n-Docosanol
- CAS No.
- 661-19-8
- Chemical Name:
- n-Docosanol
- Synonyms
- BEHENYL ALCOHOL;DOCOSANOL;1-DOCOSANOL;Behenic alcohol;Docosan-1-ol;BEHENYL;DOCOSANOL, N-;behenicalcohol;BEHENYLIC ALCOHOL;ik2
- CBNumber:
- CB6219657
- Molecular Formula:
- C22H46O
- Molecular Weight:
- 326.6
- MDL Number:
- MFCD00002939
- MOL File:
- 661-19-8.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 65-72 °C(lit.) |
|---|---|
| Boiling point | 180 °C0.22 mm Hg(lit.) |
| Density | d75 0.8063 g/ml; d85 0.7986 g/ml; d95 0.7911 g/ml |
| vapor pressure | 0Pa at 25℃ |
| refractive index | n75 1.4360 |
| storage temp. | Store below +30°C. |
| solubility | Chloroform (Slightly), Ethyl Acetate (Slightly) |
| pka | 15.20±0.10(Predicted) |
| form | Pellets or Tablets |
| color | White |
| Viscosity | 9.7mm2/s |
| Water Solubility | Insoluble |
| Merck | 13,3433 |
| BRN | 1770470 |
| Henry's Law Constant | 6.2×10-3 mol/(m3Pa) at 25℃, HSDB (2015) |
| Stability | Stable. Combustible. Incompatible with strong oxidizing agents. |
| Cosmetics Ingredients Functions |
SKIN CONDITIONING - EMOLLIENT BINDING VISCOSITY CONTROLLING EMULSION STABILISING |
| Cosmetic Ingredient Review (CIR) | n-Docosanol (661-19-8) |
| InChI | 1S/C22H46O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-22-23/h23H,2-22H2,1H3 |
| InChIKey | NOPFSRXAKWQILS-UHFFFAOYSA-N |
| SMILES | CCCCCCCCCCCCCCCCCCCCCCO |
| LogP | 8.3 at 20℃ |
| CAS DataBase Reference | 661-19-8(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | 9G1OE216XY |
| NIST Chemistry Reference | 1-Docosanol(661-19-8) |
| EPA Substance Registry System | 1-Docosanol (661-19-8) |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H410-H319 | |||||||||
| Precautionary statements | P273-P391-P501-P264-P280-P305+P351+P338-P337+P313P | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Safety Statements | 24/25 | |||||||||
| WGK Germany | - | |||||||||
| RTECS | JR1315000 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29051900 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazardous Substances Data | 661-19-8(Hazardous Substances Data) | |||||||||
| Toxicity | LD50 intraperitoneal in mouse: > 800mg/kg | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
n-Docosanol price More Price(71)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHR2264 | Docosanol(n-Docosanol) PharmaceuticalSecondaryStandard;CertifiedReferenceMaterial | 661-19-8 | 1G | $209 | 2026-04-30 | Buy |
| Sigma-Aldrich | 8.22047 | 1-Docosanol for synthesis | 661-19-8 | 100g | $79.2 | 2026-04-30 | Buy |
| Sigma-Aldrich | 169102 | 1-Docosanol 98% | 661-19-8 | 50g | $86.6 | 2026-04-30 | Buy |
| TCI Chemical | D0964 | 1-Docosanol >98.0%(GC) | 661-19-8 | 25g | $42 | 2026-04-30 | Buy |
| TCI Chemical | D0964 | 1-Docosanol >98.0%(GC) | 661-19-8 | 500g | $211 | 2026-04-30 | Buy |
n-Docosanol Chemical Properties, Uses, Production
Chemical Properties
1-DOCOSANOL is white powder
Uses
antiviral
Uses
n-Docosanol is a binder and an emulsion stabilizer. It is also used to increase a formulation’s viscosity. This is a mixture of fatty alcohols. behenyl alcohol may be used for any number of purposes in a cosmetic formulation, including as an emollient, a binder, an emulsion stabilizer, or to increase a product’s viscosity. It may be derived either synthetically or from plants.
