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2-Nitroethanol

CAS No.
625-48-9
Chemical Name:
2-Nitroethanol
Synonyms
Ethanol, 2-nitro-;2-nitroethan-1-ol;nitroethanol;B-Nitroethanol;2-nitro-ethano;2-NITROETHANOL;2-Nitro-1-ethanol;beta-Nitroethanol;beta-nitroalcohol;2-Nitroethanol>
CBNumber:
CB5722396
Molecular Formula:
C2H5NO3
Molecular Weight:
91.07
MDL Number:
MFCD00007405
MOL File:
625-48-9.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 02:06:45

2-Nitroethanol Properties

Melting point -80 °C (lit.)
Boiling point 194 °C/765 mmHg (lit.)
Density 1.27 g/mL at 25 °C (lit.)
refractive index n20/D 1.445(lit.)
Flash point >230 °F
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility Chloroform, DMSO, Methanol (Sparingly)
form Liquid
pka 8.42±0.29(Predicted)
color Clear yellow
BRN 1633753
Henry's Law Constant 2.0×102 mol/(m3Pa) at 25℃, Raventos-Duran et al. (2010)
InChI InChI=1S/C2H5NO3/c4-2-1-3(5)6/h4H,1-2H2
InChIKey KIPMDPDAFINLIV-UHFFFAOYSA-N
SMILES C(O)C[N+]([O-])=O
CAS DataBase Reference 625-48-9(CAS DataBase Reference)
EWG's Food Scores 1
NIST Chemistry Reference Ethanol, 2-nitro-(625-48-9)
EPA Substance Registry System 2-Nitroethanol (625-48-9)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
target organs Respiratory system
PPE Eyeshields, Gloves, type ABEK (EN14387) respirator filter
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3
RTECS  KL9370000
3
HS Code  29055910
Storage Class 10 - Combustible liquids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
NFPA 704
1
2 0

2-Nitroethanol price More Price(62)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 146633 2-Nitroethanol 97% 625-48-9 5g $53.6 2026-04-30 Buy
Sigma-Aldrich 146633 2-Nitroethanol 97% 625-48-9 25g $255 2026-04-30 Buy
TCI Chemical N0368 2-Nitroethanol >93.0%(GC) 625-48-9 5g $137 2026-04-30 Buy
TCI Chemical N0368 2-Nitroethanol >93.0%(GC) 625-48-9 25g $460 2026-04-30 Buy
Usbiological 284991 2-Nitroethanol Asreported 625-48-9 5g $333 2026-06-03 Buy
Product number Packaging Price Buy
146633 5g $53.6 Buy
146633 25g $255 Buy
N0368 5g $137 Buy
N0368 25g $460 Buy
284991 5g $333 Buy

2-Nitroethanol Chemical Properties,Uses,Production

Preparation

2-Nitroethanol is an organic alcohol that can be prepared by reacting nitromethane and formaldehyde under alkaline conditions. Other preparation methods include the reaction of 2-iodoethanol with silver nitrite and the reaction of ethylene oxide with sodium nitrite.

Chemical Properties

Clear yellow liquid

Uses

2-Nitroethanol is an aliphatic β-nitro alcohol used as an in vivo therapeutic corneoscleral crosslinking agents with higher order nitroalcohol. It also functions as a crosslinking reagent for scieral tissue cross-linking of the eye cornea for treating keratoconus and post-surgical keratectasia.

General Description

Mobile dark brown-red liquid with a pungent odor.

Air & Water Reactions

Hygroscopic. Insoluble in water.

Reactivity Profile

2-Nitroethanol is incompatible with strong oxidizing agents, strong bases, acid chlorides and acid anhydrides. 2-Nitroethanol has exploded under vacuum distillation(attributed to the presence of peroxides or alkali).

Fire Hazard

2-Nitroethanol is probably combustible.

50-00-0
75-52-5
625-48-9
Synthesis of 2-Nitroethanol from Formaldehyde and Nitromethane
Global( 232)Suppliers
Supplier Tel Email Country ProdList Advantage
Beijing Stronger Science Co., Ltd. 0531-88924771 15614660963 elsa.hang@strongerscience.com China 10622 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
SelectLab Chemicals GmbH +49-(0)2383-919350 info@selectlab.de Germany 393 55
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Beijing Ouhe Technology Co., Ltd 13552068683 13522913783 2355560935@qq.com China 11777 60
JinYan Chemicals(ShangHai) Co.,Ltd. 13817811078 sales@jingyan-chemical.com China 9963 60

View Lastest Price from 2-Nitroethanol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Nitroethanol pictures 2020-01-03 2-Nitroethanol
625-48-9
$7.00 1KG 99% 100kg Career Henan Chemical Co
2-nitro-ethano beta-nitroalcohol beta-Nitroethanol beta-Nitroethyl alcohol 1-nitro-2-hydroxyethane 2-Nitroethanol, 85% (Assay) 2-Nitroethanol, pract., 85% 2-Nitroethanol,85% 2-NITROETHANOL: TECH., 80% B-Nitroethanol 2-Nitro-1-ethanol 2-NITROETHANOL β-Nitroethyl a1cohol 2-Nitroethanol,97% 2-Nitroethanol> 2-nitroethan-1-ol Ethanol, 2-nitro- nitroethanol 625-48-9 C2H5NO3 HOCH2CH2NO2 NO2CH2CH2OH O2NCH2CH2OH Building Blocks Alcohols C2 to C6 ALCOHOL Organic Building Blocks Oxygen Compounds Alcohols C2 to C6 Oxygen Compounds Miscellaneous