Aminoguanidine hydrochloride
- CAS No.
- 1937-19-5
- Chemical Name:
- Aminoguanidine hydrochloride
- Synonyms
- Aminoguanidine HCL;2-aminoguanidine hydrochloride;GUANYLHYDRAZINEHCL;AMINOGUANIDINE SALT;Aminoguanidine salts;CP-12009-18 tartrate;Aminoguanidine hydrochoride;amino-guanidinhydrochloride;Aminoguanadine hydrochloride;AMINOGUANIDINE HYDROCHLORIDE
- CBNumber:
- CB7497900
- Molecular Formula:
- CH7ClN4
- Molecular Weight:
- 110.54608
- MDL Number:
- MFCD00039074
- MOL File:
- 1937-19-5.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Aminoguanidine hydrochloride ≥98% | 396494 | 25g | $77.2 |
| Aminoguanidine hydrochloride ≥98% | 396494 | 100g | $235 |
| Aminoguanidine Hydrochloride >98.0%(T) | A1129 | 25g | $57 |
| Aminoguanidine Hydrochloride >98.0%(T) | A1129 | 100g | $123 |
| Aminoguanidine (hydrochloride) ≥98% | 81530 | 10g | $28 |
| More product size | |||
| Melting point | 162-166 °C(lit.) |
|---|---|
| vapor pressure | 0Pa at 25℃ |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | Completely soluble in water |
| form | Crystals |
| color | White to off-white |
| Water Solubility | 506.7g/L at 20℃ |
| Merck | 13,440 |
| BRN | 3909606 |
| Cosmetics Ingredients Functions | SKIN CONDITIONING |
| InChI | InChI=1S/CH6N4.ClH/c2-1(3)5-4;/h4H2,(H4,2,3,5);1H |
| InChIKey | UBDZFAGVPPMTIT-UHFFFAOYSA-N |
| SMILES | N(N)C(=N)N.[H]Cl |
| LogP | -3.55 at 20℃ |
| CAS DataBase Reference | 1937-19-5(CAS DataBase Reference) |
| FDA UNII | A2Z7G2RGAH |
| EPA Substance Registry System | Hydrazinecarboximidamide, monohydrochloride (1937-19-5) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H317-H411 | |||||||||
| Precautionary statements | P261-P272-P273-P280-P302+P352-P333+P313 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | ME8430000 | |||||||||
| F | 10-21 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29280000 | |||||||||
| Storage Class | 13 - Non Combustible Solids | |||||||||
| Hazard Classifications | Aquatic Chronic 2 Skin Sens. 1B |
|||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
Aminoguanidine hydrochloride price More Price(64)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 396494 | Aminoguanidine hydrochloride ≥98% | 1937-19-5 | 25g | $77.2 | 2026-04-30 | Buy |
| Sigma-Aldrich | 396494 | Aminoguanidine hydrochloride ≥98% | 1937-19-5 | 100g | $235 | 2026-04-30 | Buy |
| TCI Chemical | A1129 | Aminoguanidine Hydrochloride >98.0%(T) | 1937-19-5 | 25g | $57 | 2026-04-30 | Buy |
| TCI Chemical | A1129 | Aminoguanidine Hydrochloride >98.0%(T) | 1937-19-5 | 100g | $123 | 2026-04-30 | Buy |
| Cayman Chemical | 81530 | Aminoguanidine (hydrochloride) ≥98% | 1937-19-5 | 10g | $28 | 2026-04-30 | Buy |
Aminoguanidine hydrochloride Chemical Properties,Uses,Production
Description
Aminoguanidine is equipotent to L-
Chemical Properties
white to off-white crystals
Uses
antitussive
Uses
a-Glucosidase inhibitor; hydroxyethyl derivative of 1-deoxynojirimycin
Uses
Aminoguanidine hydrochloride may be employed as nitric oxide synthase (NOS) inhibitor to investigate its effect on the reduction of alveolar bone loss in ligature induced periodontitis in rats. It may be used in the synthesis of 5-guanylhydrazone derivatives, having antibacterial activity against antibacterial activity against both Escherichia coli and Staphylococcus aureus.
