ChemicalBook >> CAS DataBase List >>Ethyl 2-chloronicotinate
Ethyl 2-chloronicotinate
- CAS No.
- 1452-94-4
- Chemical Name:
- Ethyl 2-chloronicotinate
- Synonyms
- AVAC-001;oronicotinate;Ethyl 2-chloronicoti;Flunixin EP Impurity C;Ethyl 2-chloronicotite;ETHYL 2-CHLORONICOTINATE;Ehtyl 2-chloronicotinate;ethy-2-chloroisonicoitate;Ethyl2-Chloronicotinate>Flunixin Related CoMpound C
- CBNumber:
- CB4312224
- Molecular Formula:
- C8H8ClNO2
- Molecular Weight:
- 185.61
- MDL Number:
- MFCD00674129
- MOL File:
- 1452-94-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-05-28 03:40:33
| Melting point | 68 C |
|---|---|
| Boiling point | 78°C (0.1 mmHg) |
| Density | 1.2445 g/cm3(Temp: 25 °C) |
| refractive index | 1.5210-1.5250 |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| pka | -1.32±0.10(Predicted) |
| form | Liquid |
| color | Colorless to Light yellow to Light orange |
| Major Application | pharmaceutical |
| InChI | InChI=1S/C8H8ClNO2/c1-2-12-8(11)6-4-3-5-10-7(6)9/h3-5H,2H2,1H3 |
| InChIKey | PMIMPBYTPPRBGD-UHFFFAOYSA-N |
| SMILES | C1(Cl)=NC=CC=C1C(OCC)=O |
| CAS DataBase Reference | 1452-94-4(CAS DataBase Reference) |
| FDA UNII | 7C4MMV3FW4 |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H319 | |||||||||
| Precautionary statements | P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-37/39-60-37 | |||||||||
| WGK Germany | WGK 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29333990 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| Hazard Classifications | Eye Irrit. 2 | |||||||||
| NFPA 704 |
|
Ethyl 2-chloronicotinate price More Price(62)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | Y0000445 | Flunixin impurity C European Pharmacopoeia (EP) Reference Standard | 1452-94-4 | 55 mg | $167 | 2026-04-30 | Buy |
| Sigma-Aldrich | PHR2413 | Flunixin Related Compound C Pharmaceutical Secondary Standard; Certified Reference Material | 1452-94-4 | 50MG | $620 | 2026-04-30 | Buy |
| Sigma-Aldrich | 1274631 | Flunixin impurity C | 1452-94-4 | 50mg | $1600 | 2026-04-30 | Buy |
| Sigma-Aldrich | Y0000445 | Flunixin impurity C European Pharmacopoeia (EP) Reference Standard | 1452-94-4 | y0000445 | $153 | 2024-03-01 | Buy |
| TCI Chemical | E0844 | Ethyl 2-Chloronicotinate >98.0%(GC) | 1452-94-4 | 25g | $38 | 2026-04-30 | Buy |
Ethyl 2-chloronicotinate Chemical Properties, Uses, Production
Chemical Properties
Light yellow liquid
Uses
Ethyl 2-chloronicotinate,is used as a pharmaceutical intermediate.
Synthesis Reference(s)
Tetrahedron, 51, p. 13177, 1995 DOI: 10.1016/0040-4020(95)00788-A
Synthesis
2-Chloropyridine-3-carboxylic acid (7.9 g) and thionyl chloride (45 ml) were heated for 3 hours in benzene (65 ml) under reflux. The reaction mixture was concentrated to leave an oil, which was added dropwise to ethanol (40 ml). The mixture was heated for a further one hour under reflux. The solvent was distilled, and the residue was dissolved in toluene. The solution was dried over anhydrous magnesium sulfate. The solvent was distilled to leave Ethyl 2-chloronicotinate (8.4 g, 90%) as a pale yellow oil.
Ethyl 2-chloronicotinate Preparation Products And Raw materials
Global Suppliers ( 328)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai URChem Limited | +86-021-50890968，021-50891159 +86-18601776121 | danny@urchem.com | China | 639 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TAIYUAN RHF CO.,LTD. | +86 351 7031519 | sales@RHFChem.com | China | 2334 | 56 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| ShangHai DEMO Chemical Co.,Ltd | 400-021-7337 2355568890 | sales@demochem.com | China | 2569 | 57 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10174 | 62 |
View Latest Price from Ethyl 2-chloronicotinate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-18 | Ethyl 2-chloronicotinate
1452-94-4
|
200KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-03-20 | Ethyl 2-chloronicotinate
1452-94-4
|
1KG | 99% | 20 mt | Hebei Chuanghai Biotechnology Co., Ltd | ||
 |
2025-12-24 | Ethyl 2-chloronicotinate
1452-94-4
|
$4656.00 | 1KG | 99.0% | 1000 tons | Shaanxi Dideu Medichem Co. Ltd |
-
- Ethyl 2-chloronicotinate
1452-94-4
- $0.00
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Ethyl 2-chloronicotinate
1452-94-4
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- Ethyl 2-chloronicotinate
1452-94-4
- $4656.00
- 99.0%
- Shaanxi Dideu Medichem Co. Ltd
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ETHYL 2-CHLORONICOTINATE
ethyl 2-chloropyridine-3-carboxylate
2-CHLORONICOTINIC ACID ETHYL ESTER
2-Chloro-3-pyridinecarboxylic acid ethyl ester
2-Chloropyridine-3-carboxylic acid ethyl ester
Ethyl 2-chloronicoti
Ethyl 2-Chloro-3-pyridinecarboxylate
2-Chloronicotinic Acid Ethyl Ester
Ethyl 2-Chloro-3-pyridinecarboxylate
2-Chloro-3-pyridinecarboxylic Acid Ethyl Ester
2-Chloronicotinate ethyl ester
Ethyl 2-chloropyridine-3-carboxylate, 2-Chloro-3-(ethoxycarbonyl)pyridine
Flunixin Related CoMpound C
Ethyl 2-chloronicotinate, 99%, 99%
Ethyl2-chloronicotinate,98%
AVAC-001
oronicotinate
Flunixin Meglumine Impurity 3（Flunixin Meglumine EP Impurity C）
Flunixin Meglumine EP Impurity C
Ethyl2-Chloronicotinate>
Ethyl 2-Chloropyridine-3-carboxylat
Flunixin EP Impurity C
Flunixin impurity CQ: What is
Flunixin impurity C Q: What is the CAS Number of
Flunixin impurity C Q: What is the storage condition of
Flunixin impurity C Q: What are the applications of
Flunixin impurity C
Flunixin Related Compound C (Ethyl 2-chloronicotinate) (1274631)
Flunixin Meglumine Impurity C
Flunixin USP Related Compound C
ethy-2-chloroisonicoitate
Ehtyl 2-chloronicotinate
Ethyl 2-chloronicotinate, 98%min
Ethyl 2-chloronicotite
Flunixin Meglumine Impurity 6
1452-94-4
C8HBCINO2
pyridine series
Pyridines
Pharmaceutical Intermediates
Pyridine
Fluorobenzene
