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NLRP3-IN-37

NLRP3-IN-37 structure

CAS No.: 3033054-51-9

Chemical Name:: NLRP3-IN-37

Synonyms: NLRP3-IN-37;Phenol, 2-[8-[(3aS,7aR)-octahydro-6-methyl-1H-pyrrolo[2,3-c]pyridin-1-yl]pyrido[2,3-d]pyridazin-5-yl]-5-(trifluoromethyl)-

CBNumber:: CB614282973

Molecular Formula:: C22H22F3N5O

Molecular Weight:: 429.44

MDL Number:

MOL File:: 3033054-51-9.mol

Last updated:2025-04-17 18:22:24

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NLRP3-IN-37 Properties

Boiling point	586.0±50.0 °C(predicted)
Density	1.350±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka	6.94±0.40(predicted)

NLRP3-IN-37 Chemical Properties, Uses, Production

Uses

NLRP3-IN-37 (Compound 23) is a NLRP3 inhibitor (EC50: 5 nM). NLRP3-IN-37 can be used for NLRP3 related research, such as gout, pseudogout, CAPS, NASH fibrosis, heart failure, idiophathic pericarditis, atopic dermatitis, inflammatory bowel disease, Alzheimer's Disease, Parkinson's Disease and traumatic brain injury[1].

References

[1] Donna A. A, et al. WPhthalazine derivatives useful as inhibitors of nod-like receptor protein 3. Patent.WO2024064245A1.

NLRP3-IN-37 Preparation Products And Raw materials

Raw materials

Preparation Products

NLRP3-IN-37 Suppliers

Global Suppliers ( 1)

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58

Supplier	Advantage
TargetMol Chemicals Inc.	58

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NLRP3-IN-37 Phenol, 2-[8-[(3aS,7aR)-octahydro-6-methyl-1H-pyrrolo[2,3-c]pyridin-1-yl]pyrido[2,3-d]pyridazin-5-yl]-5-(trifluoromethyl)- 3033054-51-9