ETHYL 2-CYANOPYRIDINE-3-CARBOXYLATE
- CAS No.
- 75358-90-6
- Chemical Name:
- ETHYL 2-CYANOPYRIDINE-3-CARBOXYLATE
- Synonyms
- ethyl 2-cyanonicotinate;Ethyl 2-cyanonicotinate 97+%;2-Cyano-nicotinic acid ethyl ester;ETHYL 2-CYANOPYRIDINE-3-CARBOXYLATE;Ethyl 2-cyanopyridine-3-carboxylate 97%;3-(Ethoxycarbonyl)-2-pyridinecarbonitrile;2-cyano-3-pyridinecarboxylic acid ethyl ester;2-Cyanopyridine-3-carboxylic acid ethyl ester;3-Pyridinecarboxylic acid, 2-cyano-, ethyl ester
- CBNumber:
- CB5770771
- Molecular Formula:
- C9H8N2O2
- Molecular Weight:
- 176.17
- MDL Number:
- MFCD07368152
- MOL File:
- 75358-90-6.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 36/37/39 |
| WGK Germany | 3 |
| HS Code | 2933399990 |
ETHYL 2-CYANOPYRIDINE-3-CARBOXYLATE price More Price(14)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 791237 | Ethyl 2-cyanopyridine-3-carboxylate 97% | 75358-90-6 | 250mg | $72.3 | 2023-06-20 | Buy |
| TRC | B126370 | ethyl2-cyanonicotinate | 75358-90-6 | 50mg | $60 | 2021-12-16 | Buy |
| AK Scientific | W8273 | Ethyl2-cyanonicotinate | 75358-90-6 | 250mg | $120 | 2021-12-16 | Buy |
| Activate Scientific | AS16238 | Ethyl2-cyanonicotinate 97+% | 75358-90-6 | 5G | $420 | 2021-12-16 | Buy |
| Matrix Scientific | 139109 | Ethyl 2-cyanonicotinate 95%+ | 75358-90-6 | 5g | $1174 | 2021-12-16 | Buy |
ETHYL 2-CYANOPYRIDINE-3-CARBOXYLATE Chemical Properties,Uses,Production
Synthesis
557-21-1
1452-94-4
75358-90-6
To a solution of ethyl 2-chloropyridine-3-carboxylate (15.0 g, 81 mmol) in anhydrous N,N-dimethylacetamide (75 mL) was added zinc cyanide (5.71 g, 48.6 mmol), tris(dibenzylideneacetone)dipalladium (742 mg, 0.81 mmol), zinc powder (636 mg, 9.72 mmol), and 1,1'-bis(diphenylphosphinyl ) ferrocene (898 mg, 1.62 mmol). The reaction mixture was heated and stirred at 120 °C for 1 hour. After completion of the reaction, the mixture was cooled to room temperature and then partitioned between water (300 mL) and ether (150 mL). The organic and aqueous phases were separated by Celite filtration of the mixture. The aqueous phase was further extracted with ether (2 x 100 mL), all ether layers were combined, washed with saturated sodium chloride solution, dried over anhydrous sodium sulfate, filtered and concentrated under reduced pressure to give ethyl 2-cyanonicotinate (14.26 g, 100% yield).
References
[1] Patent: WO2004/46133, 2004, A1. Location in patent: Page 31
ETHYL 2-CYANOPYRIDINE-3-CARBOXYLATE Preparation Products And Raw materials
Raw materials
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Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou PBpharmaceutical R&D Co.,Ltd | 0519-83990708 | info@pbpharm.com | CHINA | 498 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 | shawn@hirisunpharm.com | CHINA | 9911 | 58 |
| Changzhou Guiding Bio-Tech. Co.,Ltd. | +86-519-519-86686860 +8618795626222 | ning@guiding-bio.com | China | 299 | 58 |
| Hu Bei Jiutian Bio-medical Technology CO.,Ltd | 027-88013699 17354350817 | Ryan@jiutian-bio.com | China | 5949 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| Cochemical Co. Ltd. | +86-029-86115547 +86-17791676824 | sales@cochemical.com | China | 3952 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42952 | 64 |
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