (1-13C) Nα-Fmoc-Nε-Boc-L-lysine≥ 99.5% (HPLC, Chiral purity) N-α-FMOC-N-&epsi:-BOC-L-lysine N-ALPHA-FMOC-N-EPSILON-BOC-D-LYSINE N-ALPHA-FMOC-N-EPSILON-BOC-L-LYSINE N-ALPHA-FMOC-N-EPSILON-T-BOC-D-LYSINE N-ALPHA-FMOC-N-EPSILON-T-BOC-L-LYSINE N-ALPHA-FMOC-N-EPSILON-T-BUTYLOXYCARBONYL-D-LYSINE N-ALPHA-FMOC-N-EPSILON-T-BUTYLOXYCARBONYL-L-LYSINE N-ALPHA-FMOC-N-EPSILON-TERT-BOC-D-LYSINE N-ALPHA-FMOC-N-EPSILON-TERT-BOC-L-LYSINE N-ALPHA-FMOC-T-BOC-L-LYS N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-EPSILON-T-BUTYLOXYCARBONYL-L-LYSINE NEPSILON-tert-Butoxycarbonyl-NALPHA-9-fluorenylmethoxycarbonyl-L- lysine FMOC-N-(EPSILON)-BOC-L-LYSINE (FMOC-L-LYS(BOC)-OH) FMOC-N-E-BOC-L-LYSINE N-α-Fmoc-N-ε-t.-Boc-L-lysine L-Lysine-UL-13C6, 15N2-α-N-FMOC, ε-N-t-BOC L-Lysine-1-13C-α-N-FMOC, ε-N-t-BOC NA-FMOC-N-E-BOC-L-LYSINE N-ALPHA-9-FLUORENYLMETHOXYCARBONYL-N-EPSILON-T-BUTYLOXYCARBONYL-L-LYSINE N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-EPSILON-(TERT-BUTOXYCARBONYL)-L-LYSINE N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-EPSILON-T-BUTOXYCARBONYL-L-LYSINE N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-EPSILON-T-BUTOXYCARBONYL-D-LYSINE N-ALPHA-9-FLUORENYLMETHOXYCARBONYL-N-EPSILON-T-BUTYLOXYCARBONYL-D-LYSINE NALPHA-9-FLUORENYLMETHYLOXYCARBONYL-NEPSILON-TERT-BUTOXYCARBONYL-L-LYSINE N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-N-EPSILON-TERT-BUTYLOXYCARBONYL-L-LYSINE N(ALPHA)-(9-FLUROENYLMETHOXYCARBONYL)-N& NA-FMOC-N-EPSILON-T-BOC-L-LYSINE FMOC-LYS(BOC)-OH 98+% Fmoc-L-Lysine(Boc)-OH L-Lysine-1-13C-alpha-N-FMOC, epsilon-N-t-BOC