Ethyl 2-chloronicotinate
- CAS No.
- 1452-94-4
- Chemical Name:
- Ethyl 2-chloronicotinate
- Synonyms
- AVAC-001;oronicotinate;Ethyl 2-chloronicoti;Flunixin EP Impurity C;Ethyl 2-chloronicotite;ETHYL 2-CHLORONICOTINATE;Ehtyl 2-chloronicotinate;ethy-2-chloroisonicoitate;Ethyl2-Chloronicotinate>Flunixin Related CoMpound C
- CBNumber:
- CB4312224
- Molecular Formula:
- C8H8ClNO2
- Molecular Weight:
- 185.61
- MDL Number:
- MFCD00674129
- MOL File:
- 1452-94-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Flunixin impurity C European Pharmacopoeia (EP) Reference Standard | Y0000445 | 55 mg | $167 |
| Flunixin Related Compound C Pharmaceutical Secondary Standard; Certified Reference Material | PHR2413 | 50MG | $620 |
| Flunixin impurity C | 1274631 | 50mg | $1600 |
| Flunixin impurity C European Pharmacopoeia (EP) Reference Standard | Y0000445 | y0000445 | $153 |
| Ethyl 2-Chloronicotinate >98.0%(GC) | E0844 | 25g | $38 |
| More product size | |||
| Melting point | 68 C |
|---|---|
| Boiling point | 78°C (0.1 mmHg) |
| Density | 1.2445 g/cm3(Temp: 25 °C) |
| refractive index | 1.5210-1.5250 |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| pka | -1.32±0.10(Predicted) |
| form | Liquid |
| color | Colorless to Light yellow to Light orange |
| Major Application | pharmaceutical |
| InChI | InChI=1S/C8H8ClNO2/c1-2-12-8(11)6-4-3-5-10-7(6)9/h3-5H,2H2,1H3 |
| InChIKey | PMIMPBYTPPRBGD-UHFFFAOYSA-N |
| SMILES | C1(Cl)=NC=CC=C1C(OCC)=O |
| CAS DataBase Reference | 1452-94-4(CAS DataBase Reference) |
| FDA UNII | 7C4MMV3FW4 |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H319 | |||||||||
| Precautionary statements | P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-37/39-60-37 | |||||||||
| WGK Germany | WGK 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29333990 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| Hazard Classifications | Eye Irrit. 2 | |||||||||
| NFPA 704 |
|
Ethyl 2-chloronicotinate price More Price(29)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | Y0000445 | Flunixin impurity C European Pharmacopoeia (EP) Reference Standard | 1452-94-4 | 55 mg | $167 | 2026-03-19 | Buy |
| Sigma-Aldrich | PHR2413 | Flunixin Related Compound C Pharmaceutical Secondary Standard; Certified Reference Material | 1452-94-4 | 50MG | $620 | 2026-03-19 | Buy |
| Sigma-Aldrich | 1274631 | Flunixin impurity C | 1452-94-4 | 50mg | $1600 | 2026-03-19 | Buy |
| Sigma-Aldrich | Y0000445 | Flunixin impurity C European Pharmacopoeia (EP) Reference Standard | 1452-94-4 | y0000445 | $153 | 2024-03-01 | Buy |
| TCI Chemical | E0844 | Ethyl 2-Chloronicotinate >98.0%(GC) | 1452-94-4 | 25g | $38 | 2026-03-19 | Buy |
Ethyl 2-chloronicotinate Chemical Properties,Uses,Production
Chemical Properties
Light yellow liquid
Uses
Ethyl 2-chloronicotinate,is used as a pharmaceutical intermediate.
Synthesis Reference(s)
Tetrahedron, 51, p. 13177, 1995 DOI: 10.1016/0040-4020(95)00788-A
Synthesis
2-Chloropyridine-3-carboxylic acid (7.9 g) and thionyl chloride (45 ml) were heated for 3 hours in benzene (65 ml) under reflux. The reaction mixture was concentrated to leave an oil, which was added dropwise to ethanol (40 ml). The mixture was heated for a further one hour under reflux. The solvent was distilled, and the residue was dissolved in toluene. The solution was dried over anhydrous magnesium sulfate. The solvent was distilled to leave Ethyl 2-chloronicotinate (8.4 g, 90%) as a pale yellow oil.
Ethyl 2-chloronicotinate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +8617392709771 | 1097@dideu.com | China | 3996 | 58 |
| Henan Bao Enluo International TradeCo.,LTD | +86-17331933971 | deasea125996@gmail.com | China | 2472 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | +8613343047651 | admin@zlchemi.com | China | 3692 | 58 |
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 880 | 50 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21591 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29820 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14332 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49977 | 58 |
View Lastest Price from Ethyl 2-chloronicotinate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-04-28 | Ethyl 2-chloronicotinate
1452-94-4
|
US $0.00 / KG | 200KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
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2026-03-20 | Ethyl 2-chloronicotinate
1452-94-4
|
US $0.00-0.00 / KG | 1KG | 99% | 20 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
![]() |
2025-12-24 | Ethyl 2-chloronicotinate
1452-94-4
|
US $4656.00 / KG | 1KG | 99.0% | 1000 tons | Shaanxi Dideu Medichem Co. Ltd |
-

- Ethyl 2-chloronicotinate
1452-94-4
- US $0.00 / KG
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-

- Ethyl 2-chloronicotinate
1452-94-4
- US $0.00-0.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-

- Ethyl 2-chloronicotinate
1452-94-4
- US $4656.00 / KG
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
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