Uses
1-Docosanol works as a surfactant in cosmetics. 1-Docosanol cream has also been approved by the US Food and Drug Administration as a safe and effective topical treatment for herpes labialis
Indications
Docosanol (Abreva) is a long-chain saturated alcohol
that is clinically effective against HSV. It has in vitro activity
against many enveloped viruses, including CMV,
influenzavirus, and respiratory syncytial virus.
Docosanol is not directly virucidal; instead, it blocks
the entry of the virion into the host cell by inhibiting the
fusion of the viral envelope with the host plasma membrane.
Because it does not affect viral replication or protein
production, it may be less susceptible to the development
of resistance than other antiviral drugs.
Definition
1-DOCOSANOL is a long-chain, saturated fatty alcohol.
General Description
1-Docosanol inhibits replication of certain viruses (herpes simplex virus and respiratory syncytial virus) within primary target cells in vitro. It has been isolated from Clematis brevicaudata.
Flammability and Explosibility
Not classified
Pharmaceutical Applications
1-DOCOSANOL is a 22-carbon straight chain alcohol licensed for over-thecounter sales for the topical treatment of herpes labialis. It is thought to act by blocking viral fusion with the host cell, although definitive studies are lacking. The clinical relevance of the antiviral activity has been debated and the place of this medication as a treatment of herpes labialis remains to be established.
Clinical Use
Docosanol cream is approved for the over-the-counter treatment of herpes labialis. It shortens the duration of symptoms of cold sores and fever blisters but does not provide symptomatic relief.
Side effects
Adverse effects of docosanol are minimal. Skin irritation occurs infrequently. Drug interactions are not anticipated.
Purification Methods
Crystallise docosanol from ether or chloroform/ether. [Beilstein 1 IV 1906.]
n-Docosanol Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Guangzhou Rui Lion Biotechnology Co., LTD | 13168345686 17306666488 | 607141423@qq.com | China | 1725 | 58 |
| Shanghai shengyue international trading co., ltd | 021-66690837 13166269258 | 2570384992@qq.com | China | 53 | 58 |
| Jiangsu Runfeng Synthetic Technology Co., Ltd. | 0513-66017678 18551497631 | 507167383@qq.com | China | 4979 | 58 |
| Jiangsu Pules Bio-tech Co.,Ltd | 0513-66017706 18551496367 | 2186883463@qq.com | China | 4976 | 58 |
| CHEMBSF (Shanghai) Biomedical Technology Co., Ltd | 60662071 18117346937 | 18117346937@163.com | China | 4932 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Chemvon Biotechnology Co., Ltd | 021-50790412 | info@chemvon.com | China | 371 | 57 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Ark Pharm, Inc. | 847-367-3680 | sales@arkpharminc.com | United States | 1669 | 56 |
Related articles
- Preclinical toxicology studies and Pharmaceutical Applications of n-Docosanol
- n-Docosanol is used in the cosmetics industry as an emollient, emulsifier, and thickener. It also serves as a nutritional supp....
- Mar 13,2026
View Latest Price from n-Docosanol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-18 | n-Docosanol
661-19-8
|
$75.00-100.00 | 1kg | 99% | 5000Ton | HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | |
 |
2026-09-18 | 1-Docosanol
661-19-8
|
$1.00 | 1g | 0.99 | 20 tons | RongNa Biotechnology Co.,Ltd | |
 |
2026-05-28 | n-Docosanol
661-19-8
|
$2.00 | 10kg | 99 % | 10000kg | Hebei Chuanghai Biotechnology Co,.LTD |
-
- n-Docosanol
661-19-8
- $75.00-100.00
- 99%
- HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
-
- 1-Docosanol
661-19-8
- $1.00
- 0.99
- RongNa Biotechnology Co.,Ltd
-
- n-Docosanol
661-19-8
- $2.00
- 99 %
- Hebei Chuanghai Biotechnology Co,.LTD
661-19-8 (n-Docosanol) Related Search:
1of4
