Tetraethylammonium fluoride dihydrate
- CAS No.
- 665-46-3
- Chemical Name:
- Tetraethylammonium fluoride dihydrate
- Synonyms
- TETRAETHYLAMMONIUM FLUORIDE;Tetraethylazanium fluoride;[E4N]F;Tetraethylaminium·fluoride;TetraethylaMMoniuM Fluoride N,N,N-TRIETHYL-ETHANAMINIUFLUORIDE;N,N,N-Triethylethanaminium·fluoride;Tetraethylammonium fluoride 2-hydrate;Tetraethylammonium fluoride dihydrate;Tetraethylammonium Fluoride Hydrate>
- CBNumber:
- CB6148887
- Molecular Formula:
- C8H24FNO2
- Molecular Weight:
- 185.28
- MDL Number:
- MFCD00011826
- MOL File:
- 665-46-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 80 °C (decomp) |
|---|---|
| storage temp. | Inert atmosphere,Room Temperature |
| InChI | InChI=1S/C8H20N.FH.2H2O/c1-5-9(6-2,7-3)8-4;;;/h5-8H2,1-4H3;1H;2*1H2/q+1;;;/p-1 |
| InChIKey | HRTKQUHFGZFPPF-UHFFFAOYSA-M |
| SMILES | [N+](CC)(CC)(CC)CC.[F-].[H]O[H].[H]O[H] |
| CAS DataBase Reference | 665-46-3(CAS DataBase Reference) |
| EPA Substance Registry System | Tetraethylammonium fluoride (665-46-3) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H319-H335-H332-H315-H302-H312 | |||||||||
| Precautionary statements | P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P-P264-P270-P301+P312-P330-P501-P261-P271-P304+P340-P312-P280-P302+P352-P312-P322-P363-P501 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 20/21/22-36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 3-9 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 2921199990 | |||||||||
| NFPA 704 |
|
Tetraethylammonium fluoride dihydrate price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | T0838 | Tetraethylammonium Fluoride Hydrate >98.0%(T) | 665-46-3 | 5g | $129 | 2025-07-31 | Buy |
| TCI Chemical | T0838 | Tetraethylammonium Fluoride Hydrate >98.0%(T) | 665-46-3 | 25g | $389 | 2025-07-31 | Buy |
| Apolloscientific | PC903855 | Tetraethylammonium fluoride 98% | 665-46-3 | 5g | $21 | 2026-06-04 | Buy |
| Apolloscientific | PC903855 | Tetraethylammonium fluoride 98% | 665-46-3 | 25g | $28 | 2026-06-04 | Buy |
| Apolloscientific | PC903855 | Tetraethylammonium fluoride 98% | 665-46-3 | 100g | $82 | 2026-06-04 | Buy |
Tetraethylammonium fluoride dihydrate Chemical Properties,Uses,Production
Uses
Tetraethylammonium Fluoride Dihydrate is an analog of Tetraethylammonium Chloride (T292700). Tetraethylammonium Chloride can be used as a source of tetraethylammonium ions for various pharmaceutical studies and has the ability to block K+ channels in various tissues. Tetraethylammonium Chloride can also block the transmission of nervous impulses across autonomic ganglions.
Synthesis
68-05-3
665-46-3
(1) dissolve 10 g of tetraethylammonium iodide with 99% purity in 25 mL of distilled water, add 60 mL of hydrofluoric acid with a mass concentration of 35%, seal and heat at 50 °C with stirring; (2) ensure that the raw materials are fully reacted for at least 3 h, and then raise the temperature to 110 °C to evaporate the excess hydrogen fluoride gas and by-product hydrogen, and absorb the exhaust gas using calcium oxide, taking care to avoid tetraethylammonium fluoride ionic liquid dehydration; (3) diluting the undehydrated tetraethylammonium fluoride ionic liquid with distilled water, ensuring that the volume ratio of the tetraethylammonium fluoride ionic liquid to distilled water was less than 1:50. AgNO3 solution was added to the diluted solution, and if precipitation was observed to be generated, 20 mL of hydrofluoric acid was continued to be added, and steps (1) and (2) were repeated until no precipitate was generated in order to purify the tetraethylammonium fluoride ionic liquid; (4) The unpurified tetraethylammonium fluoride ionic liquid was dried under high vacuum at 120°C for at least 48 hours to remove water and residual hydrogen fluoride. The viscous liquid obtained needs to be diluted with distilled water to ensure that the volume ratio of viscous liquid to distilled water is less than 1:50, sealed and heated at 60°C, and the residual hydrogen fluoride concentration is detected using a hydrogen detector. If the reading is more than 0.1 ppm, then continue to dry in high vacuum at 120 ℃ until the concentration of hydrogen fluoride is less than 0.1 ppm When the concentration of hydrogen fluoride is detected to be less than 0.1 ppm, the resulting liquid is tetraethylammonium fluoride ionic liquid, and the weight of the final product is 5.67 g. The final product weighs 5.67 g. The final liquid is then dried in high vacuum at 120 ℃ until the concentration of hydrogen fluoride is less than 0.1 ppm.
References
[1] Patent: CN103992275, 2016, B. Location in patent: Paragraph 0264; 0265; 0266; 0267; 0268; 0269
Tetraethylammonium fluoride dihydrate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Kaisai Chemical Co., Ltd | 021-33516722 13701817765 | kaisaichem@163.com | China | 4604 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
| XiaoGan ShenYuan ChemPharm co,ltd | 15527621225; 15527621225 | 1791901229@qq.com | China | 6746 | 52 |
| Shandong Xiya Chemical Co., Ltd | 13355009207 13355009207 | 3007715519@qq.com | China | 18722 | 57 |
| Syntechem Co.,Ltd | info@syntechem.com | China | 12973 | 57 |
View Lastest Price from Tetraethylammonium fluoride dihydrate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-11 | Tetraethylammonium fluoride dihydrate
665-46-3
|
1KG | 98%min | 30tons/month | WUHAN FORTUNA CHEMICAL CO., LTD | ||
 |
2026-09-02 | Tetraethyl Ammonium Fluoride
665-46-3
|
$5.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd | ||
 |
2025-05-26 | MCU
665-46-3
|
$67.00 | 1kg | 0.99 | 5000 tons | Hebei Fengjia New Material Co., Ltd |
-
- Tetraethylammonium fluoride dihydrate
665-46-3
- $0.00
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- Tetraethyl Ammonium Fluoride
665-46-3
- $5.00
- 99%
- Henan Fengda Chemical Co., Ltd
-
- MCU
665-46-3
- $67.00
- 0.99
- Hebei Fengjia New Material Co., Ltd
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