Biological Functions
It is reported that aminoguanidine hydrochloride has two important biological effects. Firstly, it is effective for the prevention of formation of advanced glycation endproducts (AGEs) associated with pathogenesis of secondary complications to diabetes and with cardiovascular changes in aging. Aminoguanidine hydrochloride reacts rapidly with in vivo glycation α,β-dicarbonyl products such as methylglyoxal, glyoxal, and 3-deoxyglucosone to prevent the formation of AGEs.
Secondly, it inhibits of the individual isoforms of nitric oxide synthase (iNOS) which is one of three key enzymes generating nitric oxide (NO) from L-arginine. iNOS-derived nitric oxide plays an important role in numerous physiological (e.g. blood pressure regulation) and pathophysiological (e.g. inflammation) conditions.
General Description
Aminoguanidine hydrochloride has been reported in a study as inhibitor of animal nitric oxide (NO)-synthase. Crystal structure of aminoguanidine hydrochloride has been investigated by Fourier and least squares method. Its crystals were monoclinic and the guanidine part of the aminoguanidinium ion is planar.
Flammability and Explosibility
Not classified
Biochem/physiol Actions
Inhibits both constitutive and inducible nitric oxide synthetase.
References
[1] JOLY G.A. Effects of NG-Methyl-L-arginine, NG-Nitro-L-arginine, and Aminoguanidine on Constitutive and Inducible Nitric Oxide Synthase in Rat Aorta[J]. Biochemical and biophysical research communications, 1994, 199 1: Pages 147-154. DOI: 10.1006/bbrc.1994.1207
[2] J A CORBETT M L M. Selective inhibition of inducible nitric oxide synthase by aminoguanidine.[J]. Methods in enzymology, 1996, 268: 398-408. DOI: 10.1016/s0076-6879(96)68042-2
[3] H. RUETTEN C. T. Prevention of the Expression of Inducible Nitric Oxide Synthase by Aminoguanidine or Aminoethyl-Isothiourea in Macrophages and in the Rat[J]. Biochemical and biophysical research communications, 1996, 225 2: Pages 525-530. DOI: 10.1006/bbrc.1996.1206
Aminoguanidine hydrochloride Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jiaxing Dongliang Pharmaceutical Technology Co.,Ltd. | +86-0573-84772883 +86-18905731109 | hujidong@hailunchem.com | China | 7 | 58 |
| Wuwei hailun New Material Technology Co., Ltd. | +86-0935-5322366 +86-13605736198 | hailunchem@vip.163.com | China | 7 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +86-17732866630 | mina@chuanghaibio.com | China | 18112 | 58 |
| airuikechemical co., ltd. | +86-18353166132 | sales02@airuikechemical.com | China | 983 | 58 |
| Hebei Zhuanglai Chemical Trading Co.,Ltd | 13343047651 | admin@zlchemi.com | China | 3689 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21531 | 55 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5898 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14320 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19935 | 58 |
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29780 | 58 |
Related Qustion
Ask a questionView Lastest Price from Aminoguanidine hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-27 | Aminoguanidine hydrochloride
1937-19-5
|
$35.00-81.00 | 99.80% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-07-27 | Aminoguanidine hydrochloride
1937-19-5
|
$35.00-81.00 | 99.80% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-07-27 | Aminoguanidine hydrochloride
1937-19-5
|
$35.00-81.00 | 99.80% | 10g | TargetMol Chemicals Inc. |
-
- Aminoguanidine hydrochloride
1937-19-5
- $35.00-81.00
- 99.80%
- TargetMol Chemicals Inc.
-
- Aminoguanidine hydrochloride
1937-19-5
- $35.00-81.00
- 99.80%
- TargetMol Chemicals Inc.
-
- Aminoguanidine hydrochloride
1937-19-5
- $35.00-81.00
- 99.80%
- TargetMol Chemicals Inc.
