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ChemicalBook >> CAS DataBase List >>(2S)-3-(4-hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidyl)ethoxy]phenyl]-2H-chromen-7-ol

(2S)-3-(4-hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidyl)ethoxy]phenyl]-2H-chromen-7-ol

(2S)-3-(4-hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidyl)ethoxy]phenyl]-2H-chromen-7-ol Structure
(2S)-3-(4-hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidyl)ethoxy]phenyl]-2H-chromen-7-ol structure
CAS No.
252555-01-4
Chemical Name:
(2S)-3-(4-hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidyl)ethoxy]phenyl]-2H-chromen-7-ol
Synonyms
ACOLBIFENE (hydrochloride);BYQDPIXWTVEVEA-JMAPEOGHSA-N;(2S)-3-(4-hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidyl)ethoxy]phenyl]-2H-chromen-7-ol;(2S)-3-(4-hydroxyphenyl)-4-methyl-2-[4-(2-piperidin-1-ylethoxy)phenyl]-2H-chromen-7-ol,hydrochloride
CBNumber:
CB61458796
Molecular Formula:
C29H31NO4
Molecular Weight:
0
MDL Number:
MFCD32645228
MOL File:
252555-01-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-27 17:00:41
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(2S)-3-(4-hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidyl)ethoxy]phenyl]-2H-chromen-7-ol Properties

solubility DMSO: 180 mg/mL (364.36 mM)
form Solid
color White to yellow
NCI Dictionary of Cancer Terms acolbifene hydrochloride
FDA UNII KXC7811DBY

(2S)-3-(4-hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidyl)ethoxy]phenyl]-2H-chromen-7-ol price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth CKA55501 Acolbifene hydrochloride 252555-01-4 25mg $1119.5 2026-06-04 Buy
Biosynth CKA55501 Acolbifene hydrochloride 252555-01-4 50mg $1557.5 2026-06-04 Buy
Biosynth CKA55501 Acolbifene hydrochloride 252555-01-4 100mg $2492 2026-06-04 Buy
ChemScene CS-0006117 Acolbifene hydrochloride 99.00% 252555-01-4 5mg $195 2026-06-04 Buy
ChemScene CS-0006117 Acolbifene hydrochloride 99.00% 252555-01-4 10mg $314 2026-06-04 Buy
Product number Packaging Price Buy
CKA55501 25mg $1119.5 Buy
CKA55501 50mg $1557.5 Buy
CKA55501 100mg $2492 Buy
CS-0006117 5mg $195 Buy
CS-0006117 10mg $314 Buy

(2S)-3-(4-hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidyl)ethoxy]phenyl]-2H-chromen-7-ol Chemical Properties,Uses,Production

Uses

Prevention or treatment of breast and uterine proliferation or cancer.

in vivo

Acolbifene (ACOL) reduces food intake and strongly decreases cholesterolemia in rats fed a cholesterol-free diet[2].
Acolbifene (ACOL) reduces food intake (16%) and weight gain (45%, mainly fat) similarly in both dietary cohorts[2].

Animal Model:Female Sprague-Dawley rats (n = 42) initially weighing 175-200 g[2].
Dosage:2.5 mg/kg.
Administration:Oral gavage, once daily for 21 d.
Result:Prevents tumor growth in rats.

IC 50

ERα: 2 nM (IC50, E2-induced transcriptional activity); ERβ: 0.4 nM (IC50, E2-induced transcriptional activity)

(2S)-3-(4-hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidyl)ethoxy]phenyl]-2H-chromen-7-ol synthesis

182167-02-8
252555-01-4
Synthesis of (2S)-3-(4-hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidyl)ethoxy]phenyl]-2H-chromen-7-ol from Sch 57068

(2S)-3-(4-hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidyl)ethoxy]phenyl]-2H-chromen-7-ol Preparation Products And Raw materials

Raw materials

Sch 57068

Preparation Products

(2S)-3-(4-hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidyl)ethoxy]phenyl]-2H-chromen-7-ol Suppliers

Global( 18)Suppliers
Supplier Tel Email Country ProdList Advantage
SPIRO PHARMA eric_feng1954@126.com China 9239 55
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Jinan elephant international trading co., LTD 13006575422@163.com China 6347 58
Jinan Yaoyan Pharmaceutical Co., Ltd. jnyaoyan@163.com China 3057 58
Nanjing Meihao Pharmaceutical Technology Co., Ltd. meitaochem@126.com meitaochem@126.com China 19087 58
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 psaitong@jm-bio.com China 27626 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Supplier Advantage
SPIRO PHARMA 55
Shanghai YuanYe Biotechnology Co., Ltd. 60
Jinan elephant international trading co., LTD 58
Jinan Yaoyan Pharmaceutical Co., Ltd. 58
Nanjing Meihao Pharmaceutical Technology Co., Ltd. 58
BOC Sciences 58
TargetMol Chemicals Inc. 58
Beijing Jin Ming Biotechnology Co., Ltd. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58

View Lastest Price from (2S)-3-(4-hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidyl)ethoxy]phenyl]-2H-chromen-7-ol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Acolbifene Hydrochloride pictures 2026-07-27 Acolbifene Hydrochloride
252555-01-4
 $789.00-1110.00 10g TargetMol Chemicals Inc.

252555-01-4((2S)-3-(4-hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidyl)ethoxy]phenyl]-2H-chromen-7-ol)Related Search:

Anti-cancer compound library ER beta / ESR2 Protein, Human (His) Clinical Compound Library ER alpha / ESR1 Protein, Human (His)
ACOLBIFENE (hydrochloride) BYQDPIXWTVEVEA-JMAPEOGHSA-N (2S)-3-(4-hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidyl)ethoxy]phenyl]-2H-chromen-7-ol (2S)-3-(4-hydroxyphenyl)-4-methyl-2-[4-(2-piperidin-1-ylethoxy)phenyl]-2H-chromen-7-ol,hydrochloride 252555-01-4