4-Bromo-5-fluoro-2-nitroaniline
- CAS No.
- 153505-36-3
- Chemical Name:
- 4-Bromo-5-fluoro-2-nitroaniline
- Synonyms
- 4-Bromo-5-fluoro-2-nitroaniline;4-Bromo-5-fluoro-2-nitroaniline97%;4-Bromo-5-fluoro-2-nitroaniline 97%;4-Bromo-5-fluoro-2-nitrobenzenamine;2-Amino-5-bromo-4-fluoronitrobenzene;Benzenamine,4-bromo-5-fluoro-2-nitro-
- CBNumber:
- CB61563243
- Molecular Formula:
- C6H4BrFN2O2
- Molecular Weight:
- 235.01
- MDL Number:
- MFCD11101433
- MOL File:
- 153505-36-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302+H312+H332 |
| Precautionary statements | P271-P260-P280 |
| Hazard Codes | T |
| HS Code | 2921420090 |
4-Bromo-5-fluoro-2-nitroaniline price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | PC3817 | 4-Bromo-5-fluoro-2-nitroaniline 97% | 153505-36-3 | 500mg | $21 | 2026-06-04 | Buy |
| Activate Scientific | AS91281 | 4-Bromo-5-fluoro-2-nitroaniline 95% | 153505-36-3 | 1g | $29 | 2026-06-04 | Buy |
| Activate Scientific | AS91281 | 4-Bromo-5-fluoro-2-nitroaniline 95% | 153505-36-3 | 5g | $138 | 2026-06-04 | Buy |
| Activate Scientific | AS91281 | 4-Bromo-5-fluoro-2-nitroaniline 95% | 153505-36-3 | 25g | $546 | 2026-06-04 | Buy |
| Matrix Scientific | 207751 | 4-Bromo-5-fluoro-2-nitroaniline | 153505-36-3 | 5.00g | $393 | 2026-05-18 | Buy |
4-Bromo-5-fluoro-2-nitroaniline Chemical Properties,Uses,Production
Synthesis
929279-27-6
153505-36-3
The general procedure for the synthesis of 4-bromo-5-fluoro-2-nitroaniline, using the compound (CAS: 929279-27-6) as starting material, was as follows:Preparation of Intermediate 11B: To (4-bromo-5-fluoro-2-nitrophenyl)-2,2,2-trifluoroacetamide (3.5 g, 10.5 mmol) was added methanol (30 mL), followed by potassium carbonate (1.0 M 10.5 mL, 10.5 mmol). The reaction mixture was stirred for 30 min (Ref. Charifson, PS; et al. J. Med. Chem. 2008, 51, 5243-5263). Upon completion of the reaction, the reaction solution was diluted with deionized water and stirring was continued for 1 hour. The resulting orange solid was collected by filtration and dried in a vacuum oven to give the final target product 4-bromo-5-fluoro-2-nitroaniline (2.1 g, 8.8 mmol, 84% yield).
References
[1] Patent: WO2012/83170, 2012, A1. Location in patent: Page/Page column 154-155
[2] Tetrahedron Letters, 2008, vol. 49, # 44, p. 6348 - 6351
[3] Patent: WO2007/30366, 2007, A1. Location in patent: Page/Page column 121
[4] Patent: US2007/259936, 2007, A1. Location in patent: Page/Page column 175
4-Bromo-5-fluoro-2-nitroaniline Preparation Products And Raw materials
Raw materials
Preparation Products
4-Bromo-5-fluoro-2-nitroaniline Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Nanjing Chemlin Chemical Co., Ltd | 025-83697070 13770331960 | info@chemlin.com.cn | China | 16305 | 64 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 13913916777 | cfzhang@aikonchem.com | China | 19902 | 55 |
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 18201 | 56 |
| SynAsst Chemical. | 021-60343070 | China | 12731 | 55 | |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Xinyanhe Pharmatech Co.,Ltd | 0519-85252752 15366845260 | taihuaren@vip.163.com | China | 1033 | 58 |
| Mashilabs (Shanghai) Co.,Ltd. | 19916721580 | mafarm@126.com | China | 4538 | 58 |
| Shanghai Na Qian Chemical Technology Co. Ltd. | 13598610367 13598610367 | 2841375912@qq.com | China | 3468 | 52 |
