Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>1-Boc-6-amino-indazole

1-Boc-6-amino-indazole

1-Boc-6-amino-indazole Structure
1-Boc-6-amino-indazole structure
CAS No.
219503-81-8
Chemical Name:
1-Boc-6-amino-indazole
Synonyms
1-Boc-6-amino-indazole;1-Boc-1H-indazol-6-amine;6-Amino-1-Boc-1H-indazole;6-Amino-1H-indazole, N1-BOC;1-Boc-6-amino-1H-indazole,97%;6-Amino-1H-indazole, N1-BOC protected;6-AMINO-1-N-TERT-BUTOXYCARBONYL-1H-INDAZOLE;tert-butyl 6-amino-1H-indazole-1-carboxylate;6-AMINO-INDAZOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER;6-AMINO-1H-INDAZOLE-1-CARBOXYLIC ACID, 1,1 DIMETHYL ETHYL ESTER
CBNumber:
CB5717565
Molecular Formula:
C12H15N3O2
Molecular Weight:
233.27
MDL Number:
MFCD04114657
MOL File:
219503-81-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:53:40
Request For Quotation

1-Boc-6-amino-indazole Properties

Melting point 171-172℃
Boiling point 395.3±34.0 °C(Predicted)
Density 1.24±0.1 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka 2.52±0.10(Predicted)
form powder
color Yellow
Water Solubility Slightlysoluble in water.

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
HS Code  2933998090
NFPA 704
0
2 0

1-Boc-6-amino-indazole price More Price(57)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 265724 1-Boc-6-amino-indazole Asreported 219503-81-8 250mg $350 2026-06-03 Buy
Usbiological 265724 1-Boc-6-amino-indazole Asreported 219503-81-8 500mg $482 2026-06-03 Buy
Usbiological 265724 1-Boc-6-amino-indazole Asreported 219503-81-8 1g $831 2026-06-03 Buy
Usbiological 265724 1-Boc-6-amino-indazole Asreported 219503-81-8 2g $1165 2026-06-03 Buy
Usbiological 265724 1-Boc-6-amino-indazole Asreported 219503-81-8 5g $1659 2026-06-03 Buy
Product number Packaging Price Buy
265724 250mg $350 Buy
265724 500mg $482 Buy
265724 1g $831 Buy
265724 2g $1165 Buy
265724 5g $1659 Buy

1-Boc-6-amino-indazole Chemical Properties, Uses, Production

Uses

Used in the synthesis of chiral molecules.

Synthesis

tert-butyl 6-nitro-1H-indazole-1-carboxylate

219503-74-9

1-BOC-6-AMINO-INDAZOLE

219503-81-8

Step B: Preparation of tert-butyl 6-amino-1H-indazole-1-carboxylate: To a solution of tert-butyl 6-nitro-1H-indazole-1-carboxylate (0.88 g, 3.34 mmol) in methanol (20 mL) was added 10% Pd/C catalyst (0.355 g, 0.334 mmol). After displacing the air in the reaction system with nitrogen, the hydrogenation reaction was carried out under hydrogen (30 psi) atmosphere for 2 hours. After completion of the reaction, the reaction mixture was filtered through GF/F filter paper and the filtrate was concentrated to afford the target product tert-butyl 6-amino-1H-indazole-1-carboxylate (0.76 g, 98% yield). Mass spectrometry analysis (APCI-positive ion mode) showed [M+1]+ peak of 233.8.

References

[1] Patent: US2010/63066, 2010, A1. Location in patent: Page/Page column 35
[2] Journal of Medicinal Chemistry, 2002, vol. 45, # 4, p. 944 - 954
[3] Patent: US6372759, 2002, B1
[4] Bioorganic and Medicinal Chemistry, 2013, vol. 21, # 13, p. 3821 - 3830
[5] Asian Journal of Chemistry, 2014, vol. 26, # 22, p. 7539 - 7543

1-Boc-6-amino-indazole Preparation Products And Raw materials

Raw materials

tert-butyl 6-nitro-1H-indazole-1-carboxylate Methanol Hydrogen

Preparation Products

1-Boc-6-amino-indazole Suppliers

Global Suppliers ( 89)
Supplier Tel Email Country ProdList Advantage
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
ZEROSCHEM.CO.,LTD. 10-61256048 13810278579; sales@zeroschem.com China 1400 59
China DongFan Chemical Co.,LTD 86-0571-85151182 China 5681 66
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
Sphinx Scientific Laboratory (Tianjin) Co., Ltd. 022-66211289-843 13672102692 contact@sphinxpharm.com China 361 62
T&W GROUP 021-61551611 13296011611 contact@trustwe.com China 9884 58
Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd. +86-28-85122536 85324413 market@astatech.cn China 8016 55
Supplier Advantage
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Alfa Aesar 84
Pure Chemistry Scientific Inc. 62
Adamas Reagent, Ltd. 59
ZEROSCHEM.CO.,LTD. 59
China DongFan Chemical Co.,LTD 66
Shandong Xiya Chemical Co., Ltd 57
Sphinx Scientific Laboratory (Tianjin) Co., Ltd. 62
T&W GROUP 58
Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd. 55

1-Boc-6-amino-indazole Spectrum

1-BOC-6-AMINO-INDAZOLE(219503-81-8)1HNMR

219503-81-8 (1-Boc-6-amino-indazole) Related Search:

1H-Indazole-3-carboxylic acid, 6-broMo-, 1,1-diMethylethyl ester 1-Boc-6-bromo-indazole 1-Boc-6-amino-indazole 6-Cyanoamino-indazole-1-carboxylic acid tert-butyl ester 6-Amino-3-azetidin-1-ylmethyl-indazole-1-carboxylic acid tert-butyl ester
6-Amino-3-pyrrolidin-1-ylmethyl-indazole-1-carboxylic acid tert-butyl ester 6-Amino-3-morpholin-4-ylmethyl-indazole-1-carboxylic acid tert-butyl ester 6-Amino-3-(4-methyl-piperazin-1-ylmethyl)-indazole-1-carboxylic acid tert-butyl ester 6-Amino-3-diethylaminomethyl-indazole-1-carboxylic acid tert-butyl ester

1of2

6-AMINO-1H-INDAZOLE-1-CARBOXYLIC ACID, 1,1 DIMETHYL ETHYL ESTER 6-AMINO-1-N-TERT-BUTOXYCARBONYL-1H-INDAZOLE 6-AMINO-INDAZOLE-1-CARBOXYLIC ACID TERT-BUTYL ESTER tert-butyl 6-amino-1H-indazole-1-carboxylate 6-Amino-1H-indazole, N1-BOC protected 1H-Indazole-1-carboxylic acid, 6-aMino-, 1,1-diMethylethyl ester 6-Amino-1H-indazole, N1-BOC tert-Butyl 6-amino-1H-indazole-1-carboxylate, 6-Amino-1-(tert-butoxycarbonyl)-1H-indazole 1-Boc-1H-indazol-6-amine 1-Boc-6-amino-1H-indazole,97% 6-Amino-1-Boc-1H-indazole 1-Boc-6-amino-indazole 219503-81-8 Indazoles Building Blocks Indazole