(R)-5-BROMOMETHYL-2-PYRROLIDINONE
- CAS No.
- 98612-60-3
- Chemical Name:
- (R)-5-BROMOMETHYL-2-PYRROLIDINONE
- Synonyms
- (R)-5-(BroMoMethyl)pyrrolidin-2-one;B50370;(R)-5-BROMOMETHYL;(R)-5-BROMOMETHYL-2-PYRROLIDINONE;(5R)-5-(bromomethyl)-2-pyrrolidinone;(5R)-5-(broMoMethyl)pyrrolidin-2-one;[R,(+)]-5α-Bromomethyl-2-pyrrolidone;2-Pyrrolidinone, 5-(bromomethyl)-, (5R)-;[R,(+)]-5α-(Bromomethyl)pyrrolidine-2-one;(R)-5-(Bromomethyl)-2-pyrrolidinone
- CBNumber:
- CB6138167
- Molecular Formula:
- C5H8BrNO
- Molecular Weight:
- 178.03
- MDL Number:
- MFCD06799465
- MOL File:
- 98612-60-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| (R)-5-(Bromomethyl)-2-pyrrolidinone 96% | 715603 | 250mg | $59.4 |
| (R)-5-Bromomethyl-2-pyrrolidinone >97% | OR914328 | 250mg | $21 |
| (R)-5-Bromomethyl-2-pyrrolidinone >97% | OR914328 | 1g | $33 |
| (R)-5-Bromomethyl-2-pyrrolidinone >97% | OR914328 | 5g | $134 |
| (R)-5-Bromomethyl-2-pyrrolidinone >97% | OR914328 | 25g | $640 |
| More product size | |||
| Melting point | 76-80°C |
|---|---|
| Boiling point | 336.1±15.0 °C(Predicted) |
| Density | 1.541±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| pka | 15.39±0.40(Predicted) |
| form | powder |
| Appearance | White to off-white Solid |
| optical activity | [α]22/D +34.0°, c = 0.5 in ethanol |
| InChI | 1S/C5H8BrNO/c6-3-4-1-2-5(8)7-4/h4H,1-3H2,(H,7,8)/t4-/m1/s1 |
| InChIKey | QFOSFXPTXNRRMF-SCSAIBSYSA-N |
| SMILES | BrC[C@H]1CCC(=O)N1 |
| UNSPSC Code | 12352005 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H317-H319 |
| Precautionary statements | P280-P301+P312+P330-P302+P352-P305+P351+P338 |
| Hazard Codes | Xn |
| Risk Statements | 22-36-43 |
| Safety Statements | 26-36/37 |
| WGK Germany | 3 |
| HS Code | 29339900 |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral Eye Irrit. 2 Skin Sens. 1 |
(R)-5-BROMOMETHYL-2-PYRROLIDINONE price More Price(80)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 715603 | (R)-5-(Bromomethyl)-2-pyrrolidinone 96% | 98612-60-3 | 250mg | $59.4 | 2023-06-20 | Buy |
| Apolloscientific | OR914328 | (R)-5-Bromomethyl-2-pyrrolidinone >97% | 98612-60-3 | 250mg | $21 | 2026-06-04 | Buy |
| Apolloscientific | OR914328 | (R)-5-Bromomethyl-2-pyrrolidinone >97% | 98612-60-3 | 1g | $33 | 2026-06-04 | Buy |
| Apolloscientific | OR914328 | (R)-5-Bromomethyl-2-pyrrolidinone >97% | 98612-60-3 | 5g | $134 | 2026-06-04 | Buy |
| Apolloscientific | OR914328 | (R)-5-Bromomethyl-2-pyrrolidinone >97% | 98612-60-3 | 25g | $640 | 2026-06-04 | Buy |
(R)-5-BROMOMETHYL-2-PYRROLIDINONE Chemical Properties,Uses,Production
Chemical Properties
White to tan powder
Synthesis
128899-31-0
98612-60-3
General procedure for the synthesis of (R)-5-bromomethyl-2-pyrrolidinone from (R)-(5-oxopyrrolidin-2-yl)methyl 4-methylbenzenesulfonate: To a solution of (R)-(5-oxopyrrolidin-2-yl)methyl 4-methylbenzenesulfonate (5.0 g, 18.5 mmol) in acetone (10 mL) was added lithium bromide (4.8 g, 55.6 mmol) The reaction mixture was stirred at 80°C overnight. Upon completion of the reaction, the solvent was removed under vacuum and the residue was partitioned between water (50 mL) and ethyl acetate (100 mL). The aqueous layer was extracted with ethyl acetate (2 x 100 mL), the organic phases were combined and dried over anhydrous sodium sulfate. The organic phase was concentrated in vacuo and the residue was purified by column chromatography (using conventional basic activated alumina with the eluent being a mixture of dichloromethane and 0.2-1.0% methanol) to give (R)-5-bromomethyl-2-pyrrolidinone (3.0 g, 90%) as a pale yellow liquid.LCMS (Method F): m/z 178/180 (M + H) + (ES+), retention time 2.24 min, with UV activity.
References
[1] Patent: WO2017/21728, 2017, A1. Location in patent: Page/Page column 45; 46
(R)-5-BROMOMETHYL-2-PYRROLIDINONE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29812 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418684 +8618949823763 | sales@tnjchem.com | China | 25356 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531151365 | mina@chuanghaibio.com | China | 18126 | 58 |
View Lastest Price from (R)-5-BROMOMETHYL-2-PYRROLIDINONE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | (R)-5-BROMOMETHYL-2-PYRROLIDINONE
98612-60-3
|
$3.00 | 1KG | 99% | 100kg | Career Henan Chemical Co |
-
- (R)-5-BROMOMETHYL-2-PYRROLIDINONE
98612-60-3
- $3.00
- 99%
- Career Henan Chemical Co
