propionamidine hydrochloride
- CAS No.
- 3599-89-1
- Chemical Name:
- propionamidine hydrochloride
- Synonyms
- Propanamidine HCl;Propanimidamide, HCl;Propionamidine hydrochL;propanimidamide chloride;propionamidine acetic acid;Propioamidine hydrochloride;PROPANAMIDINE HYDROCHLORIDE;Propanamidine hydrochloride 97%;PropaniMidaMide,Monohydrochloride (9CI);Propionamidine hydrochloride, Propanimidamide hydrochloride
- CBNumber:
- CB5885172
- Molecular Formula:
- C3H9ClN2
- Molecular Weight:
- 108.56996
- MDL Number:
- MFCD00233938
- MOL File:
- 3599-89-1.mol
- MSDS File:
- SDS
| Melting point | 298.5 °C |
|---|---|
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| color | White to Off-White |
| InChI | InChI=1S/C3H8N2.ClH/c1-2-3(4)5;/h2H2,1H3,(H3,4,5);1H |
| InChIKey | DFWRZHZPJJAJMX-UHFFFAOYSA-N |
| SMILES | C(=N)(N)CC.Cl |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
| HS Code | 2925290090 |
propionamidine hydrochloride price More Price(48)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | TRC-P839090-5G | Propioamidine Hydrochloride | 3599-89-1 | 5g | $220 | 2026-06-03 | Buy |
| TRC | TRC-P839090-250MG | Propioamidine Hydrochloride | 3599-89-1 | 250mg | $65 | 2026-06-03 | Buy |
| TRC | TRC-P839090-1G | Propioamidine Hydrochloride | 3599-89-1 | 1g | $84 | 2026-06-03 | Buy |
| Apolloscientific | OR200136 | Propanamidine hydrochloride 95% | 3599-89-1 | 250mg | $35 | 2026-06-04 | Buy |
| Apolloscientific | OR200136 | Propanamidine hydrochloride 95% | 3599-89-1 | 1g | $41 | 2026-06-04 | Buy |
propionamidine hydrochloride Chemical Properties, Uses, Production
Uses
Propioamidine Hydrochloride acts as a reagent in the synthetic preparation of guanidine.
Synthesis
107-12-0
3599-89-1
The general procedure for synthesizing propionamidine hydrochloride from propionitrile was as follows: with reference to the preparation of propionamide hydrochloride in Example 28, hydrogen chloride gas was passed into a solution of propionitrile (10 g, 142 mmol) in ethanol (8.4 mL) until the total amount was increased by 7.9 g, and the reaction mixture was stirred at room temperature for 21.5 hours. Upon completion of the reaction, the solvent was removed by concentration under reduced pressure, the residue was suspended in ethanol (5.5 mL) and the suspension was cooled to -10 °C. A methanol solution of 8N ammonia (17.8 mL) was slowly added to the cooled suspension and stirring was continued for 28 hours at room temperature. At the end of the reaction, the insoluble material was removed by filtration, and the filtrate was concentrated under reduced pressure to give propionamidine hydrochloride (10.8 g, 70% yield) in white crystal form. The product was characterized by 1H NMR (300 MHz, DMSO-d6): δ 1.17 (3H, t, J = 7.6 Hz), 2.40 (2H, q, J = 7.7 Hz), 8.77 (2H, br s), 9.07 (2H, br s).
References
[1] Patent: EP2471793, 2012, A1. Location in patent: Page/Page column 48
[2] Bioorganic and Medicinal Chemistry, 2015, vol. 23, # 15, p. 4777 - 4791
[3] Patent: WO2011/130628, 2011, A1. Location in patent: Page/Page column 177-178
[4] Patent: US2013/102595, 2013, A1. Location in patent: Paragraph 0370; 0371
[5] Patent: JP2015/187145, 2015, A. Location in patent: Paragraph 0324
propionamidine hydrochloride Preparation Products And Raw materials
Raw materials
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Preparation Products
propionamidine hydrochloride Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Increland Biotechnology Co.,Ltd | 18428181580 18428181580 | chenxing@cyclobiotech.com | China | 284 | 58 |
| Shanghai Boyle Chemical Co., Ltd. | 021-50182298 021-50180596 | sales@boylechem.com | China | 2202 | 55 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Beijing HwrkChemical Technology Co., Ltd | 89508211 18501085097 | sales.bj@hwrkchemical.com | China | 9407 | 55 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Shanghai Longsheng chemical Co.,Ltd. | 58099637 13585536065 | sales@shlschem.com | China | 9880 | 59 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| China DongFan Chemical Co.,LTD | 86-0571-85151182 | China | 5681 | 66 | |
| Chembon Pharmaceutical Co., Ltd. | 028-84252981 18583719936 | sales@chembon.com.cn | China | 854 | 64 |
View Latest Price from propionamidine hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-06-30 | propionamidine hydrochloride
3599-89-1
|
1kg | 98% | 1000kg | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2020-01-09 | propionamidine hydrochloride
3599-89-1
|
$1.00 | 1KG | 99% | 200kg | Career Henan Chemical Co |
-
- propionamidine hydrochloride
3599-89-1
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- propionamidine hydrochloride
3599-89-1
- $1.00
- 99%
- Career Henan Chemical Co
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