ChemicalBook >> CAS DataBase List >>4-Piperidinone, 1-[[1-[(2-fluorophenyl)methyl]-1H-1,2,3-triazol-4-yl]methyl]-3,5-bis[(4-methylphenyl)methylene]-, (3E,5E)-

4-Piperidinone, 1-[[1-[(2-fluorophenyl)methyl]-1H-1,2,3-triazol-4-yl]methyl]-3,5-bis[(4-methylphenyl)methylene]-, (3E,5E)-

4-Piperidinone, 1-[[1-[(2-fluorophenyl)methyl]-1H-1,2,3-triazol-4-yl]methyl]-3,5-bis[(4-methylphenyl)methylene]-, (3E,5E)- structure

CAS No.: 1983924-20-4

Chemical Name:: 4-Piperidinone, 1-[[1-[(2-fluorophenyl)methyl]-1H-1,2,3-triazol-4-yl]methyl]-3,5-bis[(4-methylphenyl)methylene]-, (3E,5E)-

Synonyms: MDK4204;MDK-4204;MDK 4204;Anticancer AgentI;Anticancer Agent-I;Anticancer Agent I;4-Piperidinone, 1-[[1-[(2-fluorophenyl)methyl]-1H-1,2,3-triazol-4-yl]methyl]-3,5-bis[(4-methylphenyl)methylene]-, (3E,5E)-

CBNumber:: CB59925299

Molecular Formula:: C31H29FN4O

Molecular Weight:: 492.59

MDL Number:

MOL File:: 1983924-20-4.mol

MSDS File:: SDS

Last updated:2026-05-11 15:21:01

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4-Piperidinone, 1-[[1-[(2-fluorophenyl)methyl]-1H-1,2,3-triazol-4-yl]methyl]-3,5-bis[(4-methylphenyl)methylene]-, (3E,5E)- Properties

Boiling point	702.5±70.0 °C(Predicted)
Density	1.17±0.1 g/cm3(Predicted)
pka	2.91±0.20(Predicted)

4-Piperidinone, 1-[[1-[(2-fluorophenyl)methyl]-1H-1,2,3-triazol-4-yl]methyl]-3,5-bis[(4-methylphenyl)methylene]-, (3E,5E)- Chemical Properties, Uses, Production

Uses

Anticancer agent 255 is a monocarbonylated curcumin-1,2,3-oxazole conjugate with significant anticancer activity. The IC50 values of Anticancer agent 255 in prostate cancer cells PC-3 and DU-145 are 8.8μM and 9.5μM respectively. The IC50 values of Anticancer agent 255 against breast cancer cells MCF-7, MDA-MB-231 and 4T1 are 6μM, 10μM and 6.4μM, showing good anti-cancer activity Effect. Anticancer agent 255 can induce mitochondria-mediated apoptosis in cancer cells and prevent cell cycle progression. Anticancer agent 255 down-regulated the cell proliferation marker PCNA and inhibited the activation of cell survival proteins. Anticancer agent 255 up-regulated the pro-apoptotic protein Bax and down-regulated the anti-apoptotic protein Bcl-2[1].

References

[1] Synthesis and biological evaluation of some novel triazole hybrids of curcumin mimics and their selective anticancer activity against breast and prostate cancer cell lines

4-Piperidinone, 1-[[1-[(2-fluorophenyl)methyl]-1H-1,2,3-triazol-4-yl]methyl]-3,5-bis[(4-methylphenyl)methylene]-, (3E,5E)- Preparation Products And Raw materials

Raw materials

Preparation Products

4-Piperidinone, 1-[[1-[(2-fluorophenyl)methyl]-1H-1,2,3-triazol-4-yl]methyl]-3,5-bis[(4-methylphenyl)methylene]-, (3E,5E)- Suppliers

Global Suppliers ( 3)

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	marketing@targetmol.com	United States	32431	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58
TargetMol Chemicals Inc.	13564774135	marketing@targetmol.com	United States	19950	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
TargetMol Chemicals Inc.	58
TargetMol Chemicals Inc.	58

View Latest Price from 4-Piperidinone, 1-[[1-[(2-fluorophenyl)methyl]-1H-1,2,3-triazol-4-yl]methyl]-3,5-bis[(4-methylphenyl)methylene]-, (3E,5E)- manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-05-11	MDK-4204 1983924-20-4	$1520.00-2500.00			10g	TargetMol Chemicals Inc.

MDK-4204
1983924-20-4
$1520.00-2500.00
TargetMol Chemicals Inc.

1983924-20-4 (4-Piperidinone, 1-[[1-[(2-fluorophenyl)methyl]-1H-1,2,3-triazol-4-yl]methyl]-3,5-bis[(4-methylphenyl)methylene]-, (3E,5E)-) Related Search:

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4-Piperidinone, 1-[[1-[(2-fluorophenyl)methyl]-1H-1,2,3-triazol-4-yl]methyl]-3,5-bis[(4-methylphenyl)methylene]-, (3E,5E)- Anticancer Agent I Anticancer AgentI Anticancer Agent-I MDK 4204 MDK4204 MDK-4204 1983924-20-4 C31H29FN4O