3-benzyloxy-cyclobutanecarboxylic acid
- CAS No.
- 4958-02-5
- Chemical Name:
- 3-benzyloxy-cyclobutanecarboxylic acid
- Synonyms
- 3-(benzyloxy)cyclobutane-1-carboxylic acid;3-benzyloxy-cyclobutanecarboxylic;3-benzyloxy-cyclobutanecarboxylic acid;3-Benzyloxycyclobutanecarboxylicacid,97%;3-(phenylmethoxy)cyclobutane-1-carboxylic acid;3-(phenylmethoxy)-1-cyclobutanecarboxylic acid;Cyclobutanecarboxylic acid, 3-(phenylmethoxy)-Cyclobutanecarboxylic acid, 3-(benzyloxy)-(6CI,7CI,8CI)
- CBNumber:
- CB5970906
- Molecular Formula:
- C12H14O3
- Molecular Weight:
- 206.24
- MDL Number:
- MFCD00512751
- MOL File:
- 4958-02-5.mol
- MSDS File:
- SDS
| Boiling point | 194 °C(Press: 6 Torr) |
|---|---|
| Density | 1.19 |
| storage temp. | Sealed in dry,Room Temperature |
| form | solid |
| pka | 4.48±0.40(Predicted) |
| Appearance | White to off-white Solid |
| InChI | 1S/C12H14O3/c13-12(14)10-6-11(7-10)15-8-9-4-2-1-3-5-9/h1-5,10-11H,6-8H2,(H,13,14) |
| InChIKey | YNNOFVDQHAHVFG-UHFFFAOYSA-N |
| SMILES | O=C(O)C(C1)CC1OCC2=CC=CC=C2 |
| UNSPSC Code | 12352106 |
| NACRES | NA.21 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36 | |||||||||
| Safety Statements | 26 | |||||||||
| WGK Germany | WGK 3 | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 2916200090 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Eye Irrit. 2 | |||||||||
| NFPA 704 |
|
3-benzyloxy-cyclobutanecarboxylic acid price More Price(50)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | MNO000198 | 3-Benzyloxycyclobutanecarboxylic acid | 4958-02-5 | 1g | $191 | 2026-04-30 | Buy |
| Apolloscientific | OR308099 | 3-(Benzyloxy)cyclobutanecarboxylic acid 97% | 4958-02-5 | 1g | $33 | 2026-06-04 | Buy |
| Apolloscientific | OR308099 | 3-(Benzyloxy)cyclobutanecarboxylic acid 97% | 4958-02-5 | 5g | $74 | 2026-06-04 | Buy |
| Apolloscientific | OR308099 | 3-(Benzyloxy)cyclobutanecarboxylic acid 97% | 4958-02-5 | 10g | $134 | 2026-06-04 | Buy |
| Apolloscientific | OR308099 | 3-(Benzyloxy)cyclobutanecarboxylic acid 97% | 4958-02-5 | 25g | $331 | 2026-06-04 | Buy |
3-benzyloxy-cyclobutanecarboxylic acid Chemical Properties, Uses, Production
Uses
3-Benzyloxycyclobutanecarboxylic acid is a useful building block for organic synthesis.
Synthesis
84182-46-7
4958-02-5
General procedure for the synthesis of 3-benzyloxy-cyclobutanecarboxylic acid from 3-benzyloxycyclobutane-1,1-dicarboxylic acid: 3-(benzyloxy)cyclobutane-1,1-dicarboxylic acid (1.5 g, 5.99 mmol) was dissolved in pyridine (3 mL) and the reaction was heated for 12 h at 120 °C in an oil bath. Upon completion of the reaction, the reaction mixture was cooled to room temperature and the pyridine was evaporated under reduced pressure. Subsequently, toluene (10 mL) was added to the residue and the resulting solution was washed with 1N hydrochloric acid solution (3 times), the organic phase was dried over anhydrous magnesium sulfate, filtered, and then concentrated under reduced pressure to give the brown oily target product 3-benzyloxy-cyclobutanecarboxylic acid (1.17 g, 95% yield).
References
[1] Patent: WO2011/143366, 2011, A1. Location in patent: Page/Page column 44
[2] Helvetica Chimica Acta, 1992, vol. 75, # 2, p. 589 - 603
[3] Collection of Czechoslovak Chemical Communications, 1982, vol. 47, # 9, p. 2440 - 2447
[4] Patent: WO2007/62332, 2007, A2. Location in patent: Page/Page column 17
[5] Patent: WO2007/62333, 2007, A2. Location in patent: Page/Page column 12
3-benzyloxy-cyclobutanecarboxylic acid Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| Tetranov Biopharm | 13526569071 | sales@leadmedpharm.com | China | 7881 | 64 |
| Shanghai Boc Chemical Co.,Ltd | 021-34975603-808 18721111801 | sales@bocpharma.com | China | 991 | 64 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| China Langchem Inc. | 0086-21-58956006 | China | 7798 | 57 | |
| Heterochem | 027-88041443 13072715837 | sales@hetero-chem.com | China | 695 | 58 |
| Supplier | Advantage |
|---|---|
| Alfa Aesar | 84 |
| Energy Chemical | 61 |
| Capot Chemical Co., Ltd | 66 |
| Beijing Ouhe Technology Co., Ltd | 60 |
| Tetranov Biopharm | 64 |
| Shanghai Boc Chemical Co.,Ltd | 64 |
| Nanjing Chemlin Chemical Co., Ltd | 64 |
| Shandong Xiya Chemical Co., Ltd | 57 |
| China Langchem Inc. | 57 |
| Heterochem | 58 |
View Latest Price from 3-benzyloxy-cyclobutanecarboxylic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-07-02 | 3-benzyloxy-cyclobutanecarboxylic acid
4958-02-5
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2020-02-26 | 3-(benzyloxy)cyclobutanecarboxylic acid
4958-02-5
|
10g | 99.0%+ | 100 tons | Shaanxi Dideu Medichem Co. Ltd |
-
- 3-benzyloxy-cyclobutanecarboxylic acid
4958-02-5
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 3-(benzyloxy)cyclobutanecarboxylic acid
4958-02-5
- 99.0%+
- Shaanxi Dideu Medichem Co. Ltd
