4-Chloroformylphthalic anhydride
- CAS No.
- 1204-28-0
- Chemical Name:
- 4-Chloroformylphthalic anhydride
- Synonyms
- TMAC;TRIMELLITIC ANHYDRIDE CHLORIDE;1,3-dioxo-1,3-dihydroisobenzofuran-5-carbonyl chloride;trimellitic;TRIMELLITIC ANHYDRIDE ACID CHLORIDE;1,3-Dioxo-1,3-dihydro-2-benzofuran-5-carbonyl chloride;TrimeL;SKL1280;AKOS BBS-00003912;itic anhydride chL
- CBNumber:
- CB6124898
- Molecular Formula:
- C9H3ClO4
- Molecular Weight:
- 210.57
- MDL Number:
- MFCD00005924
- MOL File:
- 1204-28-0.mol
- MSDS File:
- SDS
| Melting point | 66-68 °C(lit.) |
|---|---|
| Boiling point | 302.37°C (rough estimate) |
| Density | 1.5015 (rough estimate) |
| vapor pressure | 0.017Pa at 20℃ |
| refractive index | 1.4571 (estimate) |
| storage temp. | 2-8°C |
| solubility | soluble in Chloroform |
| form | powder to lump |
| color | White to Almost white |
| Water Solubility | decomposes |
| Sensitive | Moisture Sensitive |
| BRN | 610823 |
| InChI | 1S/C9H3ClO4/c10-7(11)4-1-2-5-6(3-4)9(13)14-8(5)12/h1-3H |
| InChIKey | NJMOHBDCGXJLNJ-UHFFFAOYSA-N |
| SMILES | ClC(=O)c1ccc2C(=O)OC(=O)c2c1 |
| Indirect Additives used in Food Contact Substances | BENZOYL CHLORIDE-3,4-DICARBOXYLIC ANHYDRIDE |
| FDA 21 CFR | 177.2450 |
| CAS DataBase Reference | 1204-28-0(CAS DataBase Reference) |
| FDA UNII | 56231EU26X |
| NIST Chemistry Reference | Phthalic , 4-(chloroformyl)-,anhydride(1204-28-0) |
| EPA Substance Registry System | 5-Isobenzofurancarbonyl chloride, 1,3-dihydro-1,3-dioxo- (1204-28-0) |
| UNSPSC Code | 12162002 |
| NACRES | NA.23 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H314 | |||||||||
| Precautionary statements | P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363 | |||||||||
| PPE | Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges | |||||||||
| Hazard Codes | C | |||||||||
| Risk Statements | 34-29 | |||||||||
| Safety Statements | 26-36/37/39-45 | |||||||||
| RIDADR | UN 3261 8/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10-21 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29173990 | |||||||||
| Storage Class | 8A - Combustible corrosive hazardous materials | |||||||||
| Hazard Classifications | Eye Dam. 1 Skin Corr. 1B |
|||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
4-Chloroformylphthalic anhydride price More Price(41)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | T68020 | Trimellitic anhydride chloride 98% | 1204-28-0 | 100g | $52.3 | 2023-06-20 | Buy |
| Sigma-Aldrich | T68020 | Trimellitic anhydride chloride 98% | 1204-28-0 | 500g | $272 | 2023-06-20 | Buy |
| TCI Chemical | T1079 | Trimellitic Anhydride Chloride >98.0%(T) | 1204-28-0 | 25g | $32 | 2026-04-30 | Buy |
| TCI Chemical | T1079 | Trimellitic Anhydride Chloride >98.0%(T) | 1204-28-0 | 100g | $74 | 2026-04-30 | Buy |
| Apolloscientific | OR63040 | 1,3-Dihydro-1,3-dioxobenzo[c]furan-5-carbonyl chloride 99% | 1204-28-0 | 5g | $21 | 2026-06-04 | Buy |
4-Chloroformylphthalic anhydride Chemical Properties, Uses, Production
Chemical Properties
white crystalline solid
Uses
Trimellitic Anhydride Chloride can be used as a reagent to synthesize optical polyamideimides.
