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Ethyl 2-chloronicotinate

CAS No.
1452-94-4
Chemical Name:
Ethyl 2-chloronicotinate
Synonyms
AVAC-001;oronicotinate;Ethyl 2-chloronicoti;Flunixin EP Impurity C;Ethyl 2-chloronicotite;ETHYL 2-CHLORONICOTINATE;Ehtyl 2-chloronicotinate;ethy-2-chloroisonicoitate;Ethyl2-Chloronicotinate>Flunixin Related CoMpound C
CBNumber:
CB4312224
Molecular Formula:
C8H8ClNO2
Molecular Weight:
185.61
MDL Number:
MFCD00674129
MOL File:
1452-94-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-04-24 14:58:15
Product description Number Pack Size Price
Flunixin impurity C European Pharmacopoeia (EP) Reference Standard Y0000445 55 mg $167
Flunixin Related Compound C Pharmaceutical Secondary Standard; Certified Reference Material PHR2413 50MG $620
Flunixin impurity C 1274631 50mg $1600
Flunixin impurity C European Pharmacopoeia (EP) Reference Standard Y0000445 y0000445 $153
Ethyl 2-Chloronicotinate >98.0%(GC) E0844 25g $38
More product size

Ethyl 2-chloronicotinate Properties

Melting point 68 C
Boiling point 78°C (0.1 mmHg)
Density 1.2445 g/cm3(Temp: 25 °C)
refractive index 1.5210-1.5250
storage temp. Keep in dark place,Sealed in dry,Room Temperature
pka -1.32±0.10(Predicted)
form Liquid
color Colorless to Light yellow to Light orange
Major Application pharmaceutical
InChI InChI=1S/C8H8ClNO2/c1-2-12-8(11)6-4-3-5-10-7(6)9/h3-5H,2H2,1H3
InChIKey PMIMPBYTPPRBGD-UHFFFAOYSA-N
SMILES C1(Cl)=NC=CC=C1C(OCC)=O
CAS DataBase Reference 1452-94-4(CAS DataBase Reference)
FDA UNII 7C4MMV3FW4
UNSPSC Code 41116107
NACRES NA.24

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H319
Precautionary statements  P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-37/39-60-37
WGK Germany  WGK 3
HazardClass  IRRITANT
HS Code  29333990
Storage Class 10 - Combustible liquids
Hazard Classifications Eye Irrit. 2
NFPA 704
1
2 0

Ethyl 2-chloronicotinate price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich Y0000445 Flunixin impurity C European Pharmacopoeia (EP) Reference Standard 1452-94-4 55 mg $167 2026-03-19 Buy
Sigma-Aldrich PHR2413 Flunixin Related Compound C Pharmaceutical Secondary Standard; Certified Reference Material 1452-94-4 50MG $620 2026-03-19 Buy
Sigma-Aldrich 1274631 Flunixin impurity C 1452-94-4 50mg $1600 2026-03-19 Buy
Sigma-Aldrich Y0000445 Flunixin impurity C European Pharmacopoeia (EP) Reference Standard 1452-94-4 y0000445 $153 2024-03-01 Buy
TCI Chemical E0844 Ethyl 2-Chloronicotinate >98.0%(GC) 1452-94-4 25g $38 2026-03-19 Buy
Product number Packaging Price Buy
Y0000445 55 mg $167 Buy
PHR2413 50MG $620 Buy
1274631 50mg $1600 Buy
Y0000445 y0000445 $153 Buy
E0844 25g $38 Buy

Ethyl 2-chloronicotinate Chemical Properties,Uses,Production

Chemical Properties

Light yellow liquid

Uses

Ethyl 2-chloronicotinate,is used as a pharmaceutical intermediate.

