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ChemicalBook >> CAS DataBase List >>1H-Pyrazole-3-carboxamide, N-[5-[(6,7-dimethoxy-4-quinolinyl)oxy]-2-pyridinyl]-1-ethyl-5-methyl-4-(2,2,2-trifluoroethoxy)-

1H-Pyrazole-3-carboxamide, N-[5-[(6,7-dimethoxy-4-quinolinyl)oxy]-2-pyridinyl]-1-ethyl-5-methyl-4-(2,2,2-trifluoroethoxy)-

1H-Pyrazole-3-carboxamide, N-[5-[(6,7-dimethoxy-4-quinolinyl)oxy]-2-pyridinyl]-1-ethyl-5-methyl-4-(2,2,2-trifluoroethoxy)- Structure
1H-Pyrazole-3-carboxamide, N-[5-[(6,7-dimethoxy-4-quinolinyl)oxy]-2-pyridinyl]-1-ethyl-5-methyl-4-(2,2,2-trifluoroethoxy)- structure
CAS No.
2394874-60-1
Chemical Name:
1H-Pyrazole-3-carboxamide, N-[5-[(6,7-dimethoxy-4-quinolinyl)oxy]-2-pyridinyl]-1-ethyl-5-methyl-4-(2,2,2-trifluoroethoxy)-
Synonyms
Axl/Mer/CSF1R-IN-1;1H-Pyrazole-3-carboxamide, N-[5-[(6,7-dimethoxy-4-quinolinyl)oxy]-2-pyridinyl]-1-ethyl-5-methyl-4-(2,2,2-trifluoroethoxy)-
CBNumber:
CB613143606
Molecular Formula:
C25H24F3N5O5
Molecular Weight:
531.48
MDL Number:
MOL File:
2394874-60-1.mol
MSDS File:
SDS
Last updated:2026-07-27 17:00:41
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1H-Pyrazole-3-carboxamide, N-[5-[(6,7-dimethoxy-4-quinolinyl)oxy]-2-pyridinyl]-1-ethyl-5-methyl-4-(2,2,2-trifluoroethoxy)- Properties

Boiling point 602.8±55.0 °C(Predicted)
Density 1.38±0.1 g/cm3(Predicted)
pka 10.57±0.70(Predicted)

1H-Pyrazole-3-carboxamide, N-[5-[(6,7-dimethoxy-4-quinolinyl)oxy]-2-pyridinyl]-1-ethyl-5-methyl-4-(2,2,2-trifluoroethoxy)- Chemical Properties, Uses, Production

Uses

Axl/Mer-IN-1 (Compound 1) is an Axl/Mer receptor tyrosine kinase (Axl/Mer RTK) and CSF1R inhibitor with Kds of <0.1 μM[1].

IC 50

Axl; Mer

References

[1] Kiyean NAM, et al. Quinoline derivatives as inhibitors of axl/mer rtk and csf1r. Patent WO2019229251A1.

1H-Pyrazole-3-carboxamide, N-[5-[(6,7-dimethoxy-4-quinolinyl)oxy]-2-pyridinyl]-1-ethyl-5-methyl-4-(2,2,2-trifluoroethoxy)- Preparation Products And Raw materials

Raw materials

Preparation Products

1H-Pyrazole-3-carboxamide, N-[5-[(6,7-dimethoxy-4-quinolinyl)oxy]-2-pyridinyl]-1-ethyl-5-methyl-4-(2,2,2-trifluoroethoxy)- Suppliers

Global Suppliers ( 2)
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58
Supplier Advantage
TargetMol Chemicals Inc. 58
TargetMol Chemicals Inc. 58

View Latest Price from 1H-Pyrazole-3-carboxamide, N-[5-[(6,7-dimethoxy-4-quinolinyl)oxy]-2-pyridinyl]-1-ethyl-5-methyl-4-(2,2,2-trifluoroethoxy)- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Axl/Mer/CSF1R-IN-1 pictures 2026-07-27 Axl/Mer/CSF1R-IN-1
2394874-60-1
 $2120.00-3700.00 10g TargetMol Chemicals Inc.

2394874-60-1 (1H-Pyrazole-3-carboxamide, N-[5-[(6,7-dimethoxy-4-quinolinyl)oxy]-2-pyridinyl]-1-ethyl-5-methyl-4-(2,2,2-trifluoroethoxy)-) Related Search:

AXL Protein, HUMAN (BIOTINYLATED, HEK293, HIS-AVI) AXL Protein, HUMAN (HEK293, FC) CSF1R Protein, HUMAN (HEK293, HIS-FC) CSF1R Protein, MOUSE (HEK293, FC) Mer Protein, Cynomolgus (HEK293, Fc)
PF 477736

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1H-Pyrazole-3-carboxamide, N-[5-[(6,7-dimethoxy-4-quinolinyl)oxy]-2-pyridinyl]-1-ethyl-5-methyl-4-(2,2,2-trifluoroethoxy)- Axl/Mer/CSF1R-IN-1 2394874-60-1