(R)-5-Bromomethyl-2-pyrrolidinone
- CAS No.
- 98612-60-3
- Chemical Name:
- (R)-5-Bromomethyl-2-pyrrolidinone
- Synonyms
- (R)-5-(BroMoMethyl)pyrrolidin-2-one;B50370;(R)-5-BROMOMETHYL;(R)-5-Bromomethyl-2-pyrrolidinone;(5R)-5-(bromomethyl)-2-pyrrolidinone;(5R)-5-(broMoMethyl)pyrrolidin-2-one;[R,(+)]-5α-Bromomethyl-2-pyrrolidone;2-Pyrrolidinone, 5-(bromomethyl)-, (5R)-;[R,(+)]-5α-(Bromomethyl)pyrrolidine-2-one;(R)-5-(Bromomethyl)-2-pyrrolidinone
- CBNumber:
- CB6138167
- Molecular Formula:
- C5H8BrNO
- Molecular Weight:
- 178.03
- MDL Number:
- MFCD06799465
- MOL File:
- 98612-60-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 76-80°C |
|---|---|
| Boiling point | 336.1±15.0 °C(Predicted) |
| Density | 1.541±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| pka | 15.39±0.40(Predicted) |
| form | powder |
| Appearance | White to off-white Solid |
| optical activity | [α]22/D +34.0°, c = 0.5 in ethanol |
| InChI | 1S/C5H8BrNO/c6-3-4-1-2-5(8)7-4/h4H,1-3H2,(H,7,8)/t4-/m1/s1 |
| InChIKey | QFOSFXPTXNRRMF-SCSAIBSYSA-N |
| SMILES | BrC[C@H]1CCC(=O)N1 |
| UNSPSC Code | 12352005 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H317-H319 |
| Precautionary statements | P280-P301+P312+P330-P302+P352-P305+P351+P338 |
| Hazard Codes | Xn |
| Risk Statements | 22-36-43 |
| Safety Statements | 26-36/37 |
| WGK Germany | 3 |
| HS Code | 29339900 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral Eye Irrit. 2 Skin Sens. 1 |
(R)-5-Bromomethyl-2-pyrrolidinone price More Price(60)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 715603 | (R)-5-(Bromomethyl)-2-pyrrolidinone 96% | 98612-60-3 | 250mg | $59.4 | 2023-06-20 | Buy |
| Apolloscientific | OR914328 | (R)-5-Bromomethyl-2-pyrrolidinone >97% | 98612-60-3 | 250mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR914328 | (R)-5-Bromomethyl-2-pyrrolidinone >97% | 98612-60-3 | 1g | $33 | 2026-06-04 | Buy |
| Apolloscientific | OR914328 | (R)-5-Bromomethyl-2-pyrrolidinone >97% | 98612-60-3 | 5g | $134 | 2026-06-04 | Buy |
| Apolloscientific | OR914328 | (R)-5-Bromomethyl-2-pyrrolidinone >97% | 98612-60-3 | 25g | $640 | 2026-06-04 | Buy |
(R)-5-Bromomethyl-2-pyrrolidinone Chemical Properties,Uses,Production
Chemical Properties
White to tan powder
Synthesis
128899-31-0
98612-60-3
General procedure for the synthesis of (R)-5-bromomethyl-2-pyrrolidinone from (R)-(5-oxopyrrolidin-2-yl)methyl 4-methylbenzenesulfonate: To a solution of (R)-(5-oxopyrrolidin-2-yl)methyl 4-methylbenzenesulfonate (5.0 g, 18.5 mmol) in acetone (10 mL) was added lithium bromide (4.8 g, 55.6 mmol) The reaction mixture was stirred at 80°C overnight. Upon completion of the reaction, the solvent was removed under vacuum and the residue was partitioned between water (50 mL) and ethyl acetate (100 mL). The aqueous layer was extracted with ethyl acetate (2 x 100 mL), the organic phases were combined and dried over anhydrous sodium sulfate. The organic phase was concentrated in vacuo and the residue was purified by column chromatography (using conventional basic activated alumina with the eluent being a mixture of dichloromethane and 0.2-1.0% methanol) to give (R)-5-bromomethyl-2-pyrrolidinone (3.0 g, 90%) as a pale yellow liquid.LCMS (Method F): m/z 178/180 (M + H) + (ES+), retention time 2.24 min, with UV activity.
References
[1] Patent: WO2017/21728, 2017, A1. Location in patent: Page/Page column 45; 46
(R)-5-Bromomethyl-2-pyrrolidinone Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Wuhan Chemwish Technology Co., Ltd | 86-027-67849912 | sales@chemwish.com | China | 35884 | 56 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 | |
| Sinopharm Chemical Reagent Co,Ltd. | 86-21-63210123 | sj_scrc@sinopharm.com | China | 9791 | 79 |
| T&W GROUP | 021-61551611 13296011611 | contact@trustwe.com | China | 9884 | 58 |
View Lastest Price from (R)-5-Bromomethyl-2-pyrrolidinone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | (R)-5-BROMOMETHYL-2-PYRROLIDINONE
98612-60-3
|
$3.00 | 1KG | 99% | 100kg | Career Henan Chemical Co |
-
- (R)-5-BROMOMETHYL-2-PYRROLIDINONE
98612-60-3
- $3.00
- 99%
- Career Henan Chemical Co
