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4-Chlorobutyric acid

4-Chlorobutyric acid Structure
4-Chlorobutyric acid structure
CAS No.
627-00-9
Chemical Name:
4-Chlorobutyric acid
Synonyms
4-Chlorobutanoic acid;NSC 6391;NSC 76578;Cl(CH2)3COOH;Levetiracetam-12;4-ChlorobutyricAci;RARECHEM AL BO 0177;4-Chlorobutanoicacid;4-chloro-butanoicaci;4-clorobutanoic acid
CBNumber:
CB6203041
Molecular Formula:
C4H7ClO2
Molecular Weight:
122.55
MDL Number:
MFCD00002818
MOL File:
627-00-9.mol
MSDS File:
SDS
Last updated:2026-09-12 18:54:01
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4-Chlorobutyric acid Properties

Melting point 12-16 °C(lit.)
Boiling point 196 °C22 mm Hg(lit.)
Density 1.24 g/mL at 25 °C(lit.)
refractive index n20/D 1.451(lit.)
Flash point >230 °F
storage temp. Sealed in dry,Room Temperature
solubility soluble in Ether
pka 4.52(at RT℃)
form clear liquid
color Colorless to Almost colorless
BRN 1700264
InChI InChI=1S/C4H7ClO2/c5-3-1-2-4(6)7/h1-3H2,(H,6,7)
InChIKey IPLKGJHGWCVSOG-UHFFFAOYSA-N
SMILES C(O)(=O)CCCCl
CAS DataBase Reference 627-00-9(CAS DataBase Reference)
EPA Substance Registry System 4-Chlorobutyric acid (627-00-9)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Corrosion (GHS05)Exclamation Mark (GHS07)
GHS05,GHS07
Signal word  Danger
Hazard statements  H302-H314
Precautionary statements  P270-P280-P301+P312-P303+P361+P353-P304+P340+P310-P305+P351+P338
PPE Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
Hazard Codes  C
Risk Statements  22-34
Safety Statements  26-36/37/39-45
RIDADR  UN 3265 8/PG 2
WGK Germany  3
TSCA  TSCA listed
HazardClass  8
PackingGroup  III
HS Code  29159000
Storage Class 8A - Combustible corrosive hazardous materials
Hazard Classifications Acute Tox. 4 Oral
Skin Corr. 1B
NFPA 704
1
3 0

4-Chlorobutyric acid price More Price(32)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich C29835 4-Chlorobutyric acid 99% 627-00-9 25g $130 2026-04-30 Buy
Sigma-Aldrich C29835 4-Chlorobutyric acid 99% 627-00-9 100g $316 2026-04-30 Buy
TCI Chemical C0651 4-Chlorobutyric Acid >95.0%(T) 627-00-9 25g $58 2026-04-30 Buy
TCI Chemical C0651 4-Chlorobutyric Acid >95.0%(T) 627-00-9 500g $412 2026-04-30 Buy
Biosynth FC164688 4-Chlorobutyric acid 627-00-9 50g $900 2026-06-04 Buy
Product number Packaging Price Buy
C29835 25g $130 Buy
C29835 100g $316 Buy
C0651 25g $58 Buy
C0651 500g $412 Buy
FC164688 50g $900 Buy

4-Chlorobutyric acid Chemical Properties,Uses,Production

Chemical Properties

Dark brown liquid

Uses

4-Chlorobutanoic Acid is an impurity of Levetiracetam(L331500) which is (S)-enantiomer of Etiracetam (E932970) and the ethyl analog of Piracetam (P500800). Used as an anticonvulsant. Neuroprotective & Neuroresearch Product.

Synthesis Reference(s)

Journal of the American Chemical Society, 92, p. 5274, 1970 DOI: 10.1021/ja00720a076
The Journal of Organic Chemistry, 21, p. 883, 1956 DOI: 10.1021/jo01114a016

Synthesis

The target compound 4-chloropropionic acid was hydrolyzed from 4-chlorobutyryl chloride prepared by ring opening using -butyrolactone as the starting material.

