ChemicalBook >> CAS DataBase List >>trans-4-Cyclohexyl-L-proline
trans-4-Cyclohexyl-L-proline
- CAS No.
- 103201-78-1
- Chemical Name:
- trans-4-Cyclohexyl-L-proline
- Synonyms
- (2S,4S)-4-cyclohexylpyrrolidine-2-carboxylic acid;H-Chpro-OH;Estreptoquinasa;Fosinopril Intermediate 2;rans-4-Cyclohexyl-L-proline;H-trans-4-Cyclohexyl-Pro-OH;(4S)- 4-cyclohexyl-L-Proline;trans-4-Cyclohexyl-L-proline;L-Proline, 4-cyclohexyl-, (4S)-;12. trans-4-cyclohexyl-L-proline
- CBNumber:
- CB6119072
- Molecular Formula:
- C11H19NO2
- Molecular Weight:
- 197.27
- MDL Number:
- MFCD08063935
- MOL File:
- 103201-78-1.mol
- MSDS File:
- SDS
Last updated:2026-05-28 01:30:01
| Melting point | 260-262 °C(Solv: methanol (67-56-1); ethyl ether (60-29-7)) |
|---|---|
| Boiling point | 343.9±35.0 °C(Predicted) |
| Density | 1.113±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| pka | 2.35±0.40(Predicted) |
| Appearance | White to off-white Solid |
| optical activity | -30.2°(C=0.011192 g/mL ACOH) |
| InChI | InChI=1S/C11H19NO2/c13-11(14)10-6-9(7-12-10)8-4-2-1-3-5-8/h8-10,12H,1-7H2,(H,13,14)/t9-,10+/m1/s1 |
| InChIKey | XRZWVSXEDRYQGC-ZJUUUORDSA-N |
| SMILES | C(O)(=O)[C@@H]1C[C@@H](C2CCCCC2)CN1 |
| CAS DataBase Reference | 103201-78-1(CAS DataBase Reference) |
trans-4-Cyclohexyl-L-proline price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | DEA20178 | trans-4-Cyclohexyl-L-proline | 103201-78-1 | 25g | $454.25 | 2026-06-04 | Buy |
| Biosynth | DEA20178 | trans-4-Cyclohexyl-L-proline | 103201-78-1 | 50g | $714 | 2026-06-04 | Buy |
| Biosynth | DEA20178 | trans-4-Cyclohexyl-L-proline | 103201-78-1 | 100g | $909 | 2026-06-04 | Buy |
| Biosynth | DEA20178 | trans-4-Cyclohexyl-L-proline | 103201-78-1 | 250g | $1622.5 | 2026-06-04 | Buy |
| Synthonix | C61513 | (2S,4S)-4-Cyclohexylpyrrolidine-2-carboxylic acid >98% | 103201-78-1 | 1g | $21 | 2026-05-06 | Buy |
trans-4-Cyclohexyl-L-proline Chemical Properties,Uses,Production
Synthesis
96314-26-0
103201-78-1
The general procedure for the synthesis of (2S,4S)-4-cyclohexylpyrrolidine-2-carboxylic acid from (2S,4S)-4-phenylpyrrolidine-2-carboxylic acid was as follows: compound V (1.2 g), 5% rhodium-carbon catalyst (0.24 g), concentrated hydrochloric acid (1.2 ml), and methanol (12 ml) were added to the reaction flask sequentially. The reaction mixture was stirred and hydrogenated at 30 °C under 2.0 MPa hydrogen pressure. After 2 hours of reaction, the reaction mixture was filtered under reduced pressure. The filtrate was concentrated under reduced pressure to give a white solid product (1.11 g) in 90.0% yield.
References
[1] Patent: CN107365268, 2017, A. Location in patent: Paragraph 0016
trans-4-Cyclohexyl-L-proline Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 142)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai ACT chemical Limited | 021-59904146 18001826933 | sales@actchemical.com | China | 476 | 56 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
| XiaoGan ShenYuan ChemPharm co,ltd | 15527621225; 15527621225 | 1791901229@qq.com | China | 6746 | 52 |
| China Langchem Inc. | 0086-21-58956006 | China | 7798 | 57 | |
| Tianjin heowns Biochemical Technology Co., Ltd. | 400 638 7771 | sales@heowns.com | China | 14412 | 57 |
| Sci General Material & Chemical Ltd | 021-58388037;21-58388037 13472507714 | 35177634@qq.com;1589045147@qq.com | China | 795 | 55 |
| Shanghai Topbiochem Technology Co., Ltd | +86-21-60341587 | sales@topbiochem.com | China | 6166 | 58 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 400-6206333 13167063860 | anhua.mao@aladdin-e.com | China | 29985 | 65 |
View Lastest Price from trans-4-Cyclohexyl-L-proline manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | trans-4-Cyclohexyl-L-proline
103201-78-1
|
$7.00 | 1KG | 99% | 100kg | Career Henan Chemical Co |
-
- trans-4-Cyclohexyl-L-proline
103201-78-1
- $7.00
- 99%
- Career Henan Chemical Co
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(Trans)-4-CyclohexylprolineQ: What is
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(Trans)-4-Cyclohexylproline
Estreptoquinasa
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(2S,4S)-4-cyclohexylpyrrolidine-2-carboxylic acid
12. trans-4-cyclohexyl-L-proline
103201-78-1
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C11H13NO2
