Aminoguanidine
- CAS No.
- 79-17-4
- Chemical Name:
- Aminoguanidine
- Synonyms
- 1-Aminoguanidine;pimagedine;Aids030897;Aids-030897;Aminate base;Aminoguanidine;N-Aminoguanidine;Monoaminoguanidine;Aminoguanidine (ag);Ribavirin Impurity S
- CBNumber:
- CB5875700
- Molecular Formula:
- CH6N4
- Molecular Weight:
- 74.09
- MDL Number:
- MFCD00242587
- MOL File:
- 79-17-4.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 182-185 °C (decomp) |
|---|---|
| Boiling point | 159.5±23.0 °C(Predicted) |
| Density | 1.72±0.1 g/cm3(Predicted) |
| refractive index | 1.6660 (estimate) |
| pka | 11.08±0.70(Predicted) |
| FDA UNII | SCQ4EZQ113 |
Aminoguanidine price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | P445105 | Pimagedinehydrochloride | 79-17-4 | 10mg | $45 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 18895 | Pimagedine 98% | 79-17-4 | 5mg | $950 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000371 | AMINOGUANIDINE 95.00% | 79-17-4 | 25G | $1146.05 | 2021-12-16 | Buy |
Aminoguanidine Chemical Properties,Uses,Production
Chemical Properties
Aminoguanidine [CAS: 79-17-4], CH6N4, Mr 74.09, is a base that forms salts with both inorganic and organic acids. It is soluble in water and ethanol. Free aminoguanidine is stable for only a short time; therefore, it is marketed in the form of its stable salts. Commercially, aminoguanidine is offered as the bicarbonate salt [2582-30-1], a white powder of usually 99 % assay. The water solubility at room temperature is low (< 5 g/L). It is offered by most world-scale hydrazine producers (→Hydrazine). Other salts can be prepared from the bicarbonate by reaction with acid.
Chemical Properties
Aminoguanidine is prepared from hydrazine
and aqueous cyanamide solution. Processes
based on the reduction of nitroguanidine have
no industrial significance.
Uses
Inhibitor (advanced glycosylation end-product formation).
Definition
ChEBI: Aminoguanidine is a one-carbon compound whose unique structure renders it capable of acting as a derivative of hydrazine, guanidine or formamide. It has a role as an EC 1.4.3.4 (monoamine oxidase) inhibitor and an EC 1.14.13.39 (nitric oxide synthase) inhibitor. It is a member of guanidines and a one-carbon compound.
Enzyme inhibitor
This substituted hydrazine (FWhydrochloride = 110.55 g/mol; CAS 79-17-4), also named pimagedine, is a strong inhibitor of diamine oxidases as well as nitric oxide synthase. Note that aminoguanidine also inhibits the formation of advanced glycosylation end-products, reportedly by reacting with and trapping Amadori rearrangement-derived fragmentation products in solution. In view of this property, aminoguanidine has often been used to treat complications associated with chronic diabetes. Target(s): amine oxidase (copper-containing), or diamine oxidase; methylamine dehydrogenase; tryptophan tryptophylquinone enzymes; nitric-oxide synthase; b-fructofuranosidase, or invertase; monoamine oxidase, or amine oxidase; histidine decarboxylase; aldose reductase; catalase; formation of advanced glycosylation end products; adenosylmethionine decarboxylase; arginine deaminase; arginine kinase; aspartate aminotransferase; histamine N-methyltransferase.
Aminoguanidine Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai T&W Pharmaceutical Co., Ltd. | +86 21 61551611 | China | 9874 | 58 | |
| Quality Control Solutions Ltd. | 0755-66853366 13670046396 | orders@qcsrm.com | China | 18188 | 56 |
| Finetech Industry Limited | 027-87465837 19945049750 | sales@finetechnology-ind.com | China | 9331 | 58 |
| Puripharm Co., Ltd. | 0572-2745768-1 13167223168;13167223168 | sales@puripharm.com | China | 299 | 65 |
| Macheng jinxin biotechnology co., LTD | 18271582018 | 1126319697@qq.com | China | 1525 | 58 |
| Finetech Industry Limited | +86-27-8746-5837 +86-18627785180 | info@finetechnology-ind.com | China | 9533 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34526 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 17705817739 | info@dycnchem.com | China | 52693 | 58 |
| AFINE CHEMICALS LIMITED | +86-571-85134551 +86-18958018566 | info@afinechem.com | China | 15030 | 58 |
| Qingdao haohai anjie pharmaceutical technology co., ltd. | 156-6622-8711 18639325623 | chen.wanglin@hmgj.group | China | 1900 | 58 |
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