ChemicalBook >> CAS DataBase List >>Acetamide, N-[3-fluoro-5,6,7,8-tetrahydro-7-(hydroxyimino)-4-methyl-8-oxo-1-naphthalenyl]-

Acetamide, N-[3-fluoro-5,6,7,8-tetrahydro-7-(hydroxyimino)-4-methyl-8-oxo-1-naphthalenyl]-

Acetamide, N-[3-fluoro-5,6,7,8-tetrahydro-7-(hydroxyimino)-4-methyl-8-oxo-1-naphthalenyl]- structure

CAS No.: 182182-32-7

Chemical Name:: Acetamide, N-[3-fluoro-5,6,7,8-tetrahydro-7-(hydroxyimino)-4-methyl-8-oxo-1-naphthalenyl]-

Synonyms: Exatecan Intermediate 7;N-(3-Fluoro-7-(hydroxyimino)-4-methyl-8-oxo-5,6,7,8-tetrahydronaphthalen-1-yl)acetamide;Acetamide, N-[3-fluoro-5,6,7,8-tetrahydro-7-(hydroxyimino)-4-methyl-8-oxo-1-naphthalenyl]-;(Z)-N-(3-fluoro-7-(hydroxyimino)-4-methyl-8-oxo-5,6,7,8-tetrahydronaphthalen-1-yl)acetamide;N-[(7E)-3-Fluoro-7-(hydroxyimino)-4-methyl-8-oxo-5,6,7,8-tetrahydro-1-naphthalenyl]acetamide

CBNumber:: CB58375301

Molecular Formula:: C13H13FN2O3

Molecular Weight:: 264.25

MDL Number:

MOL File:: 182182-32-7.mol

MSDS File:: SDS

Last updated:2026-05-28 04:45:38

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Acetamide, N-[3-fluoro-5,6,7,8-tetrahydro-7-(hydroxyimino)-4-methyl-8-oxo-1-naphthalenyl]- Properties

Boiling point	536.4±50.0 °C(Predicted)
Density	1.41±0.1 g/cm3(Predicted)
form	Solid
pka	8.93±0.20(Predicted)
color	Light green to green

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS02,GHS07
Signal word	Danger
Hazard statements	H228-H315-H319
Precautionary statements	P240-P210-P241-P264-P280-P302+P352-P370+P378-P337+P313-P305+P351+P338-P362+P364-P332+P313

Acetamide, N-[3-fluoro-5,6,7,8-tetrahydro-7-(hydroxyimino)-4-methyl-8-oxo-1-naphthalenyl]- price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
aablocks	AA01RV9Q	Exatecan Intermediate 7 >98%	182182-32-7	25mg	$213	2026-05-31	Buy
aablocks	AA01RV9Q	Exatecan Intermediate 7 >98%	182182-32-7	50mg	$324	2026-05-31	Buy
aablocks	AA01RV9Q	Exatecan Intermediate 7 >98%	182182-32-7	100mg	$498	2026-05-31	Buy
ACHEMBLOCK	AD240803	N-(3-fluoro-7-(hydroxyimino)-4-methyl-8-oxo-5,6,7,8-tetrahydronaphthalen-1-yl)acetamide 95%	182182-32-7	100MG	$320	2026-05-27	Buy
ACHEMBLOCK	AD240803	N-(3-fluoro-7-(hydroxyimino)-4-methyl-8-oxo-5,6,7,8-tetrahydronaphthalen-1-yl)acetamide 95%	182182-32-7	1G	$1740	2026-05-27	Buy

Product number	Packaging	Price	Buy
AA01RV9Q	25mg	$213	Buy
AA01RV9Q	50mg	$324	Buy
AA01RV9Q	100mg	$498	Buy
AD240803	100MG	$320	Buy
AD240803	1G	$1740	Buy

Acetamide, N-[3-fluoro-5,6,7,8-tetrahydro-7-(hydroxyimino)-4-methyl-8-oxo-1-naphthalenyl]- Chemical Properties, Uses, Production

Uses

Exatecan Intermediate 7 is the intermediate of Exatecan (HY-13631) And Exatecan (DX-8951) is a DNA topoisomerase I inhibitor with an IC50 value of 2.2 μM (0.975 μg/mL) that can be used in cancer research. Exatecan Intermediate 7 can be used to synthesize Antibody-Drug Conjugates (ADCs).

