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3-(2-nitrophenyl)propionic acid

CAS No.
2001-32-3
Chemical Name:
3-(2-nitrophenyl)propionic acid
Synonyms
3-(2-Nitrophenyl);2-Nitrobenzenepropanoic acid;3-(2-Nitrophenyl)propionsure;3-(2-nitrophenyl)propionic acid;3-(2-Nitrophenyl)propanoic acid;Benzenepropanoic acid, 2-?nitro-;2-(2-Carboxyethyl)-1-nitrobenzene
CBNumber:
CB5930409
Molecular Formula:
C9H9NO4
Molecular Weight:
195.17
MDL Number:
MFCD00130002
MOL File:
2001-32-3.mol
Last updated:2025-08-08 17:45:00

3-(2-nitrophenyl)propionic acid Properties

Melting point 115 °C
Boiling point 331.83°C (rough estimate)
Density 1.3544 (rough estimate)
refractive index 1.5700 (estimate)
storage temp. Sealed in dry,Room Temperature
pka 4.5(at 25℃)
Appearance White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H335-H302-H319-H315
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501

3-(2-nitrophenyl)propionic acid price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC N498113 3-(2-nitrophenyl)propanoicAcid 2001-32-3 250mg $330 2021-12-16 Buy
Matrix Scientific 165314 3-(2-Nitrophenyl)propanoic acid 2001-32-3 1g $530 2021-12-16 Buy
AK Scientific 0290AB 3-(2-Nitrophenyl)propanoicacid 2001-32-3 1g $238 2021-12-16 Buy
American Custom Chemicals Corporation CHM0109226 3-(2-NITROPHENYL)PROPANOIC ACID 95.00% 2001-32-3 1G $925.31 2021-12-16 Buy
American Custom Chemicals Corporation CHM0109226 3-(2-NITROPHENYL)PROPANOIC ACID 95.00% 2001-32-3 2.5G $1363.65 2021-12-16 Buy
Product number Packaging Price Buy
N498113 250mg $330 Buy
165314 1g $530 Buy
0290AB 1g $238 Buy
CHM0109226 1G $925.31 Buy
CHM0109226 2.5G $1363.65 Buy

3-(2-nitrophenyl)propionic acid Chemical Properties,Uses,Production

Synthesis

DIETHYL 2-(2-NITROBENZYL)MALONATE

59803-35-9

3-(2-nitrophenyl)propionic acid

2001-32-3

In a single-necked round-bottomed flask (2L), diethyl 2-(2-nitrobenzyl)malonate (8.7 g, 0.029 mol), 6N hydrochloric acid (131 mL) and acetic acid (131 mL) were added. The reaction mixture was heated and refluxed for 48 h, during which the reaction progress was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the reaction mixture was alkalized with 6 M sodium hydroxide solution (500 mL) and subsequently extracted with ethyl acetate (3 x 250 mL). The organic phases were combined, dried with anhydrous magnesium sulfate and concentrated under reduced pressure to remove the solvent. The crude product was purified by column chromatography (silica gel: 100-200 mesh, eluent: 40% hexane solution of ethyl acetate) to give 3-(2-nitrophenyl)propionic acid (5.4 g, 94% yield).

References

[1] Patent: WO2010/127855, 2010, A1. Location in patent: Page/Page column 145; 146
[2] Chemische Berichte, 1923, vol. 56, p. 2450
[3] Patent: WO2005/40119, 2005, A1. Location in patent: Page/Page column 48-49
[4] Patent: WO2005/40100, 2005, A1. Location in patent: Page/Page column 75-77

3-(2-nitrophenyl)propionic acid Preparation Products And Raw materials

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View Lastest Price from 3-(2-nitrophenyl)propionic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3-(2-nitrophenyl)propionic acid pictures 2020-01-09 3-(2-nitrophenyl)propionic acid
2001-32-3
US $6.68 / KG 1KG 97%-99% 1kg-1000kg Career Henan Chemical Co

3-(2-nitrophenyl)propionic acid Spectrum

Benzenepropanoic acid, 2-?nitro- 3-(2-Nitrophenyl)propionsure 3-(2-nitrophenyl)propionic acid 2-(2-Carboxyethyl)-1-nitrobenzene 2-Nitrobenzenepropanoic acid 3-(2-Nitrophenyl)propanoic acid 3-(2-Nitrophenyl) 2001-32-3