R 75317
- CAS No.
- 115406-25-2
- Chemical Name:
- R 75317
- Synonyms
- R 75317;Thiazolium, 3-[(7R)-4-hydroxy-7-(3-isoxazolyloxy)-4-oxido-10-oxo-3,5,9-trioxa-11-aza-4-phosphaoctacos-1-yl]-, inner salt
- CBNumber:
- CB61363568
- Molecular Formula:
- C29H50N3O8PS
- Molecular Weight:
- 631.76
- MDL Number:
- MOL File:
- 115406-25-2.mol
- MSDS File:
- SDS
R 75317 Chemical Properties, Uses, Production
Description
R 75317 is a Platelet-activating factor (PAF) antagonist.
Uses
R-75317 is a specific platelet-activating factor (PAF) antagonist. R-75317 can prevent the decline in creatinine clearance (Ccr) in a rat model of glomerulonephritis induced by the injection of antibodies extracted from rabbits against rat glomerular basement membrane (GBM) antigens, delay the onset of proteinuria, and improve glomerular hypertrophy, mesangial matrix proliferation, and interstitial fibrosis. R-75317 may be useful in the study of glomerulonephritis[1].
References
[1] Miyamoto M, et al. The effects of R-75,317 on antiglomerular basement membrane glomerulonephritis in rats. Lipids. 1991 Dec;26(12):1316-9. doi: 10.1007/BF02536556. DOI:10.1007/BF02536556
R 75317 Preparation Products And Raw materials
Raw materials
Preparation Products
R 75317 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 | marketing@targetmol.com | United States | 32431 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| TargetMol Chemicals Inc. | 13564774135 | marketing@targetmol.com | United States | 19950 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
