Mephetyl tetrazole
- CAS No.
- 916923-10-9
- Chemical Name:
- Mephetyl tetrazole
- Synonyms
- Mephetyl tetrazole;1-[2-(4-Methoxyphenyl)ethyl]-5-(1-p-tolylcyclopropyl)-1H-tetrazole;1H-Tetrazole, 1-[2-(4-methoxyphenyl)ethyl]-5-[1-(4-methylphenyl)cyclopropyl]-
- CBNumber:
- CB5972940
- Molecular Formula:
- C20H22N4O
- Molecular Weight:
- 334.41
- MDL Number:
- MFCD11045297
- MOL File:
- 916923-10-9.mol
- TDS File:
- TDS
| Boiling point | 558.4±39.0 °C(Predicted) |
|---|---|
| Density | 1.21±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO: >5mg/mL |
| pka | 1.11±0.10(Predicted) |
| form | oil |
| color | pale yellow |
| InChI | 1S/C20H22N4O/c1-15-3-7-17(8-4-15)20(12-13-20)19-21-22-23-24(19)14-11-16-5-9-18(25-2)10-6-16/h3-10H,11-14H2,1-2H3 |
| InChIKey | VREPWWBWXVLSEF-UHFFFAOYSA-N |
| SMILES | COc1ccc(CCn2nnnc2C3(CC3)c4ccc(C)cc4)cc1 |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| PPE | Eyeshields, Gloves, type N95 (US) |
|---|---|
| Safety Statements | 22-24/25 |
| WGK Germany | 3 |
| Storage Class | 11 - Combustible Solids |
Mephetyl tetrazole price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | M7945 | Mephetyl tetrazole ≥98% (HPLC), oil | 916923-10-9 | 5mg | $219 | 2026-04-30 | Buy |
| Sigma-Aldrich | M7945 | Mephetyl tetrazole ≥98% (HPLC), oil | 916923-10-9 | 25mg | $923 | 2023-01-07 | Buy |
| American Custom Chemicals Corporation | CBL0000326 | MEPHETYL TETRAZOLE 95.00% | 916923-10-9 | 5MG | $743.88 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CBL0000326 | MEPHETYL TETRAZOLE 95.00% | 916923-10-9 | 25MG | $1203.05 | 2021-12-16 | Buy |
Mephetyl tetrazole Chemical Properties,Uses,Production
Uses
Mephetyl tetrazole is a potassium channel Kv1.5 blocker, with an IC50 of 330 nM. Mephetyl tetrazole can be used for the research of cancer[1].
Biological Activity
Mephetyl tetrazole is a potent and selective Kv1.5 potassium channel blocker. IC50 = 330 nM; shows selective atrial prolongation (40%) of effective refractory period (ERP), but no effect on ventricular ERP Kv1.5 channel is a molecular target for the treatment of atrial fibrillation.
References
[1] Felipe A, et al. Targeting the voltage-dependent K(+) channels Kv1.3 and Kv1.5 as tumor biomarkers for cancer detection and prevention. Curr Med Chem. 2012;19(5):661-74. DOI:10.2174/092986712798992048
Mephetyl tetrazole Preparation Products And Raw materials
Raw materials
Preparation Products
Mephetyl tetrazole Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol | 400-821-0310 15002144251 | xuexiang.shao@tsbiochem.com | China | 29128 | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | +86-88938639 +86-17705817739 | info@dycnchem.com | China | 53799 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol | 58 |
| DAYANG CHEM (HANGZHOU) CO.,LTD | 58 |
