ChemicalBook >> CAS DataBase List >>E3 ligase Ligand 11

E3 ligase Ligand 11

E3 ligase Ligand 11 structure

CAS No.: 2357114-70-4

Chemical Name:: E3 ligase Ligand 11

Synonyms: cIAP1 ligand 2;E3 ligase Ligand 11;Benzyl ((S)-1-(((S)-1-Cyclohexyl-2-((S)-2-(4-(3-hydroxybenzoyl)thiazol-2-yl)pyrrolidin-1-yl)-2-oxoethyl)amino)-1-oxopropan-2-yl)(methyl)carbamate;benzyl N-[(1S)-1-{[(1S)-1-cyclohexyl-2-[(2S)-2-[4-(3-hydroxybenzoyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]-2-oxoethyl]carbamoyl}ethyl]-N-methylcarbamate;Carbamic acid, N-[(1S)-2-[[(1S)-1-cyclohexyl-2-[(2S)-2-[4-(3-hydroxybenzoyl)-2-thiazolyl]-1-pyrrolidinyl]-2-oxoethyl]amino]-1-methyl-2-oxoethyl]-N-methyl-, phenylmethyl ester

CBNumber:: CB58054705

Molecular Formula:: C34H40N4O6S

Molecular Weight:: 632.77

MDL Number:: MFCD32215339

MOL File:: 2357114-70-4.mol

Last updated:2025-04-18 09:51:11

Request For Quotation

E3 ligase Ligand 11 Properties

Boiling point	863.5±65.0 °C(Predicted)
Density	1.286±0.06 g/cm3(Predicted)
pka	8.78±0.10(Predicted)

E3 ligase Ligand 11 price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Biosynth	HUD11470	cIAP1 ligand 2	2357114-70-4	5mg	$1670.55	2026-06-04	Buy
Biosynth	HUD11470	cIAP1 ligand 2	2357114-70-4	10mg	$2672.8	2026-06-04	Buy
Biosynth	HUD11470	cIAP1 ligand 2	2357114-70-4	25mg	$5011.5	2026-06-04	Buy
Biosynth	HUD11470	cIAP1 ligand 2	2357114-70-4	50mg	$8018.5	2026-06-04	Buy

Product number	Packaging	Price	Buy
HUD11470	5mg	$1670.55	Buy
HUD11470	10mg	$2672.8	Buy
HUD11470	25mg	$5011.5	Buy
HUD11470	50mg	$8018.5	Buy

E3 ligase Ligand 11 Chemical Properties, Uses, Production

Uses

cIAP1 ligand 2 is the LCL161 derivative based IAP ligand. cIAP1 ligand 2 can be connected to the ABL ligand for protein by a linker to form SNIPER.

IC 50

cIAP1

References

[1] Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575. DOI:10.1021/acs.jmedchem.7b00168

E3 ligase Ligand 11 Preparation Products And Raw materials

Raw materials

Preparation Products

E3 ligase Ligand 11 Suppliers

Global Suppliers ( 10)

Supplier	Tel	Email	Country	ProdList	Advantage
Daicel Chiral Technologies (China)CO.,LTD	021-50460086-9 15921403865	han_yajun@dctc.daicel.com	China	7909	65
ShangHai Caerulum Pharma Discovery Co., Ltd.	18149758185 18149758185	sales-cpd@caerulumpharma.com	China	3493	58
Jilin Province Woda Biotechnology Co., Ltd.	13504435624	1927928688@qq.com	China	1644	58
TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	marketing@targetmol.com	United States	32431	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	9067	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58
Henan Mengtai Pharmaceutical Technology Co., Ltd	17634413542	1959525201@qq.com	China	9011	58
Affinity Linkers Ltd.	15841022315 15841022315	sales@affinitytech.cn	China	7039	58

Supplier	Advantage
Daicel Chiral Technologies (China)CO.,LTD	65
ShangHai Caerulum Pharma Discovery Co., Ltd.	58
Jilin Province Woda Biotechnology Co., Ltd.	58
TargetMol Chemicals Inc.	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	58
TargetMol Chemicals Inc.	58
Henan Mengtai Pharmaceutical Technology Co., Ltd	58
Affinity Linkers Ltd.	58

2357114-70-4 (E3 ligase Ligand 11) Related Search:

E3 ligase Ligand 12 Acetic acid, 2-[2-[2-[2-[3-[[2-[(2S)-1-[(2S)-2-cyclohexyl-2-[[(2S)-2-[[(1,1-dimethylethoxy)carbonyl]methylamino]-1-oxopropyl]amino]acetyl]-2-pyrrolidinyl]-4-thiazolyl]carbonyl]phenoxy]ethoxy]ethoxy]ethoxy]- E3 ligase Ligand-Linker Conjugates 37 E3 ligase Ligand-Linker Conjugates 41 E3 ligase Ligand-Linker Conjugates 33

E3 ligase Ligand-Linker Conjugates 36 E3 ligase Ligand-Linker Conjugates 39 E3 ligase Ligand-Linker Conjugates 34 E3 ligase Ligand-Linker Conjugates 38

1of2

cIAP1 ligand 2 E3 ligase Ligand 11 Benzyl ((S)-1-(((S)-1-Cyclohexyl-2-((S)-2-(4-(3-hydroxybenzoyl)thiazol-2-yl)pyrrolidin-1-yl)-2-oxoethyl)amino)-1-oxopropan-2-yl)(methyl)carbamate benzyl N-[(1S)-1-{[(1S)-1-cyclohexyl-2-[(2S)-2-[4-(3-hydroxybenzoyl)-1,3-thiazol-2-yl]pyrrolidin-1-yl]-2-oxoethyl]carbamoyl}ethyl]-N-methylcarbamate Carbamic acid, N-[(1S)-2-[[(1S)-1-cyclohexyl-2-[(2S)-2-[4-(3-hydroxybenzoyl)-2-thiazolyl]-1-pyrrolidinyl]-2-oxoethyl]amino]-1-methyl-2-oxoethyl]-N-methyl-, phenylmethyl ester 2357114-70-4