ChemicalBook >> CAS DataBase List >>5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt

5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt

CAS No.
888504-28-7
Chemical Name:
5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt
Synonyms
5-Methyl-;Raltegravir Oxadiazole Impurity;5-Methyl-1,3,4-oxadiazole-2-carboxylate;4-oxadiazole-2-carboxylic acid potassium salt;5-methyl-1,3,4-oxadiazole-2-carboxylic acid potassium;potassiuM 5-Methyl-1,3,4-oxadiazole-2-carboxylic acid;5-Methyl-1,3,4-oxadiazole-2-carboxylate,potassium salt;Potassium salt, 5-methyl-1,3, 4-oxadiazole-2-carboxylate;5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt;7,8-difluoro-6,11-dihydro-dibenzo [b, e] thieno-11-alcohol
CBNumber:
CB61518647
Molecular Formula:
C4H3KN2O3
Molecular Weight:
166.18
MDL Number:
MFCD08060085
MOL File:
888504-28-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-28 03:20:15
Product description Number Pack Size Price
Potassium 5-Methyl-1,3,4-oxadiazole-2-carboxylate >98.0%(HPLC)(T) P2220 200mg $114
Potassium 5-Methyl-1,3,4-oxadiazole-2-carboxylate >98.0%(HPLC)(T) P2220 1g $354
5-Methyl-[1,3,4]oxadiazole-2-carboxylic acid, potassium salt Asreported 284616 5g $326
5-Methyl-[1,3,4]oxadiazole-2-carboxylic acid, potassium salt Asreported 284616 10g $435
5-Methyl-[1,3,4]oxadiazole-2-carboxylic acid, potassium salt Asreported 284616 25g $573
More product size

5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt Properties

Melting point 258.3 °C (decomp)
storage temp. Inert atmosphere,Store in freezer, under -20°C
solubility Water
form Solid
color Off-White
InChI InChI=1S/C4H4N2O3.K/c1-2-5-6-3(9-2)4(7)8;/h1H3,(H,7,8);/q;+1/p-1
InChIKey BRHMYHXNUGVBCU-UHFFFAOYSA-M
SMILES C1(C(=O)[O-])OC(C)=NN=1.[K+]

SAFETY

Risk and Safety Statements

Symbol(GHS)  Health Hazard (GHS08)
GHS08
Signal word  Warning
Hazard statements  H361
Precautionary statements  P201-P202-P281-P308+P313-P405-P501
WGK Germany  3
HS Code  2918.99.4700
REACH Registrations Active

5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt price More Price(64)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical P2220 Potassium 5-Methyl-1,3,4-oxadiazole-2-carboxylate >98.0%(HPLC)(T) 888504-28-7 200mg $114 2026-04-30 Buy
TCI Chemical P2220 Potassium 5-Methyl-1,3,4-oxadiazole-2-carboxylate >98.0%(HPLC)(T) 888504-28-7 1g $354 2026-04-30 Buy
Usbiological 284616 5-Methyl-[1,3,4]oxadiazole-2-carboxylic acid, potassium salt Asreported 888504-28-7 5g $326 2026-06-03 Buy
Usbiological 284616 5-Methyl-[1,3,4]oxadiazole-2-carboxylic acid, potassium salt Asreported 888504-28-7 10g $435 2026-06-03 Buy
Usbiological 284616 5-Methyl-[1,3,4]oxadiazole-2-carboxylic acid, potassium salt Asreported 888504-28-7 25g $573 2026-06-03 Buy
Product number Packaging Price Buy
P2220 200mg $114 Buy
P2220 1g $354 Buy
284616 5g $326 Buy
284616 10g $435 Buy
284616 25g $573 Buy

5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Uses

An intermediate in the preparation of HIV-integrase inhibitors.

Synthesis

5-METHYL-[1,3,4]OXADIAZOLE-2-CARBOXYLIC ACID ETHYL ESTER

37641-36-4

5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt

888504-28-7

Synthesis of potassium 5-methyl-1,3,4-oxadiazole-2-carboxylate (19b): potassium triethylsilanolate (411 mg, 3.20 mmol) was suspended in ethyl ether at room temperature and stirred to form a slurry. Subsequently, ethyl 5-methyl-1,3,4-oxadiazole-2-carboxylate (0.50 g, 3.20 mmol) was added at once. The reaction immediately produced a precipitate, which changed color from white to off-white. The precipitate was separated by filtration, washed with ether and dried to give the title compound as an off-white solid (580 mg, quantitative yield).1H NMR (300 MHz, CDCl3): δ 2.61 (3H, s). 13C NMR (75 MHz, D2O): δ 166.7, 161.3, 159.3, 10.4.

References

[1] Patent: US2009/35324, 2009, A1. Location in patent: Page/Page column 12
[2] Patent: WO2016/127859, 2016, A1. Location in patent: Paragraph 00194
[3] Patent: CN106349233, 2017, A. Location in patent: Paragraph 0243; 0274; 0275; 0276
[4] Patent: WO2006/60711, 2006, A2. Location in patent: Page/Page column 30-31
[5] Patent: WO2006/60731, 2006, A2. Location in patent: Page/Page column 35-36

5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt Preparation Products And Raw materials

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Shandong Dinghao Biological Technology Co. LTD
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View Lastest Price from 5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt pictures 2026-07-09 5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt
888504-28-7
$2.00-10.00 1KG 99% Henan Fengda Chemical Co., Ltd
5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt pictures 2025-06-20 5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt
888504-28-7
$40.00 1kg 0.99 10 tons Hebei Yanxi Chemical Co., Ltd.
5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt pictures 2025-05-23 5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt
888504-28-7
$10.00 1kg 99% 20 ton Hebei Zhuanglai Chemical Trading Co Ltd
5-Methyl-1,3,4-oxadiazole-2-carboxylic acid potassium salt 4-oxadiazole-2-carboxylic acid potassium salt 5-Methyl- 5-methyl-1,3,4-oxadiazole-2-carboxylic acid(SALTDATA: FREE) 5-methyl-1,3,4-oxadiazole-2-carboxylic acid potassium 5-Methyl-1,3,4-oxadiazole-2-carboxylic acid, potassiuM salt (1:1) potassiuM 5-Methyl-1,3,4-oxadiazole-2-carboxylic acid 1,3,4-Oxadiazole-2-carboxylic acid, 5-Methyl-, potassiuM salt 8. 1,3,4-Oxadiazole-2-carboxylicacid, 5-methyl-, potassium salt (1:1) 5-Methyl-1,3,4-oxadiazole-2-carboxylate,potassium salt 5-Methyl-1,3,4-oxadiazole-2-carboxylate 1,3,4-Oxadiazole-2-carboxylicacid, 5-Methyl-, potassiuM salt (1:1) 5-Methyl-l,3,4-oxadiazole-2-carboxylic acid potassium salt(Raltegravir) Raltegravir Oxadiazole Impurity Potassium salt, 5-methyl-1,3, 4-oxadiazole-2-carboxylate 7,8-difluoro-6,11-dihydro-dibenzo [b, e] thieno-11-alcohol 5-Methyl-1,3,4-oxadiazole-2-carboxilic acid potassium salt. 888504-28-7 C4H3KN2O3 Heterocycles Intermediates & Fine Chemicals Pharmaceuticals