ChemicalBook >> CAS DataBase List >>3-Pyridinecarboxamide, N-[4-(3,5-dimethylphenyl)-5-(4-pyridinyl)-2-thiazolyl]-, hydrochloride (1:2)

3-Pyridinecarboxamide, N-[4-(3,5-dimethylphenyl)-5-(4-pyridinyl)-2-thiazolyl]-, hydrochloride (1:2)

CAS No.
325767-87-1
Chemical Name:
3-Pyridinecarboxamide, N-[4-(3,5-dimethylphenyl)-5-(4-pyridinyl)-2-thiazolyl]-, hydrochloride (1:2)
Synonyms
DPTN 2HCL;DPTN dihydrochloride;N-(4-(3,5-Dimethylphenyl)-5-(pyridin-4-yl)thiazol-2-yl)nicotinamide dihydrochloride;3-Pyridinecarboxamide, N-[4-(3,5-dimethylphenyl)-5-(4-pyridinyl)-2-thiazolyl]-, hydrochloride (1:2)
CBNumber:
CB613339456
Molecular Formula:
C22H18N4OS.2ClH
Molecular Weight:
459.39
MDL Number:
MOL File:
325767-87-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-16 07:06:08

3-Pyridinecarboxamide, N-[4-(3,5-dimethylphenyl)-5-(4-pyridinyl)-2-thiazolyl]-, hydrochloride (1:2) Properties

solubility Soluble to 20 mM in DMSO with gentle warming
form Solid
color Light yellow to yellow

3-Pyridinecarboxamide, N-[4-(3,5-dimethylphenyl)-5-(4-pyridinyl)-2-thiazolyl]-, hydrochloride (1:2) price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 41540 DPTN (hydrochloride) ≥98% 325767-87-1 5mg $98 2026-04-30 Buy
Cayman Chemical 41540 DPTN (hydrochloride) ≥98% 325767-87-1 10mg $186 2026-04-30 Buy
Cayman Chemical 41540 DPTN (hydrochloride) ≥98% 325767-87-1 25mg $416 2026-04-30 Buy
Cayman Chemical 41540 DPTN (hydrochloride) ≥98% 325767-87-1 50mg $735 2026-04-30 Buy
ChemScene CS-0652599 DPTN dihydrochloride 98.47% 325767-87-1 5mg $135 2026-06-04 Buy
Product number Packaging Price Buy
41540 5mg $98 Buy
41540 10mg $186 Buy
41540 25mg $416 Buy
41540 50mg $735 Buy
CS-0652599 5mg $135 Buy

3-Pyridinecarboxamide, N-[4-(3,5-dimethylphenyl)-5-(4-pyridinyl)-2-thiazolyl]-, hydrochloride (1:2) Chemical Properties,Uses,Production

Uses

DPTN is a potent and selective human, mouse, and rat A3AR antagonist with Ki values of 1.65, 9.61, and 8.53nM, respectively[1].

Biological Activity

DPTN is a potent and selective A3 adenosine receptor antagonist (Ki values are in the range 0.36 - 1.65 nM (hA3AR) and 1.6 - 8.53 nM (rA3AR)). Reduces intrapulmonary pressure when combined with Dexamethasone .

IC 50

hA3: 1.65 nM (Ki)

storage

Store at -20°C

References

[1] Zhan-Guo Gao, et al. Pharmacological characterization of DPTN and other selective A3 adenosine receptor antagonist. Purinergic Signal. 2021 Dec;17(4):737-746. DOI:10.1007/s11302-021-09823-5

3-Pyridinecarboxamide, N-[4-(3,5-dimethylphenyl)-5-(4-pyridinyl)-2-thiazolyl]-, hydrochloride (1:2) Preparation Products And Raw materials

Raw materials

Preparation Products

3-Pyridinecarboxamide, N-[4-(3,5-dimethylphenyl)-5-(4-pyridinyl)-2-thiazolyl]-, hydrochloride (1:2) Suppliers

Global( 17)Suppliers
Supplier Tel Email Country ProdList Advantage
Nanjing Chemlin Chemical Co., Ltd 025-83697070 13770331960 info@chemlin.com.cn China 16305 64
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Shanghai Chaolan Chemical Technology Center QQ:65489617 13301690235 Sales@ATKchemical.com China 9699 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Wuxi Donghe Pharmaceutical Technology Co., Ltd. 63313187 15358055255 63313187@qq.com China 1982 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 psaitong@jm-bio.com China 27626 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 59929 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
Hubei wei shi reagent group ltd., company 17771898297 13125137661 2853877621@qq.com China 7993 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58

View Lastest Price from 3-Pyridinecarboxamide, N-[4-(3,5-dimethylphenyl)-5-(4-pyridinyl)-2-thiazolyl]-, hydrochloride (1:2) manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
DPTN dihydrochloride pictures 2026-07-15 DPTN dihydrochloride
325767-87-1
$43.00-168.00 99.95% 10g TargetMol Chemicals Inc.

3-Pyridinecarboxamide, N-[4-(3,5-dimethylphenyl)-5-(4-pyridinyl)-2-thiazolyl]-, hydrochloride (1:2) Spectrum

3-Pyridinecarboxamide, N-[4-(3,5-dimethylphenyl)-5-(4-pyridinyl)-2-thiazolyl]-, hydrochloride (1:2) DPTN dihydrochloride N-(4-(3,5-Dimethylphenyl)-5-(pyridin-4-yl)thiazol-2-yl)nicotinamide dihydrochloride DPTN 2HCL 325767-87-1 C22H18N4OS2ClH