Insulin sensitizer C59
- CAS No.
- 2761446-81-3
- Chemical Name:
- Insulin sensitizer C59
- Synonyms
- GLUT4 activator 2;Insulin sensitizer C59;Tricyclo[3.3.1.13,7]decane-1-carboxamide, N-(4,5-dichloro-2-pyridinyl)-
- CBNumber:
- CB614108093
- Molecular Formula:
- C16H18Cl2N2O
- Molecular Weight:
- 325.23
- MDL Number:
- MOL File:
- 2761446-81-3.mol
- MSDS File:
- SDS
| Boiling point | 491.664±45.00 °C(Press: 760.00 Torr)(predicted) |
|---|---|
| Density | 1.415±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO: 2mg/mL, clear (Warmed) |
| form | powder |
| pka | 9.313±0.50(predicted) |
| color | white to beige |
| UNSPSC Code | 12352200 |
| NACRES | NA.21 |
Insulin sensitizer C59 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 42129 | Insulin Sensitizer C59 ≥98% | 2761446-81-3 | 5mg | $61 | 2026-04-30 | Buy |
| Cayman Chemical | 42129 | Insulin Sensitizer C59 ≥98% | 2761446-81-3 | 10mg | $104 | 2026-04-30 | Buy |
| Cayman Chemical | 42129 | Insulin Sensitizer C59 ≥98% | 2761446-81-3 | 25mg | $213 | 2026-04-30 | Buy |
| ChemScene | CS-1180064 | GLUT4 activator 2 | 2761446-81-3 | 5mg | $65 | 2026-06-04 | Buy |
| ChemScene | CS-1180064 | GLUT4 activator 2 | 2761446-81-3 | 10mg | $104 | 2026-06-04 | Buy |
Insulin sensitizer C59 Chemical Properties, Uses, Production
Uses
GLUT4 activator 2 (C59) is an insulin sensitizer, which can be used for research of diabetic diseases. GLUT4 activator 2 improves glucose uptake and insulin sensitivity in rodents. GLUT4 activator 2 interacts with Unc119 and Unc119B resulting in increased insulin sensitivity and GLUT4 translocation[1].
Biological Activity
Orally available potentiator of insulin action th at significantly improves glucose tolerance in DIO mice; restores insulin-stimulated GLUT4 translocation.
References
[1] Yin TC, et al. Insulin sensitization by small molecules enhancing GLUT4 translocation. Cell Chem Biol. 2023 Aug 17;30(8):933-942.e6. DOI:10.1016/j.chembiol.2023.06.012
Insulin sensitizer C59 Preparation Products And Raw materials
Raw materials
Preparation Products
Insulin sensitizer C59 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16306 | 64 |
| Shanghai Beckham Medical Technology Co., Ltd | 13816613772 | huahero21@sina.com | China | 2994 | 55 |
| Shanghai SuperLan Chemcial Technique Centre | 0-2022843681 15618226720 | chaolaichem@foxmail.com | China | 9996 | 58 |
| Jinan Jiuli Biotechnology Co. , Ltd. | 15865264761 | 486064515@qq.com | China | 5000 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 29874 | 58 |
| Shaoguan Qicheng Biotechnology Co., Ltd | 18122215013 | 780229652@qq.com | China | 1392 | 58 |
| Guangzhou Ruidi Biotechnology Co., Ltd. | 020-82099279 18988941402 | sales@ubiochem.com | China | 9998 | 58 |
