ChemicalBook >> CAS DataBase List >>(5S,6R,7R,8S)-5,6,7,8-Tetrahydro-7,8-dihydroxy-2-[2-(3-phenoxyphenyl)ethyl]-6-(2-phenylethoxy)imidazo[1,2-a]pyridine-5-carboxylic acid

(5S,6R,7R,8S)-5,6,7,8-Tetrahydro-7,8-dihydroxy-2-[2-(3-phenoxyphenyl)ethyl]-6-(2-phenylethoxy)imidazo[1,2-a]pyridine-5-carboxylic acid

(5S,6R,7R,8S)-5,6,7,8-Tetrahydro-7,8-dihydroxy-2-[2-(3-phenoxyphenyl)ethyl]-6-(2-phenylethoxy)imidazo[1,2-a]pyridine-5-carboxylic acid structure

CAS No.: 2876926-29-1

Chemical Name:: (5S,6R,7R,8S)-5,6,7,8-Tetrahydro-7,8-dihydroxy-2-[2-(3-phenoxyphenyl)ethyl]-6-(2-phenylethoxy)imidazo[1,2-a]pyridine-5-carboxylic acid

Synonyms: HPSE1-IN-1;(5S,6R,7R,8S)-5,6,7,8-Tetrahydro-7,8-dihydroxy-2-[2-(3-phenoxyphenyl)ethyl]-6-(2-phenylethoxy)imidazo[1,2-a]pyridine-5-carboxylic acid

CBNumber:: CB613804381

Molecular Formula:: C30H30N2O6

Molecular Weight:: 514.57

MDL Number:

MOL File:: 2876926-29-1.mol

Last updated:2025-04-17 18:22:24

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(5S,6R,7R,8S)-5,6,7,8-Tetrahydro-7,8-dihydroxy-2-[2-(3-phenoxyphenyl)ethyl]-6-(2-phenylethoxy)imidazo[1,2-a]pyridine-5-carboxylic acid Properties

Boiling point	741.1±60.0 °C(Predicted)
Density	1.31±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
pka	2.60±0.70(Predicted)

(5S,6R,7R,8S)-5,6,7,8-Tetrahydro-7,8-dihydroxy-2-[2-(3-phenoxyphenyl)ethyl]-6-(2-phenylethoxy)imidazo[1,2-a]pyridine-5-carboxylic acid Chemical Properties, Uses, Production

Uses

HPSE1-IN-1 (compound 16) is a selective inhibitor of Heparanase-1 (HPSE1) with moderate inhibitory activity against exo-β-d-glucuronidase (GUSβ) and glucocerebrosidase (GBA)[1].

References

[1] Imai Y et al. Discovery of a novel tetrahydroimidazo [1, 2-a] pyridine-5-carboxylic acid derivative as a potent and selective heparanase-1 inhibitor utilizing an improved synthetic approach[J]. Bioorganic & Medicinal Chemistry Letters, 2023: 129543.

(5S,6R,7R,8S)-5,6,7,8-Tetrahydro-7,8-dihydroxy-2-[2-(3-phenoxyphenyl)ethyl]-6-(2-phenylethoxy)imidazo[1,2-a]pyridine-5-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

(5S,6R,7R,8S)-5,6,7,8-Tetrahydro-7,8-dihydroxy-2-[2-(3-phenoxyphenyl)ethyl]-6-(2-phenylethoxy)imidazo[1,2-a]pyridine-5-carboxylic acid Suppliers

Global Suppliers ( 1)

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58

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2876926-29-1 ((5S,6R,7R,8S)-5,6,7,8-Tetrahydro-7,8-dihydroxy-2-[2-(3-phenoxyphenyl)ethyl]-6-(2-phenylethoxy)imidazo[1,2-a]pyridine-5-carboxylic acid) Related Search:

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(5S,6R,7R,8S)-5,6,7,8-Tetrahydro-7,8-dihydroxy-2-[2-(3-phenoxyphenyl)ethyl]-6-(2-phenylethoxy)imidazo[1,2-a]pyridine-5-carboxylic acid HPSE1-IN-1 2876926-29-1