3-Hydroxy-cyclobutanecarboxylic acid ethyl ester
- CAS No.
- 17205-02-6
- Chemical Name:
- 3-Hydroxy-cyclobutanecarboxylic acid ethyl ester
- Synonyms
- ethyl 3-hydroxycyclobutane-1-carboxylate;Ethyl 3-hydroxycyclobutan...;Ethyl 3-hydroxycyclobutane-1-carboxylate 95%;3-Hydroxy-cyclobutanecarboxylic acid ethyl ester;Cyclobutanecarboxylic acid, 3-hydroxy-, ethyl ester
- CBNumber:
- CB61856435
- Molecular Formula:
- C7H12O3
- Molecular Weight:
- 144.17
- MDL Number:
- MFCD09758972
- MOL File:
- 17205-02-6.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| Ethyl 3-hydroxycyclobutane-1-carboxylate 95% | OR308100 | 1g | $41 |
| Ethyl 3-hydroxycyclobutane-1-carboxylate 95% | OR308100 | 5g | $102 |
| Ethyl 3-hydroxycyclobutane-1-carboxylate 95% | OR308100 | 25g | $476 |
| Ethyl 3-hydroxycyclobutanecarboxylate 95.0% | 2229-1-29 | 5g | $320 |
| Ethyl 3-hydroxycyclobutanecarboxylate 95.0% | 2229-1-29 | 25g | $850 |
| More product size | |||
| Boiling point | 209℃ |
|---|---|
| Density | 1.180 |
| refractive index | 1.4504 |
| Flash point | 83℃ |
| storage temp. | Inert atmosphere,Room Temperature |
| form | liquid |
| color | Clear Colourless |
| InChI | InChI=1S/C7H12O3/c1-2-10-7(9)5-3-6(8)4-5/h5-6,8H,2-4H2,1H3 |
| InChIKey | KTVUZBJHOAPDGC-UHFFFAOYSA-N |
| SMILES | C1(C(OCC)=O)CC(O)C1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H336 |
| Precautionary statements | P501-P261-P271-P304+P340+P312-P403+P233-P405 |
| HS Code | 2918300090 |
3-Hydroxy-cyclobutanecarboxylic acid ethyl ester price More Price(38)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR308100 | Ethyl 3-hydroxycyclobutane-1-carboxylate 95% | 17205-02-6 | 1g | $41 | 2026-06-04 | Buy |
| Apolloscientific | OR308100 | Ethyl 3-hydroxycyclobutane-1-carboxylate 95% | 17205-02-6 | 5g | $102 | 2026-06-04 | Buy |
| Apolloscientific | OR308100 | Ethyl 3-hydroxycyclobutane-1-carboxylate 95% | 17205-02-6 | 25g | $476 | 2026-06-04 | Buy |
| SynQuest Laboratories | 2229-1-29 | Ethyl 3-hydroxycyclobutanecarboxylate 95.0% | 17205-02-6 | 5g | $320 | 2026-05-22 | Buy |
| SynQuest Laboratories | 2229-1-29 | Ethyl 3-hydroxycyclobutanecarboxylate 95.0% | 17205-02-6 | 25g | $850 | 2026-05-22 | Buy |
3-Hydroxy-cyclobutanecarboxylic acid ethyl ester Chemical Properties,Uses,Production
Synthesis
87121-89-9
17205-02-6
General procedure for the synthesis of ethyl 3-hydroxycyclobutanecarboxylate from ethyl 3-oxocyclobutanecarboxylate: to a solution of ethyl 3-oxocyclobutanecarboxylate (0.18 g, 1.27 mmol) in methanol (10 mL) was slowly added sodium borohydride (0.048 g, 1.27 mmol) at 0 °C. The reaction mixture was stirred continuously at 0 °C for 30 min, followed by quenching the reaction with aqueous 1N hydrochloric acid. Volatile solvents were removed by distillation under reduced pressure and the residue was extracted by partitioning with ethyl acetate and 1N aqueous hydrochloric acid. The organic phase was dried over anhydrous magnesium sulfate and concentrated under reduced pressure to afford the target product ethyl 3-hydroxycyclobutanecarboxylate (0.17 g, 93% yield) as a mixture of cis and trans isomers. The product was characterized by 1H NMR (500 MHz, CDCl3), δ 4.17-4.24 (m, 1H), 4.15 (d, J=7.2 Hz, 2H), 2.54-2.66 (m, 3H), 2.11-2.22 (m, 2H), 1.27 (t, J=7.2 Hz, 3H).
References
[1] Patent: WO2016/40223, 2016, A1. Location in patent: Paragraph 00218
[2] Patent: WO2018/162607, 2018, A1. Location in patent: Paragraph 0769; 0770
[3] Patent: WO2016/24185, 2016, A1. Location in patent: Page/Page column 127
[4] Patent: US5681858, 1997, A
[5] Patent: WO2011/106273, 2011, A1. Location in patent: Page/Page column 72
3-Hydroxy-cyclobutanecarboxylic acid ethyl ester Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20111 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10399 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8491 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63645 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10817 | 58 |
| career henan chemical co | +86-0371-86658258 | factory@coreychem.com | China | 29780 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21135 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 | sales@tnjchem.com | China | 34526 | 58 |
| Finetech Industry Limited | +86-27-8746-5837 +86-18627785180 | info@finetechnology-ind.com | China | 9539 | 58 |
View Lastest Price from 3-Hydroxy-cyclobutanecarboxylic acid ethyl ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-17 | Ethyl 3-hydroxycyclobutanecarboxylate
17205-02-6
|
$1.00-200.00 | 1KG | 99%, 99.5% Sublimated | Henan Fengda Chemical Co., Ltd | ||
 |
2019-12-27 | 3-Hydroxy-cyclobutanecarboxylic acid ethyl ester
17205-02-6
|
$1.00 | 1KG | 99% | 200kg | Career Henan Chemical Co |
-
- Ethyl 3-hydroxycyclobutanecarboxylate
17205-02-6
- $1.00-200.00
- 99%, 99.5% Sublimated
- Henan Fengda Chemical Co., Ltd
-
- 3-Hydroxy-cyclobutanecarboxylic acid ethyl ester
17205-02-6
- $1.00
- 99%
- Career Henan Chemical Co