IC 50

Camptothecins

References

[1] Kamihara, et al. Aminotetralone derivatives and process for producing the same. World Intellectual Property Organization, WO9626181 A1 1996-08-29.
[2] Mitsui I, et al. A new water-soluble camptothecin derivative, DX-8951f, exhibits potent antitumor activity against human tumors in vitro and in vivo. Jpn J Cancer Res. 1995 Aug;86(8):776-82. DOI:10.1111/j.1349-7006.1995.tb02468.x

Acetamide, N-[3-fluoro-5,6,7,8-tetrahydro-7-(hydroxyimino)-4-methyl-8-oxo-1-naphthalenyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

Acetamide, N-[3-fluoro-5,6,7,8-tetrahydro-7-(hydroxyimino)-4-methyl-8-oxo-1-naphthalenyl]- Suppliers

Global Suppliers ( 8)

Supplier	Tel	Email	Country	ProdList	Advantage
Bide Pharmatech Ltd.	400-164-7117 18317119277	product02@bidepharm.com	China	40000	60
Shanghai Haohong Pharmaceutical Co., Ltd.	400-8210725 4008210725	malulu@leyan.com	China	54996	58
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd	029-029-029-81148696 18161915376	1027@dideu.com	China	9989	58
Wuhan Yuxiang Medical Technology Co., Ltd.	13971275651	sales@whyxpharma.com	China	1831	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58
Henan Mengtai Pharmaceutical Technology Co., Ltd	17634413542	1959525201@qq.com	China	9011	58
Hebei Yaocheng Pharmaceutical Technology Co. Ltd	19903117580 19903117510	yc-eliu@yaochengph.com	China	9949	58

Supplier	Advantage
Bide Pharmatech Ltd.	60
Shanghai Haohong Pharmaceutical Co., Ltd.	58
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd	58
Wuhan Yuxiang Medical Technology Co., Ltd.	58
TargetMol Chemicals Inc.	58
Henan Mengtai Pharmaceutical Technology Co., Ltd	58
Hebei Yaocheng Pharmaceutical Technology Co. Ltd	58

182182-32-7 (Acetamide, N-[3-fluoro-5,6,7,8-tetrahydro-7-(hydroxyimino)-4-methyl-8-oxo-1-naphthalenyl]-) Related Search:

N-(3-Fluoro-4-methyl-8-oxo-5,6,7,8-tetrahydro-1-naphthyl)acetamide N,N'-(3-Fluoro-4-methyl-8-oxo-5,6,7,8-tetrahydronaphthalene-1,7-diyl)diacetamide N-(8-Amino-6-fluoro-5-methyl-1-oxo-1,2,3,4-tetrahydronaphthalen-2-yl)acetamide Acetamide, N-(3-fluoro-5,6,7,8-tetrahydro-8-oxo-1-naphthalenyl)- Exatecan intermediate 11

Acetamide, N-[(7Z)-3-chloro-5,6,7,8-tetrahydro-7-(hydroxyimino)-4-methyl-8-oxo-1-naphthalenyl]-

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Acetamide, N-[3-fluoro-5,6,7,8-tetrahydro-7-(hydroxyimino)-4-methyl-8-oxo-1-naphthalenyl]- Exatecan Intermediate 7 N-(3-Fluoro-7-(hydroxyimino)-4-methyl-8-oxo-5,6,7,8-tetrahydronaphthalen-1-yl)acetamide N-[(7E)-3-Fluoro-7-(hydroxyimino)-4-methyl-8-oxo-5,6,7,8-tetrahydro-1-naphthalenyl]acetamide (Z)-N-(3-fluoro-7-(hydroxyimino)-4-methyl-8-oxo-5,6,7,8-tetrahydronaphthalen-1-yl)acetamide 182182-32-7