NF 279
- CAS No.
- 202983-32-2
- Chemical Name:
- NF 279
- Synonyms
- NF 279;CS-319;NF279 - CAS 202983-32-2 - Calbiochem;8,8[Carbonylbis(imino-4,1-phenylenecarbonylimino-4,1-phenylenecarbonylimino)]bis-1,3,5-naphthalenetrisulfonicacidhex;8,8'-[Carbonylbis(imino-4,1-phenylenecarbonylimino-4,1-phenylenecarbonylimino)]bis-1,3,5-naphthalenetrisulfonic acid;8,81/2-[Carbonylbis-(imino-4,1-phenylenecarbonylimino-4,1-phenylenecarbonylimino)]bis-1,3,5-naphthalenetrisulfonic acid;8,8'-(CARBONYLBIS(IMINO-4,1-PHENYLENECARBONYLIMINO-4,1-PHENYLENECARBONYLIMINO))BIS-1,3,5-NAPHTHALENETRISULFONIC ACID, NA;8,8'-[Carbonylbis(imino-4,1-phenylenecarbonylimino-4,1-phenylenecarbonylimino)]bis-1,3,5-naphthalenetrisulfonic acid sodium salt;8,8'-[Carbonylbis(imino-4,1-phenylenecarbonylimino-4,1-phenylenecarbonylimino)]bis-1,3,5-naphthalenetrisulfonicacidhexasodiumsalt;8,8'-[CARBONYLBIS(IMINO-4,1-PHENYLENECARBONYLIMINO-4,1-PHENYLENECARBONYLIMINO)]BIS-1,3,5-NAPHTHALENETRISULFONIC ACID HEXASODIUM SALT
- CBNumber:
- CB6135641
- Molecular Formula:
- C49H37N6NaO23S6
- Molecular Weight:
- 1293.2
- MDL Number:
- MFCD01861187
- MOL File:
- 202983-32-2.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| NF279 - CAS 202983-32-2 - Calbiochem A suramin analog that acts as a highly selective, competitive, and reversible ATP-antagonist of P2X receptor (IC /KB ~ 1 μM in smooth muscle). |
480418 | 5mg | $235 |
| NF 279 | 460698 | 10mg | $468 |
| NF 279 | 460698 | 50mg | $1557 |
| NF 279 Asreported | 255973 | 10mg | $466 |
| NF 279 Asreported | 255973 | 50mg | $1281 |
NF 279 price More Price(30)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 480418 | NF279 - CAS 202983-32-2 - Calbiochem A suramin analog that acts as a highly selective, competitive, and reversible ATP-antagonist of P2X receptor (IC /KB ~ 1 μM in smooth muscle). |
202983-32-2 | 5mg | $235 | 2026-04-30 | Buy |
| Usbiological | 460698 | NF 279 | 202983-32-2 | 10mg | $468 | 2026-06-03 | Buy |
| Usbiological | 460698 | NF 279 | 202983-32-2 | 50mg | $1557 | 2026-06-03 | Buy |
| Usbiological | 255973 | NF 279 Asreported | 202983-32-2 | 10mg | $466 | 2026-06-03 | Buy |
| Usbiological | 255973 | NF 279 Asreported | 202983-32-2 | 50mg | $1281 | 2026-06-03 | Buy |
NF 279 Chemical Properties,Uses,Production
Uses
NF 279 is a potent and selective P2X1 antagonist.
General Description
A suramin analog that acts as a highly selective, competitive, and reversible ATP-antagonist of P2X receptor (IC50/KB ~1 μM in smooth muscle). Effectively discriminates between P2Y and P2X receptors with no discernible effects on α1A adrenoceptors, adenosine A1 and A2B receptors, histamine H1, muscarinic M3 and neuronal nicotinic acetylcholine receptors. Displays a selectivity profile of P2X1 >P2X2 >P2X3 >P2X4 (IC50 = 19 nM, 770 nM, 1.62 μM and >300 μM, respectively) in Xenopus oocytes pre-incubated with ATP. In rat and human tissues, exhibits a potency profile of rat P2X1 > human P2X1 rat P2X2 > rat P2X3 ~human P2X7 human P2X4. Not degraded by ecto-nucleotidases.
Biological Activity
A potent and selective P2X 1 antagonist (IC 50 = 19 nM). Displays good selectivity over P2X 2 ,(IC 50 = 0.76 μ M), P2X 3 (IC 50 = 1.62 μ M), P2X 4 (IC 50 > 300 μ M), P2Y receptors and ecto-nucleotidases.
Biochem/physiol Actions
Cell permeable: yes
storage
Store at -20°C
NF 279 Preparation Products And Raw materials
Raw materials
Preparation Products
NF 279 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Career Henan Chemica Co | +86-0371-86658258 +86-13203830695 | laboratory@coreychem.com | China | 30224 | 58 |
| Alfa Chemistry | +1-5166625404; | Info@alfa-chemistry.com | United States | 20000 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 +86-15355479329 | market18@leapchem.com | China | 43333 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15838 | 69 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 9920 | 65 |
| AdooQ BioScience, LLC | +1 (866) 930-6790 | info@adooq.com | United States | 2782 | 58 |
| Jinan Mingya Medical Technology Co., Ltd. | 0531-85828981 | 864598798@qq.com | China | 588 | 58 |
| AdooQ Bioscience CHINA | 025-58849295 | info@adooq.cn | China | 2990 | 60 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51395 | 80 |
| Changzhou Chenhong Biotechnology Co., Ltd. | +86-0519-85788828 +86-13775037613 | sales@chemrenpharm.com | China | 4061 | 58 |
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