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Tetrahydrobiopterin

CAS No.
17528-72-2
Chemical Name:
Tetrahydrobiopterin
Synonyms
bh4;6R-BH4;THB, 2HCL;(6R)-BH4 2HCL;BH4 DIHYDROCHLORIDE;Tetrahydrobiopterin;5,6,7,8-Tetrahydrobiopterin;Bendroflumethiazide Impurity 3;TETRAHYDRO-L-BIOPTERIN, DIHYDROCHLORIDE;(6R)-5,6,7,8-TETRAHYDRO-BIOPTERIN DIHYDROCHLORIDE
CBNumber:
CB6206284
Molecular Formula:
C9H15N5O3
Molecular Weight:
241.25
MDL Number:
MFCD00214397
MOL File:
17528-72-2.mol
MSDS File:
SDS
Last updated:2026-08-20 20:20:01

Tetrahydrobiopterin Properties

Melting point >202°C (dec.)
Boiling point 506.6±60.0 °C(Predicted)
Density 1.89±0.1 g/cm3(Predicted)
storage temp. -20°C
solubility Aqueous Acid (Slightly), DMSO (Slightly), Water (Slightly)
pka 14.22±0.20(Predicted)
form Solid
color White to Off-White
Stability Hygroscopic
FDA UNII EGX657432I

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
Toxicity mouse,LD50,intraperitoneal,258mg/kg (258mg/kg),Toxicology. Vol. 42, Pg. 183, 1986.

Tetrahydrobiopterin price More Price(18)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 371067 Sapropterin Dihydrochloride ≥97%(HPLC) 17528-72-2 50mg $305 2026-06-03 Buy
Usbiological 371067 Sapropterin Dihydrochloride ≥97%(HPLC) 17528-72-2 100mg $418 2026-06-03 Buy
Usbiological 371067 Sapropterin Dihydrochloride ≥97%(HPLC) 17528-72-2 250mg $662 2026-06-03 Buy
ChemScene CS-7811 Tetrahydrobiopterin 98.08% 17528-72-2 5mg $125 2026-06-04 Buy
ChemScene CS-7811 Tetrahydrobiopterin 98.08% 17528-72-2 10mg $200 2026-06-04 Buy
Product number Packaging Price Buy
371067 50mg $305 Buy
371067 100mg $418 Buy
371067 250mg $662 Buy
CS-7811 5mg $125 Buy
CS-7811 10mg $200 Buy

Tetrahydrobiopterin Chemical Properties, Uses, Production

Uses

Tetrahydrobiopterin is a naturally occurring essential cofactor of the three aromatic amino acid hydroxylase enzymes, used in the degradation of amino acid phenylalanine and in the biosynthesis of the neurotransmitters serotonin, melatonin, dopamine, norepinephrine , epinephrine, and is a cofactor for the production of nitric oxide by the nitric oxide synthases. Chemically, its structure is that of a reduced pteridine derivative.

Definition

ChEBI: 5,6,7,8-tetrahydrobiopterin is a tetrahydropterin, a member of biopterins and a diol. It has a role as a prosthetic group, a coenzyme, a nutraceutical and a human metabolite.

Tetrahydrobiopterin Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 118)
Supplier Tel Email Country ProdList Advantage
Chembest Research Laboratories Limited 021-20908456 sales@BioChemBest.com China 5996 61
LGM Pharma 1-(800)-881-8210 inquiries@lgmpharma.com United States 2110 70
Guangzhou Kuwei Technology Co., Ltd. 15013362837 yxusmith@aliyun.com China 6 52
Changzhou Joyous Chemical Co., Ltd. 0519-85607258 sales@joyouschem.com China 292 60
Shanghai T&W Pharmaceutical Co., Ltd. +86 21 61551611 China 9874 58
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4853 58
GIHI CHEMICALS CO.,LTD 0086-571-86217390 Sales@gihichem.com China 858 58
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 18149758185 sales-cpd@caerulumpharma.com China 3493 58
Nanjing Credit Trading Co.,Ltd 025-52164950 Googlexu_0114@sina.com China 644 58
Quality Control Solutions Ltd. 0755-66853366 13670046396 orders@qcsrm.com China 18188 56

View Latest Price from Tetrahydrobiopterin manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Tetrahydrobiopterin pictures 2026-08-18 Tetrahydrobiopterin
17528-72-2
$98.00 99.82% 10g TargetMol Chemicals Inc.
Tetrahydrobiopterin pictures 2025-06-20 Tetrahydrobiopterin
17528-72-2
$40.00 1kg 0.99 10 tons Hebei Yanxi Chemical Co., Ltd.
Tetrahydrobiopterin pictures 2024-12-24 Tetrahydrobiopterin
17528-72-2
1Kg 99.9% 200tons airuikechemical co., ltd.
5,6,7,8-tetrahydro-2-amino-6-(1,2-dihydroxypropyl)-4(1h)-pteridinon 5,6,7,8-tetrahydro-2-amino-6-(1,2-dihydroxypropyl)-4(1h)-pteridinone TETRAHYDRO-L-BIOPTERIN, DIHYDROCHLORIDE THB, 2HCL 6R-BH4 (6R)-BH4 2HCL [6R-[6R*(1R*,2S*)]]-2-AMINO-6-(1,2-DIHYDROXY-PROPYL)-5,6,7,8-TETRAHYDRO-4(1H)-PTERIDINONE DIHYDROCHLORIDE (6R)-5,6,7,8-TETRAHYDRO-L-BIOPTERIN DIHYDROCHLORIDE (6R)-5,6,7,8-TETRAHYDRO-BIOPTERIN DIHYDROCHLORIDE 6-BETA-5,6,7,8-TETRAHYDRO-L-BIOPTERIN DIHYDROCHLORIDE 2-AMINO-6R-(1R,2S-DIHYDROXYPROPYL)-5,6,7,8-TETRAHYDRO-4(1H)-PTERIDINONE, DIHYDROCHLORIDE BH4 DIHYDROCHLORIDE (6R)-2-Amino-6β-[(1S,2R)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydropteridin-4(1H)-one (6R)-2-Amino-6β-[(1S,2R)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydropteridin-4(3H)-one 2-Amino-6-(1,2-dihydroxypropyl)-3,4,5,6,7,8-hexahydropteridine-4-one 2-Amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4(1H)-pteridinone (6R)-2-AMino-6-[(1R,2S)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydro-4(1H)-pteridinone 4(3H)-Pteridinone,2-aMino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydro- 2-amino-6-(1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-1H-pteridin-4-one 5,6,7,8-Tetrahydrobiopterin Tetrahydrobiopterin Bendroflumethiazide Impurity 3 bh4 17528-72-2 C9H15N5O3 Analytical Chromatography Product Catalog Alphabetic Analytical Standards TA - TE