Synthesis Reference(s)
The Journal of Organic Chemistry, 38, p. 2557, 1973 DOI: 10.1021/jo00954a034
Flammability and Explosibility
Not classified
Synthesis
552-30-7
1204-28-0
The general procedure for the synthesis of 1,3-dioxo-1,3-dihydroisobenzofuran-5-carbonyl chloride from trimellitic anhydride was as follows: trimellitic anhydride (50 g) and cyclohexane (45 mL) were added to a reaction flask containing 4-dimethylaminopyridine (0.05 g), and heated to 90 °C. Subsequently, thionyl chloride (37.2 g, molar ratio of trimellitic anhydride to thionyl chloride 1:1.2) was added slowly and the reaction mixture was refluxed for 6 hours. Upon completion of the reaction, it was confirmed that no gas was produced. At the end of the reaction, the remaining cyclohexane and excess thionyl chloride were removed by distillation at 90 °C and the solution was recovered at -0.085 MPa. Next, the 180-190 °C fraction was collected by vacuum distillation (vacuum of 750 mmHg) to give trimellitic anhydride chloride (47.6 g). After cooling, the product was a white solid with a melting point of 67.5~68.8 °C, and the HPLC purity was 99.5% in 86.9% yield.
References
[1] Patent: CN103626729, 2016, B. Location in patent: Paragraph 0026; 0027
[2] Patent: CN106748963, 2017, A. Location in patent: Paragraph 0048; 0049; 0050; 0051
[3] Patent: CN108341796, 2018, A. Location in patent: Paragraph 0016; 0017; 0018; 0019; 0020; 0021
[4] Patent: US10093929, 2018, B2. Location in patent: Page/Page column 2-3
4-Chloroformylphthalic anhydride Preparation Products And Raw materials
Raw materials
Preparation Products
1of2
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan yuqing jiaheng pharmaceutical co. LTD | 027-83855381 15827508403 | xiaozhan0503@163.com | China | 978 | 58 |
| Hubei Xicheng New Materials Co., Ltd. | 13419687235 13419687235 | 3833072903@qq.com | China | 68 | 58 |
| Kandis Chemical (Hubei) Co., Ltd | 13343438265 | 1164531526@qq.com | China | 2929 | 58 |
| Changzhou Xuanming Pharmaceutical Technology Co., Ltd. | 15995069468 15995069468 | 3398435160@qq.com | China | 300 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Chemsky（shanghai）International Co.,Ltd. | 021-50135380 | shchemsky@sina.com | China | 32273 | 50 |
Related articles
- Application Research of 4-Chloroformylphthalic anhydride
- Trimellitic anhydride chloride is a highly reactive aromatic carboxylic acid derivative and a pivotal industrial chemical inte....
- Apr 19,2026
View Latest Price from 4-Chloroformylphthalic anhydride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-06-20 | Trimellitic Anhydride Chloride
1204-28-0
|
1kg | 0.99 | 1000kg | Hebei Yanxi Chemical Co., Ltd. | ||
 |
2023-07-31 | 4-Chloroformylphthalic anhydride
1204-28-0
|
$1.00 | 20kg | 99% | 500tons | Hebei Linwo New Material Technology Co., LTD | |
 |
2023-03-27 | 4-Chloroformylphthalic anhydride
1204-28-0
|
$25.00 | 1KG | 0.99 | 50000KG/MONTH | XINGTAI XINGJIU NEW MATERIAL TECHNOLOGY CO., LTD |
-
- Trimellitic Anhydride Chloride
1204-28-0
- $0.00
- 0.99
- Hebei Yanxi Chemical Co., Ltd.
-
- 4-Chloroformylphthalic anhydride
1204-28-0
- $1.00
- 99%
- Hebei Linwo New Material Technology Co., LTD
-
- 4-Chloroformylphthalic anhydride
1204-28-0
- $25.00
- 0.99
- XINGTAI XINGJIU NEW MATERIAL TECHNOLOGY CO., LTD
1204-28-0 (4-Chloroformylphthalic anhydride) Related Search:
1of4