4-Chlorobutyric acid synthesis

96-48-0
627-00-9
Synthesis of 4-Chlorobutyric acid from Gamma Butyrolactone

4-Chlorobutyric acid Preparation Products And Raw materials

Raw materials

Preparation Products

4-(1,3-Dioxo-1,3-dihydro-2H-isoindol-2-yl)butanoic acid 4-(benzylthio)butanoic acid

4-Chlorobutyric acid Suppliers

Global( 275)Suppliers
Supplier Tel Email Country ProdList Advantage
Hangzhou Aiken New Materials Co., Ltd 15258847994 andriy@akkochemical.com China 242 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Ark Pharm, Inc. 847-367-3680 sales@arkpharminc.com United States 1669 56
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
Nanjing Chemlin Chemical Co., Ltd 025-83697070 13770331960 info@chemlin.com.cn China 16305 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Chembon Pharmaceutical Co., Ltd. 028-84252981 18583719936 sales@chembon.com.cn China 854 64
Supplier Advantage
Hangzhou Aiken New Materials Co., Ltd 58
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
TCI (Shanghai) Development Co., Ltd. 81
Ark Pharm, Inc. 56
Energy Chemical 61
Pure Chemistry Scientific Inc. 62
Nanjing Chemlin Chemical Co., Ltd 64
Shanghai Hanhong Scientific Co.,Ltd. 64
Chembon Pharmaceutical Co., Ltd. 64

View Lastest Price from 4-Chlorobutyric acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-CHLOROBUTYRIC ACID pictures 2026-09-02 4-CHLOROBUTYRIC ACID
627-00-9
 $5.00-8.00 1KG 99% Henan Fengda Chemical Co., Ltd
4-CHLOROBUTYRIC ACID pictures 2026-06-30 4-CHLOROBUTYRIC ACID
627-00-9
 1kg 99% 10000KGS Shaanxi Dideu New Materials Co. Ltd
4-CHLOROBUTYRIC ACID pictures 2021-07-13 4-CHLOROBUTYRIC ACID
627-00-9
 $10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd

4-Chlorobutyric acid Spectrum

4-CHLOROBUTYRIC ACID(627-00-9)MS4-CHLOROBUTYRIC ACID(627-00-9)1HNMR4-CHLOROBUTYRIC ACID(627-00-9)13CNMR4-CHLOROBUTYRIC ACID(627-00-9)IR14-CHLOROBUTYRIC ACID(627-00-9)Raman

627-00-9(4-Chlorobutyric acid)Related Search:

2-Chloropropionic acid (S)-(-)-2-Chloropropionic acid Ethyl 4-chlorobutyrate (2S)-2-(2-Oxopyrrolidin-1-yl)butanoic acid L(+)-2-Aminobutyric acid
LevetiracetaM IMpurity B (S)-N-(1-aMino-1-oxobutan-2-yl)-4-chlorobutanaMide 2-aminobutanenitrile alpha-Ethyl-2-oxo-1-pyrrolidineacetic acid 1,3-dihydroxypropan-2-yl 4-hydroxybenzoate
(S)-2-Aminobutyramide hydrochloride 2,3-dihydroxypropyl 4-hydroxybenzoate 2-Hydroxypyridine (R)-2-(2-OXO-PYRROLIDIN-1-YL)-BUTYRAMIDE Gamma Butyrolactone
Sodium 4-hydroxybutyrate (R)-(-)-2-Aminobutanamide hydrochloride, 97% H-Abu-OMe HCl

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4-chloro-butanoicaci 4-Chlorobutanoicacid 4-chloro-Butanoicacid Butyric acid, 4-chloro- Cl(CH2)3COOH gamma-Chloro-n-butyric acid Levetiracetam-12 GAMMA-CHLOROBUTYRIC ACID 4-CHLOROBUTYRIC ACID 99% 4-CHLORO-N-BUTYRIC ACID RARECHEM AL BO 0177 4-clorobutanoic acid Butanoic acid,4-chloro- NSC 6391 NSC 76578 4-Chlorobutyric Acid > 4-Chlorobutanoic acid (Levetiracetam Impurity) Levetiracetam impurities511 Levetiracetam impurities5 4-ChlorobutyricAci 4-Chlorobutanoic acid 4-Chlorobutyric acid 627-00-9 ClC3H6COOH 蠅-Chlorocarboxylic Acids 蠅-Functional Alkanols, Carboxylic Acids, Amines & Halides CARBOXYLIC ACID Organic Building Blocks Building Blocks C1 to C5 Carboxylic Acids Carbonyl Compounds omega-Chlorocarboxylic Acids omega-Functional Alkanols, Carboxylic Acids, Amines & Halides C1 to C5 Carbonyl Compounds Carboxylic Acids