5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt
- CAS No.
- 888504-28-7
- Chemical Name:
- 5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt
- Synonyms
- 5-Methyl-;Raltegravir Oxadiazole Impurity;5-Methyl-1,3,4-oxadiazole-2-carboxylate;4-oxadiazole-2-carboxylic acid potassium salt;5-methyl-1,3,4-oxadiazole-2-carboxylic acid potassium;potassiuM 5-Methyl-1,3,4-oxadiazole-2-carboxylic acid;5-Methyl-1,3,4-oxadiazole-2-carboxylate,potassium salt;Potassium salt, 5-methyl-1,3, 4-oxadiazole-2-carboxylate;5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt;7,8-difluoro-6,11-dihydro-dibenzo [b, e] thieno-11-alcohol
- CBNumber:
- CB61518647
- Molecular Formula:
- C4H3KN2O3
- Molecular Weight:
- 166.18
- MDL Number:
- MFCD08060085
- MOL File:
- 888504-28-7.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| Potassium 5-Methyl-1,3,4-oxadiazole-2-carboxylate >98.0%(HPLC)(T) | P2220 | 200mg | $114 |
| Potassium 5-Methyl-1,3,4-oxadiazole-2-carboxylate >98.0%(HPLC)(T) | P2220 | 1g | $354 |
| 5-Methyl-[1,3,4]oxadiazole-2-carboxylic acid, potassium salt Asreported | 284616 | 5g | $326 |
| 5-Methyl-[1,3,4]oxadiazole-2-carboxylic acid, potassium salt Asreported | 284616 | 10g | $435 |
| 5-Methyl-[1,3,4]oxadiazole-2-carboxylic acid, potassium salt Asreported | 284616 | 25g | $573 |
| More product size | |||
| Melting point | 258.3 °C (decomp) |
|---|---|
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| solubility | Water |
| form | Solid |
| color | Off-White |
| InChI | InChI=1S/C4H4N2O3.K/c1-2-5-6-3(9-2)4(7)8;/h1H3,(H,7,8);/q;+1/p-1 |
| InChIKey | BRHMYHXNUGVBCU-UHFFFAOYSA-M |
| SMILES | C1(C(=O)[O-])OC(C)=NN=1.[K+] |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS08 |
|---|---|
| Signal word | Warning |
| Hazard statements | H361 |
| Precautionary statements | P201-P202-P281-P308+P313-P405-P501 |
| WGK Germany | 3 |
| HS Code | 2918.99.4700 |
| REACH Registrations | Active |
5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt price More Price(64)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | P2220 | Potassium 5-Methyl-1,3,4-oxadiazole-2-carboxylate >98.0%(HPLC)(T) | 888504-28-7 | 200mg | $114 | 2026-04-30 | Buy |
| TCI Chemical | P2220 | Potassium 5-Methyl-1,3,4-oxadiazole-2-carboxylate >98.0%(HPLC)(T) | 888504-28-7 | 1g | $354 | 2026-04-30 | Buy |
| Usbiological | 284616 | 5-Methyl-[1,3,4]oxadiazole-2-carboxylic acid, potassium salt Asreported | 888504-28-7 | 5g | $326 | 2026-06-03 | Buy |
| Usbiological | 284616 | 5-Methyl-[1,3,4]oxadiazole-2-carboxylic acid, potassium salt Asreported | 888504-28-7 | 10g | $435 | 2026-06-03 | Buy |
| Usbiological | 284616 | 5-Methyl-[1,3,4]oxadiazole-2-carboxylic acid, potassium salt Asreported | 888504-28-7 | 25g | $573 | 2026-06-03 | Buy |
5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt Chemical Properties,Uses,Production
Chemical Properties
Off-White Solid
Uses
An intermediate in the preparation of HIV-integrase inhibitors.
Synthesis
37641-36-4
888504-28-7
Synthesis of potassium 5-methyl-1,3,4-oxadiazole-2-carboxylate (19b): potassium triethylsilanolate (411 mg, 3.20 mmol) was suspended in ethyl ether at room temperature and stirred to form a slurry. Subsequently, ethyl 5-methyl-1,3,4-oxadiazole-2-carboxylate (0.50 g, 3.20 mmol) was added at once. The reaction immediately produced a precipitate, which changed color from white to off-white. The precipitate was separated by filtration, washed with ether and dried to give the title compound as an off-white solid (580 mg, quantitative yield).1H NMR (300 MHz, CDCl3): δ 2.61 (3H, s). 13C NMR (75 MHz, D2O): δ 166.7, 161.3, 159.3, 10.4.
References
[1] Patent: US2009/35324, 2009, A1. Location in patent: Page/Page column 12
[2] Patent: WO2016/127859, 2016, A1. Location in patent: Paragraph 00194
[3] Patent: CN106349233, 2017, A. Location in patent: Paragraph 0243; 0274; 0275; 0276
[4] Patent: WO2006/60711, 2006, A2. Location in patent: Page/Page column 30-31
[5] Patent: WO2006/60731, 2006, A2. Location in patent: Page/Page column 35-36
5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shandong Dinghao Biological Technology Co. LTD | +86-86-18300239 +8618300239268 | sales@sddhpharm.com | China | 101 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 | faithe@yan-xi.com | China | 5853 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20121 | 58 |
| Hebei Zhuanglai Chemical Trading Co Ltd | +86-16264648883 | niki@zlchemi.com | China | 7245 | 58 |
| Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29640 | 60 |
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1803 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21585 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29812 | 58 |
| Jinan Chenghui-Shuangda Chemical Co.,Ltd | +86-531-58897082 | ericqiao@jnchsd.com | CHINA | 158 | 58 |
View Lastest Price from 5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-07-09 | 5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt
888504-28-7
|
$2.00-10.00 | 1KG | 99% | Henan Fengda Chemical Co., Ltd | ||
![]() |
2025-06-20 | 5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt
888504-28-7
|
$40.00 | 1kg | 0.99 | 10 tons | Hebei Yanxi Chemical Co., Ltd. | |
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2025-05-23 | 5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt
888504-28-7
|
$10.00 | 1kg | 99% | 20 ton | Hebei Zhuanglai Chemical Trading Co Ltd |
-

- 5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt
888504-28-7
- $2.00-10.00
- 99%
- Henan Fengda Chemical Co., Ltd
-

- 5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt
888504-28-7
- $40.00
- 0.99
- Hebei Yanxi Chemical Co., Ltd.
-

- 5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt
888504-28-7
- $10.00
- 99%
- Hebei Zhuanglai Chemical Trading Co Ltd
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