Synthesis Reference(s)

Tetrahedron, 51, p. 13177, 1995 DOI: 10.1016/0040-4020(95)00788-A

Synthesis

2-Chloropyridine-3-carboxylic acid (7.9 g) and thionyl chloride (45 ml) were heated for 3 hours in benzene (65 ml) under reflux. The reaction mixture was concentrated to leave an oil, which was added dropwise to ethanol (40 ml). The mixture was heated for a further one hour under reflux. The solvent was distilled, and the residue was dissolved in toluene. The solution was dried over anhydrous magnesium sulfate. The solvent was distilled to leave Ethyl 2-chloronicotinate (8.4 g, 90%) as a pale yellow oil.Ethyl 2-chloronicotinate

Ethyl 2-chloronicotinate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 324)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Chuanghai Biotechnology Co., Ltd
+8615350571055 Sibel@chuanghaibio.com China 8738 58
Shaanxi Dideu Medichem Co. Ltd
+8617392709771 1097@dideu.com China 3996 58
Henan Bao Enluo International TradeCo.,LTD
+86-17331933971 deasea125996@gmail.com China 2472 58
Hebei Zhuanglai Chemical Trading Co.,Ltd
+8613343047651 admin@zlchemi.com China 3692 58
Frapp's ChemicalNFTZ Co., Ltd.
+86 (576) 8169-6106 sales@frappschem.com China 880 50
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21591 55
career henan chemical co
+86-0371-86658258 +8613203830695 sales@coreychem.com China 29820 58
Standardpharm Co. Ltd.
86-714-3992388 overseasales1@yongstandards.com United States 14332 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49977 58

View Lastest Price from Ethyl 2-chloronicotinate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Ethyl 2-chloronicotinate pictures 2026-04-28 Ethyl 2-chloronicotinate
1452-94-4
US $0.00 / KG 200KG 98%min 30tons/month WUHAN FORTUNA CHEMICAL CO., LTD
Ethyl 2-chloronicotinate pictures 2026-03-20 Ethyl 2-chloronicotinate
1452-94-4
US $0.00-0.00 / KG 1KG 99% 20 mt Hebei Chuanghai Biotechnology Co., Ltd
Ethyl 2-chloronicotinate pictures 2025-12-24 Ethyl 2-chloronicotinate
1452-94-4
US $4656.00 / KG 1KG 99.0% 1000 tons Shaanxi Dideu Medichem Co. Ltd

Ethyl 2-chloronicotinate Spectrum

ETHYL 2-CHLORONICOTINATE ethyl 2-chloropyridine-3-carboxylate 2-CHLORONICOTINIC ACID ETHYL ESTER 2-Chloro-3-pyridinecarboxylic acid ethyl ester 2-Chloropyridine-3-carboxylic acid ethyl ester Ethyl 2-chloronicoti Ethyl 2-Chloro-3-pyridinecarboxylate 2-Chloronicotinic Acid Ethyl Ester Ethyl 2-Chloro-3-pyridinecarboxylate 2-Chloro-3-pyridinecarboxylic Acid Ethyl Ester 2-Chloronicotinate ethyl ester Ethyl 2-chloropyridine-3-carboxylate, 2-Chloro-3-(ethoxycarbonyl)pyridine Flunixin Related CoMpound C Ethyl 2-chloronicotinate, 99%, 99% Ethyl2-chloronicotinate,98% AVAC-001 oronicotinate Flunixin Meglumine Impurity 3(Flunixin Meglumine EP Impurity C) Flunixin Meglumine EP Impurity C Ethyl2-Chloronicotinate> Ethyl 2-Chloropyridine-3-carboxylat Flunixin EP Impurity C Flunixin impurity CQ: What is Flunixin impurity C Q: What is the CAS Number of Flunixin impurity C Q: What is the storage condition of Flunixin impurity C Q: What are the applications of Flunixin impurity C Flunixin Related Compound C (Ethyl 2-chloronicotinate) (1274631) Flunixin Meglumine Impurity C Flunixin USP Related Compound C ethy-2-chloroisonicoitate Ehtyl 2-chloronicotinate Ethyl 2-chloronicotinate, 98%min Ethyl 2-chloronicotite Flunixin Meglumine Impurity 6 1452-94-4 C8HBCINO2 pyridine series Pyridines Pharmaceutical Intermediates Pyridine Fluorobenzene