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(E)-(+/-)-2-Amino-4-methyl-5-phosphono-3-pentenoic acid ethyl ester

(E)-(+/-)-2-Amino-4-methyl-5-phosphono-3-pentenoic acid ethyl ester structure

CAS No.: 127910-32-1

Chemical Name:: (E)-(+/-)-2-Amino-4-methyl-5-phosphono-3-pentenoic acid ethyl ester

Synonyms: CGP 39551;CGP 39551, competitive NMDA antagonist;2-Amino-4-methyl-5-phosphono-3 pentenoic acid carboxyethyl ester;(E)-(4-Amino-5-ethoxy-2-methyl-5-oxopent-2-en-1-yl)phosphonic acid;(E)-(+/-)-2-Amino-4-methyl-5-phosphono-3-pentenoic acid ethyl ester;(E)-(+/-)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID ETHYLESTHER;3-Pentenoic acid, 2-amino-4-methyl-5-phosphono-, 1-ethyl ester, (3E)-;3-Pentenoic acid, 2-amino-4-methyl-5-phosphono-, 1-ethyl ester, (E)-(+-)-

CBNumber:: CB6155364

Molecular Formula:: C8H16NO5P

Molecular Weight:: 237.19

MDL Number:: MFCD00882474

MOL File:: 127910-32-1.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-09-12 18:53:57

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(E)-(+/-)-2-Amino-4-methyl-5-phosphono-3-pentenoic acid ethyl ester Properties

Boiling point	434.1±55.0 °C(Predicted)
Density	1.312±0.06 g/cm3(Predicted)
storage temp.	Desiccate at +4°C
solubility	H2O: soluble15mg/mL, clear
form	powder
pka	2.30±0.10(Predicted)
color	white to beige
Water Solubility	Soluble to 100 mM in water
EWG's Food Scores	1

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS06
Signal word	Danger
Hazard statements	H301
Precautionary statements	P301+P310
Hazard Codes	T
Risk Statements	25
Safety Statements	45
RIDADR	UN 2811 6.1 / PGIII
WGK Germany	3

(E)-(+/-)-2-Amino-4-methyl-5-phosphono-3-pentenoic acid ethyl ester price More Price(18)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	SML0058	CGP 39551 ≥98% (HPLC)	127910-32-1	5mg	$95.7	2022-05-15	Buy
Sigma-Aldrich	SML0058	CGP 39551 ≥98% (HPLC)	127910-32-1	25mg	$388	2022-05-15	Buy
Usbiological	444249	CGP 39551	127910-32-1	10mg	$425	2026-06-03	Buy
Usbiological	444249	CGP 39551	127910-32-1	25mg	$672	2026-06-03	Buy
Usbiological	254937	CGP 39551 Asreported	127910-32-1	10mg	$446	2026-06-03	Buy

Product number	Packaging	Price	Buy
SML0058	5mg	$95.7	Buy
SML0058	25mg	$388	Buy
444249	10mg	$425	Buy
444249	25mg	$672	Buy
254937	10mg	$446	Buy

(E)-(+/-)-2-Amino-4-methyl-5-phosphono-3-pentenoic acid ethyl ester Chemical Properties,Uses,Production

Uses

CGP 39551 is a potent, selective and competitive NMDA antagonist.

Biological Activity

Potent, selective and competitive NMDA antagonist (K i = 310 nM for inhibition of [ 3 H]-CPP binding in rat brain). Centrally active upon oral administration in vivo .

in vivo

CGP 39551 exhibits maximal electroshock-induced seizures in mice with the ED₅₀ of 4 mg/kg (p.o.)^[2].
Following chronic neonatal treatment with CGP 39551, adult rats show increased behavioral responses to the D2 dopamine receptor stimulation^[3].

storage

Desiccate at +4°C

(E)-(+/-)-2-Amino-4-methyl-5-phosphono-3-pentenoic acid ethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

(E)-(+/-)-2-Amino-4-methyl-5-phosphono-3-pentenoic acid ethyl ester Suppliers

Global( 44)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
J & K SCIENTIFIC LTD.	18210857532 18210857532	jkinfo@jkchemical.com	China	96815	76
3B Pharmachem (Wuhan) International Co.,Ltd.	18930552037	3bsc@sina.com	China	15813	69
Ascent Scientific	4401179829988	customerservice@ascentscientific.co.uk	United Kingdom	279	60
Shanghai Aladdin Bio-Chem Technology Co.,LTD	400-6206333 13167063860	anhua.mao@aladdin-e.com	China	29985	65
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8435	60
Shanghai YuanYe Biotechnology Co., Ltd.	15026964105	2881489226@qq.com	China	89667	60
BOC Sciences	16314854226; +8616314854226	inquiry@bocsci.com	United States	19852	58
TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	marketing@targetmol.com	United States	32431	58
Nextpeptide Inc	+86-0571-81612335 +8613336028439	sales@nextpeptide.com	China	19904	58
Career Henan Chemica Co	+86-0371-86658258 +86-13203830695	laboratory@coreychem.com	China	30203	58

Supplier	Advantage
J & K SCIENTIFIC LTD.	76
3B Pharmachem (Wuhan) International Co.,Ltd.	69
Ascent Scientific	60
Shanghai Aladdin Bio-Chem Technology Co.,LTD	65
EMMX Biotechnology LLC	60
Shanghai YuanYe Biotechnology Co., Ltd.	60
BOC Sciences	58
TargetMol Chemicals Inc.	58
Nextpeptide Inc	58
Career Henan Chemica Co	58

127910-32-1((E)-(+/-)-2-Amino-4-methyl-5-phosphono-3-pentenoic acid ethyl ester)Related Search:

(E)-(+/-)-2-Amino-4-methyl-5-phosphono-3-pentenoic acid ethyl ester (E)-(+/-)-2-Amino-4-methyl-5-phosphono-3-pentenoic acid 3-Pentenoic acid 3-Pentenoic acid GluN1(356-385)

CGP 39551 (E)-(+/-)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID ETHYLESTHER 2-Amino-4-methyl-5-phosphono-3 pentenoic acid carboxyethyl ester 3-Pentenoic acid, 2-amino-4-methyl-5-phosphono-, 1-ethyl ester, (3E)- 3-Pentenoic acid, 2-amino-4-methyl-5-phosphono-, 1-ethyl ester, (E)-(+-)- (E)-(4-Amino-5-ethoxy-2-methyl-5-oxopent-2-en-1-yl)phosphonic acid CGP 39551, competitive NMDA antagonist (E)-(+/-)-2-Amino-4-methyl-5-phosphono-3-pentenoic acid ethyl ester 127910-32-1 Glutamate receptor Glutamate